We believe that basic research and the cultivation of scientific knowledge is critical for us to stay connected with our customers and to drive scientific breakthroughs. At NEB, over 30 labs participate in research projects, which are aided by post-doctoral fellows and students in Masters and Ph.D. programs. NEB researchers have authored or co-authored over 1,000 publications (as of 1/17) many of which are in peer-reviewed journals. Further, NEB products have been used successfully in numerous publications by scientists throughout the world.

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Year Title Journal Authors Application(s)
2018 Light-activated chemical probing of nucleobase solvent accessibility inside cells. Nature Chemical Biology Feng, C., Chan, D., Joseph, J., Muuronen, M., Coldren, W.H., Dai, N., Corrêa, I.R., Jr., Furche, F., Hadad, C.M., Spitale, R.C.
2018 Comparative genome and methylome analysis reveals restriction/modification system diversity in the gut commensal Bifidobacterium breve. Nucleic Acids Research Bottacini, F., Morrissey, R., Roberts, R.J., James, J., van Breen, J., Egan, M., Lambert, J., van Limpt, K., Knol, J., O'Connell Motherway, M. and van Sinderen, D.
2018 Core richness of N-glycans of Caenorhabditis elegans: a case study on chemical and enzymatic release Anal. Chem. Yan, S., Vanbeselaere, J., Wöls, F., et. al.
2018 Complete genome sequence and methylome analysis of Bacillus caldolyticus NEB414. Genome Announcements Fomenkov, A., Vincze, T., Mersha, F., Roberts, R.J.
2017 Genetic and epigenetic insight into morphospecies in a reef coral. Molecular Ecology James L. Dimond,Sanoosh K. GamblewoodSteven B. Roberts
2017 Isothermal Amplification of Long, Discrete DNA Fragments Facilitated by Single-Stranded Binding Protein Scientific Reports Zhang Y, Tanner N
2017 Ultrasensitive detection of acute myeloid leukemia minimal residual disease using single molecule molecular inversion probes. Hematologica Adam Waalkes, Kelsi Penewit, Brent L. Wood, David Wu, and Stephen J. Salipante
2017 What is in your cup of tea? DNA Verity Test to characterize black and green commercial teas. PLOS One Olga De Castro , Maria Comparone, Antonietta Di Maio, Emanuele Del Guacchio, Bruno Menale, Jacopo Troisi, Francesco Aliberti, Marco Trifuoggi , Marco Guida
2017 First Report of the Soybean Cyst Nematode, Heterodera glycines, in New York X. Wang, G. C. Bergstrom, S. Chen, D. M. Thurston, and J. A. Cummings, and Z. A. Handoo, M. N. Hult, and A. M. Skantar,
2017 Duplex Alu Screening for Degraded DNA of Skeletal Human Remains Diversity
2017 NEBNext Human Microbiome DNA Enrichment Kit Scientific Reports 5. Thomas, T.
2017 Dynamics of 5-carboxylcytosine during hepatic differentiation: Potential general role for active demethylation by DNA repair in lineage specification Epigenetics Lewis LC et al.
2017 Metabolic Incorporation of Azide Functionality into Cellular RNA Chembiochem Nainar S et al.
2017 Caenorhabditis elegans CES-1 snail represses Pig-1 MELK expression to control asymmetric cell division. Genetics Wei, H., Yan, B., Gagneur, J., Conradt, B.
2017 The gut commensal microbiome of Drosophila melanogaster is modified by the endosymbiont Wolbachia. mSphere Simhardi, R.K., Fast,E.M., Guo, R., Schultz, M.J., Vaisman, N., Ortiz, L., Bybee, J., Slatko, B.E., Frydman, H.M.
2017 The advantages of SMRT™ sequencing.  Genome Biology Roberts, R.J., Carneiro, M.O., Schatz, M.C.
2017 ​Colorimetric tests for diagnosis of filarial infection and vector surveillance using non-instrumented nucleic acid loop-mediated isothermal amplification (NINA-LAMP). PLoS One Poole, C.B., Li, Z., Alhassan, A., Guelig, D., Diesburg, S., Tanner, N.A., Zhang, Y., Evans, T.C. Jr., LaBarre, P., Wanji, S., Burton R.A. and Carlow, C.K.
2017 Examining Sources of Error in PCR by Single-Molecule Sequencing. PLoS ONE Potapov Vladamir, Ong Jennifer L
2017 Rapid Time Scale Analysis of T4 DNA Ligase–DNA Binding. Biochemistry Bauer, R.J., Jurkiw, T.J., Evans, T.C. Jr. and Lohman, G.J.
2017 Methods for structural and functional analyses of intramembrane prenyltransferases in the UbiA superfamily Methods Enzymol Yang, Y., Ke, N., Liu, S., Li, W.
2017 Mechanism and timing of Mcm2-7 ring closure during DNA replication origin licensing Nat. Struct. Mol. Biol. Ticau, S., Friedman, L.J., Champasa, K., Correa, I.R., Jr., Gelles, J., Bell, S.P.
2017 Removing the needle from the haystack: Enrichment of Wolbachia endosymbiont transcripts from host rematode RNA by Cappable-seqTM PLoS One Luck, A.N., Slatko, B.E., Foster, J.M.
2017 NicE-seq: High resolution open chromatin profiling Genome Biology Ponnaluri, V.K.C., Zhang, G., Estève, P.-O., Spracklin, G., Sian, S., Xu, S.-Y., Benoukraf, T., Pradhan, S.
2017 High-throughput biochemical profiling reveals sequence determinants of dCas9 off-target binding and unbinding PNAS Evan A. Boyle, Johan O.L. Andreasson, Lauren M. Chircus, Samuel H. Sternberg, Michelle J. Wu, Chantal K. Guegler, Jennifer A. Doudna, and William J. Greenleaf
2017 Genome Announce Genome Announce. Fomenkov, A., Akimov, V.N., Vasilyeva, L.V., Andersen, D.T., Vincze, T., Roberts, R.J.
2017 Macrocycle peptides delineate locked-open inhibition mechanism for micoorganism phosphoglycerate mutases Nat. Commun. Yu, H., Dranchak, P., Li, Zhiru, MacArthur, R., Munson, M.S., Mehzabeen, N., Baird, N.J., Battalie, K.P., Ross, D., Lovell, Sc., Carlow, C.K.S., Suga, H., Inglese, J.
2017 Highly specific imaging of mRNA in single cells by target RNA-initiated rolling circle amplification Chem Sci Deng, Ruijie., Zhang, Kaixiang., Sun, Yupeng., Ren, Xiaojun., Li, Jinghong.
2017 The GAN exonuclease, or the flap endonuclease Fen1 and RNase HII are necessary for viability of Thermococcus kodakarensis J. Bacteriol Burkhart, B.W., Cubonova, L., Heider, M.R., Kelman, Z., Reeve, J.N., Santangelo, T.J.
2017 Targeted enrichment and sequencing of recent endosymbiont-host lateral gene transfers Sci Rep. Dunning Hotopp, J.C., Slatko, B.E., Foster, J.M.
2017 Whole genome amplification provides suitable control DNA for use in DNA barcoding applications Biop. Bourque, D.A., Naaum, A.M., Distel, D.L., Hanner, R.H.
2017 Various Mutations compensate for a deleterious lacZα insert in the replication enhancer of M13 bacteriophage PLoS One Zygiel, E.M., Noren, K.A., Adamkiewicz, M.A., Aprile, R.J., Bowditch, H.K., Carroll, C.L., Cerezo, M.A.S., Dagher, A.M., Hebert, C.R., Hebert, L.E., Mahame, G.M., Milne, S.C., Silvestri, K.M., Sutherland, S.E., Sylvia, A.M., Taveira, C.N., VanValkenburgh, D.J., Noren, C.J., Hall, M.F.
2017 Rpn (YhgA-Like) Proteins of Escherichia coli K-12 and their Contribution to Rec-A-Independent Horizontal Transfer J. Bacteriol Kingston, A.W., Ponkratz, C. and Raleigh, E.A.
2017 Restriction endonuclease AgeI is a monomer which dimerizes to cleave DNA Nucleic Acids Res. Tamulaitiene, G., Jovaisaite, V., Tamulaitis, G., Songailiene, I., Manakova, E., Zaremba, M., Grazulis, S., Xu, S.Y., Siksnys, V.
2017 Serotyping dengue virus with isothermal amplification and a portable sequencer Scientific Reports Yamagishi, J., et al.
2017 Sequential formation of two branched intermediates during protein splicing of class three inteins Extrmophiles Tori, K. and Perler, F.
2017 Association of 5-hydroxymethylation and 5-methylation of DNA cytosine with tissue-specific gene expression Epigenetics Ponnaluri, V.K., Ehrlich, K.C., Zhang, G., Lacey, M., Johnston, D., Pradhan, S., Ehrlich, M.
2017 A refined DNA methylation detection method using MspJI coupled quantitative PCR Analytical Biochemistry Petell, C.J., Loiseau, G., Gandy, R., Pradhan, S., Gowher, H.
2017 Complete genome sequence and methylome analysis of Acinetobacter calcoaceticus 65 Fomenkov, A., Vincze, T., Degtyarev, S.K., Roberts, R.J.
2017 Complete genome and methylome sequences of Salmonella enterica subsp. enterica Serovars Typhimurium, Saintpaul, and Stanleyville from the SARA/SARB collection Genome Announce Yao, K., Roberts, R.J., Allard, M.W., Hoffmann, M.
2017 A practical guide to the oral microbiome and its relation to health and disease Krishnan, K., Chen, T., Paster, B.J.
2017 EcoBLMcrX, a classical modification-dependent restriction enzyme in Escherichia coli B: Characterization in vivo and in vitro with a new approach to cleavage site determination PLoS One Fomenkov, A., Sun, Z., Dila, D.K., Anton, B.P., Roberts, R.J., Raleigh, E.A.
2017 Dynamics of 5-carboxylcytosine during hepatic differentiation: potential general role for active demethylation by DNA repair in lineage specification Lewis, L.C., Lo, P.C., Foster, J.M., Dai, N., Correa, I.R., Jr., Durczak, P.M., Duncan, G., Ramsawhook, A., Aithal, G.P., Denning, C., Hannan, N.R., Ruzov, A.
2017 Functional characterisation of cis-regulatory elements governing dynamic Eomes expression Development Simon, C.S. et al.
2017 Evaluating computatonal gene ontology annotations Methods Mol. Biol. Skunca, N., Roberts, R.J., Steffen, M.
2017 DNA damage is a pervasive cause of sequencing errors, directly confounding variant identification Science Chen, L., Liu, P., Evans, T.C., Jr., Ettwiller, L.M.
2017 Defining the RNaseH2 enzyme-initiated ribonucleotide excision repair pathway in Archaea J. Biol Chem. Heider, M.R., Burkhart, B.W., Santangelo, T.J., Gardner, A.F.
2017 DNA target recognition domains in the Type I restriction and modification systems of Staphylococcus aureus Nucl. Acids Res. Cooper, L.P., Roberts, G.A., White, J.H., Luyten, Y.A., Bower, E.K., Morgan, R.D., Roberts, R.J., Lindsay, J.A., Dryden, D.T.
2017 DNA recognition by the SwaI restriction endonuclease involves unusual distortion of an 8 base pair A:T-rich target Nucl. Acids Res. Shen, B.W., Heiter, D.F., Lunnen, K.D., Wilson, G.G., Stoddard, B.L.
2017 De novo assembly of genomes from long sequence reads reveals uncharted territories of Propionibacterium freudenreichii BMC Genomics Deptula, P., Laine, P.K., Roberts, R.J., Smolander, O.-P., Vihinen, H., Piironen, V., Paulin, L., Jokitalo, E., Savijoki, K., Auvinen, P., Varmanen, P.
2017 Restriction-modification mediated barriers to exogenous DNA uptake and incorporation employed by Prevotella intermedia Johnston, C.D., Skeete, C.A., Fomenkov, A., Roberts, R.J., Rittling, S.R.