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We believe that basic research and the cultivation of scientific knowledge is critical for us to stay connected with our customers and to drive scientific breakthroughs. At NEB, over 30 labs participate in research projects, which are aided by post-doctoral fellows and students in Masters and Ph.D. programs. NEB researchers have authored or co-authored over 1,000 publications (as of 1/17) many of which are in peer-reviewed journals. Further, NEB products have been used successfully in numerous publications by scientists throughout the world.

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Year Title Journal Authors Application(s)
2009 "Adenosine Triphosphate Stimulates Aquifex aeolicus MutL Endonuclease Activity" PLoS ONE Mauris, J., & Evans, J
"Bacterial Systems" introduction of Membrane Proteins - Strategies for Expression and Isolation Samuelson, J.C.
2011 "First Generation" automated DNA sequencing technology Curr. Prot. Mol. Biol. Slatko, B.E., et al.
1999 "Protein Splicing" The Encyclopedia of Molecular Biology Perler, F.B., Xu, M.and Noren, C.J.
2011 "Recent Developments in Difficult Protein Expression: A Guide to E.coli strains, Promoters and Relevant Host Mutations" editors Tom C.Evans Jr.and Ming-Qun Xu, Humana Press Methods Mol.Biol. Samuelson, J.C.
2011 "The Molecular Biology, Immunology and chemotherapy of Wolbachia bacterial endosymbionts of filarial nematodes". Parasitic Nematodes: Molecular Biology, Biochemistry & Immunology (Kennedy, M.and Harnett, W., eds.) Foster, J.M., Hoerauf, A., Slatko, B.E.and Taylor, M.J.
2009 "Translational Recoding" The Wiley Encyclopedia of Chemical Biology, Tadhg P.Begley, Ed Osborne, E.M.and Noren, C.J.
2008 13C-sialic acid labeling of glycans on glycoproteins using ST6Gal-I J. Am. Chem Soc. Macnaughtan, M.A., Tian, F., Liu, S., Meng, L., Park, S., Azadi, P., Moremen, K.W., Prestegard, J.H.
2011 5-aza-2'-deoxycytidine and interleukin-1 cooperate to regulate matrix metalloproteinase-3 gene expression. Int.J.Cancer Couillard, J., Estève, P.O., Pradhan, S.and St-Pierre, Y.
2011 5-Hydroxymethylcytosine is associated with enhancers and gene bodies in human embryonic stem cells Gen. Biol. Stroud, H., et al.
2011 6-Thioguanine reactivates epigenetically silenced genes in acute lymphoblastic leukemia cells by facilitating proteasome-mediated degradation of DNMT1 Canc. Res.
2011 6-Thioguanine Reactivates Epigenetically Silenced Genes in Acute Lymphoblastic Leukemia Cells by Facilitating Proteasome-mediated Degradation of DNMT1 Cancer Res. Yuan, B., Zhang, J., Wang, H., Xiong, L., Cai, Q., Wang, T., Jacobsen, S., Pradhan, S. andd Wang, Y.
2004 A bacteriophage-based genetic system for selection of non-splicing inteins. Appl.Environ.Microbiol. Cann, I.K.O., Amaya, K.R., Southworth, M.W.and Perler, F.B.
2008 A cell-based luciferase assay amenable to high-throughput screening of inhibitors of arenavirus budding Virology Capul, A.A. and de la Torre, J.C.
2008 A cell-based luciferase assay amenable to high-throughput screening of inhibitors of arenavirus budding. Virology Capul, A.A. and de la Torre, J.C.
2009 A chemical genetic method for generating bivalent inhibitors of protein kinases J. Am. Chem. Soc. Hill Z. B.
2008 A codon-optimized luciferase from Caussia princeps facilitates the in vivo monitoring of gene expression in the model alga Chlamydomonas reinhardtii. Curr. Genet. Shao, N. and Bock, R.
2008 A codon-optimized luciferase from Gaussia princeps facilitates the in vivo monitoring of gene expression in the model alga Chlamydomonas reinhardtii Curr. Genet. Shao, N. and Bock, R.
2008 A comparative study of protein synthesis in in vitro systems: from the prokaryotic reconstituted to the eukaryotic extract-based. BMC Biotechnol. Hillebrecht, J.R.and Chong, S.
2007 A Concise Synthesis of the Pennsylvania green fluorophore and labeling of intracellular targets with O6-Benzylguanine Derivatives  Org. Lett. Mottram L. F. et al.
2014 A continuous-exchange cell-free protein synthesis system based on extracts from cultured insect cells PLoS One Stech M, Quast RB, Sachse R, Schulze C, Wüstenhagen DA, Kubick S Glycobiology
2007 A covalent chemical genotype-phenotype linkage for in vitro protein evolution ChemBioChem. Stein, V. et al.
2014 A crime against humanity. China Policy Review Roberts, R.J.
1996 A Cyclosporine A-Sensitive Small Molecular-Weight Cyclophilin Of Filarial Parasites. Mol.Biochem.Parasitol. Ma, D., Hong, X.Q., Raghavan, N., Scott, A.L., McCarthy, J.A., Nutman, T.B., Williams, S.A., and Carlow, C.K.S.
2015 A database for DNA restriction and modification: enzymes, genes and genomes. Nucleic Acids Research Roberts, R.J., Vincze, T., Posfai, J., Macelis, D.
2008 A designed protein for the specific and covalent heteroconjugation of biomolecules Bioconj. Chem. Chidley C. et al.
1987 A Developmentally regulated surface epitope expressed by the infective larva of Brugia malayi which is rapidly lost after infection. Molecular Paradigms for Eradicating Helmenthic Parasites Carlow, C.K.S., Perrone, J., Spielman, A., and Philipp, M.A.
2016 A DsbA-Deficient Periplasm Enables Functional Display of a Protein with Redox-Sensitive Folding on M13 Phage. Biochemistry Chen, M., Samuelson, J.C.
2003 A Dual Role for an Aspartic Acid in Glycosylasparaginase Autoproteolysis. Structure Qian, X., Guan, C.and Guo, H.-C.
2003 A fluorescence resonance energy transfer sensor for the beta-domain of metallothionein Proc. Natl. Acad. Sci. USA Hong, S.H., and Maret, W.
2010 A functional NR4A nuclear receptor DNA-binding domain is required for organ development in Caenorhabditis elegans. Genesis Heard, M., Maina, C.V., Morehead, B.E., Hoener, M.C., Nguyen, T.Q., Williams, C.C., Rowan, B.G.and Gissendanner, C.R.
2003 A fusion of disciplines: chemical approaches to exploit fusion proteins for functional genomics Chembiochem Johnsson N. and Johnsson K.
2003 A general method for the covalent labeling of fusion proteins with small molecules in vivo Nature Biotechnology Keppler A. et al.
2006 A genetic dissection of the LlaJI restriction cassette reveals insights on a novel bacteriophage resistance system. BMC Microbiol. O'Driscoll, J., Heiter, D.F., Wilson, G.G., Fitzgerald, G.F., Roberts, R.and van Sinderen, D.
2016 A Genetic Map for the Only Self-Fertilizing Vertebrate. G3 (Bethesda) Kanamori A, Sugita Y, Yuasa Y, Suzuki T, Kawamura K, Uno Y, Kamimura K, Matsuda Y, Wilson CA, Amores A, Postlethwait JH, Suga K, Sakakura Y.
2009 A genetically encoded bioluminescent indicator for the sodium channel activity in living cells J. Am. Chem. Soc. Kaihara, A., Sunami, A., Kurokawa, J., Furukawa, T.
2009 A genetically encoded bioluminescent indicator for the sodium channel activity in living cells J. Am. Chem. Soc. Kaihara, A., Sunami, A., Kurokawa, J. and Furukawa, T.
2004 A genome sequence survey of the filarial nematode Brugia malayi: repeats, gene discovery, and comparative genomics. Mol.Biochem.Parasitol. Whitton, C., Daub, J., Quail, M., Hall, N., Foster, J., Ware, J., Ganatra, M., Slatko, B., Barrell, B.and Blaxter, M.
2009 A genome-scale RNAi screen for Oct4 modulators defines a role of the Pafl complex for embryonic stem cell identity. Cell Stem Cell Ding, L., Paszkowski-Rogacz, M., Nitzsche, A., Slabicki, M.M., Heninger, A.K., de Vries, I., Kittler, R., Junqueira, M., Shevchenko, A., Schulz, H., Hubner, N., Doss, M.X., Sachinidis, A., Hescheler, J., Iacone, R., Anastassiadis, K., Stewart, A.F., Pisabarro, M.T., Caldarelli. A.. Poser, I., Theis, M. and Buchholz, F
2009 A genomescale RNAi screen for Oct4 modulators defines a role of the Paf1 complex for embryonic stem cell identity Cell Stem Cell Ding, L., Paszkowski-Rogacz, M., Nitzsche, A., Slabicki, M.M., Heninger, A.K., de Vries, I., Kittler, R., Junqueira, M., Shevchenko, A., Schulz, H., Hubner, N., Doss, M.X., Sachinidis, A., Hescheler, J., Iacone, R., Anastassiadis, K., Stewart, A.F., Pisabarro, M.T., Caldarelli, A., Poser, I., Theis, M. and Buchholz, F.
2016 A high-throughput assay for the comprehensive profiling of DNA ligase fidelity Nucleic Acids Res. Lohman, G.J., Bauer, R.J., Nichols, N.M., Mazzola, L., Bybee, J., Rivizzigno, D., Cantin, E., Evans, T.C., Jr.
2015 A high-throughput assay for the comprehensive profiling of DNA ligase fidelity Nucleic Acids Res Lohman GJ, Bauer RJ, Nichols NM, Mazzola L, Bybee J, Rivizzigno D, Cantin E, Evans TC Jr.
1998 A highly conserved large molecular weight cyclophilin of filarial parasites. Exp.Parasitol. Hong, X., Ma, D., Page, A.P., Kumar, S.and Carlow, C.K.S.
2011 A highly controllable reconstituted cell-free system--a breakthrough in protein synthesis research Curr. Pharm. Biotechnol. Ohashi, H., Kanamori, T., Shimizu, Y. and Ueda, T.
2010 A highly controllable reconstituted cell-free system--a breakthrough in protein synthesis research Curr. Pharm. Biotechnol. Ohashi, H., Kanamori, T., Shimizu, Y. and Ueda, T.
2007 A highly sensitive assay for monitoring the secretory pathway and ER stress  PLoS One Badr, C.E., Hewett, J.W., Breakefield, X.O. and Tannous, B.A.
2007 A highly sensitive assay for monitoring the secretory pathway and ER stress. PLoS One Badr. C.E., Hewett, J.W., Breakefield, X.Q and Tannous, B.A.
2006 A highly sensitive protein-protein interaction assay based on Gaussia luciferase. Nat. Methods Remy. I. and Michnick, S.W.
2006 A highly sensitive protein-protein interaction assay based onGaussia luciferase Nat. Methods Remy, I. and Michnick, S.W.
2006 A highly sensitive protein-protein interaction assay based onGaussia luciferase Nat. Methods Remy, I. and Michnick, S.W.