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Publications

We believe that basic research and the cultivation of scientific knowledge is critical for us to stay connected with our customers and to drive scientific breakthroughs. At NEB, over 30 labs participate in research projects, which are aided by post-doctoral fellows and students in Masters and Ph.D. programs. NEB researchers have authored or co-authored over 1,000 publications (as of 1/17) many of which are in peer-reviewed journals. Further, NEB products have been used successfully in numerous publications by scientists throughout the world.

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Year Title Journal Authors Application(s)
2001 Molecular Biology Problem Solver: A Laboratory Guide Bonventre, J., Walsh, P.and Robinson, D.
2013 Quantifying Elongation Rhythm during Full-Length Protein Synthesis Rosenblum G, Chen C, Kaur J, Cui X, Zhang H, Asahara H, Chong S, Smilansky Z, Goldman YE, Cooperman BS.
2011 Next-gen expression systems Ritter, A.
2011 Activity, specificity and structure of I-Bth03051: a representative of a new homing endonuclease family Taylor, G.K., Heiter, D.F., Pietrokovski, S. and Stoddard, B.L.
2011 Branched Intermediate Formation is the Slowest Step in th Protein Splicing Reaction of the Ala1 KbA Intein from Methanococcus jannaschii Saleh, L., Southworth, M.W., Considine, N., O'Neill, C., Benner, J., Bollinger, J.M. and Perler, F.B.
2011 6-Thioguanine reactivates epigenetically silenced genes in acute lymphoblastic leukemia cells by facilitating proteasome-mediated degradation of DNMT1 Canc. Res.
2016 Comprehensive Profiling of Glycosphingolipid Glycans Using a Novel Broad Specificity Endoglycoceramidase in a High-Throughput Workflow. Albrecht, S., Vainauskas, S., Stöckmann, H., McManus, C., Taron, C.H. and Rudd, P.M.
2015 Ten simple rules to win a nobel prize Roberts, R.J.
2015 The mRNA decay factor PAT1 functions in a pathway including MAP kinase 4 and immune receptor SUMM2 Roux, M.E., Rasmussen, M.W., Palma, K., Lolle, S., Regue, A.M., Bethke, G., Glazebrook, J., Zhang, W., Sieburth, L., Larsen, M.R., Mundy, J., Petersen, M.
2014 Evaluation of fluorophores to label SNAP-tag fused proteins for multicolor single-molecule tracking microscopy in live cells Bosch PJ, Corrêa IR Jr, Sonntag MH, Ibach J, Brunsveld L, Kanger JS, Subramaniam V
1993 Crystal Structure of the HhaI DNA Methyltransferase. Cheng, X., Kumar, S., Klimasauskas, S., and Roberts, R.J.
1993 Workshop of DNA Probes and PCR for Detection of Filarial Parasies in Vectors Williams, S.A.
1987 Enhancement of the apparent cleavage specificities of restriction endonucleases: applications to megabase mapping of chromosomes. McClelland, M., and Nelson, M.
2012 Metagenome Projects (To be published as part of a proceedings volume based upon a presentation as presented at the VI Congreso Nicaraguense de Biotecnologia.) Slatko, B.
2012 SHuffle, a novel Escherichia coli protein expression strain capable of correctly folding disulfide bonded proteins in its cytoplasm Lobstein, J., Emrich, C.A., Jeans, C., Faulkner, M., Riggs, P. and Berkmen, M.
2010 Lipoprotein biosynthesis as a target for anti-Wolbachia treatment of filarial nematodes. Johnston, K.L., Wu, B., Guimaraes, A., Ford, L.Slatko, B.E.and Taylor, M.J.
2010 Unusual target site disruption by the rare-cutting HNH restriction endonuclease PacI.Structure Shen, B.W., Heiter, D.F., Chan, S.H., Wang, H., Xu, S.Y., Morgan, R.D., Wilson, G.G.and Stoddard, B.L.
2017 Complete genome sequence and methylome analysis of Acinetobacter calcoaceticus 65 Fomenkov, A., Vincze, T., Degtyarev, S.K., Roberts, R.J.
2017 A practical guide to the oral microbiome and its relation to health and disease Krishnan, K., Chen, T., Paster, B.J.
2017 Dynamics of 5-carboxylcytosine during hepatic differentiation: potential general role for active demethylation by DNA repair in lineage specification Lewis, L.C., Lo, P.C., Foster, J.M., Dai, N., Correa, I.R., Jr., Durczak, P.M., Duncan, G., Ramsawhook, A., Aithal, G.P., Denning, C., Hannan, N.R., Ruzov, A.
2017 Restriction-modification mediated barriers to exogenous DNA uptake and incorporation employed by Prevotella intermedia Johnston, C.D., Skeete, C.A., Fomenkov, A., Roberts, R.J., Rittling, S.R.
2008 Expression and purification of BmrI restriction endonucleases and its N-terminal cleavage domain variants Bao, Y., Higgins, Zhang, P., Chan, S.H., Lagaet, S., Sweeney, S., Lunnen, K., Xu, S.Y.
The level of synthesis and secretion of Gaussia princeps
Optimization of Medium Composition for Production pf Recombinant
Targeting of tumor blood vessels
Production of disulfide-bonded proteins in Escherichia coli Berkmen, M.
"Bacterial Systems" introduction of Membrane Proteins - Strategies for Expression and Isolation Samuelson, J.C.
waffles
Rapid Low-Cost Detection of Zika Virus Using Programmable Biomolecular Components
Culture-independent genomic characterisation of Candidatus Chlamydia
Efficient DNA ligation in DNA-RNA hybrid helices by Chlorella
1996 Potent Inhibition Of T7 Rna-Polymerase With A Truncated T7 Promoter. Abstracts Of Papers Of The American Chemical Society Noren, C.J., and Moreira, R.F.
1996 Teaching About Science Accountability in Research Roberts, R.J.
2006 Evolving the substrate specificity of O6 alkylguanine DNA alkyltransferase through loop insertion for applications in molecular imaging ACS Chem Biol. Heinis C. et al.
2007 Chemical tools for biomolecular imaging ACS Chem. Biol. Johnsson N. and Johnsson K.
2009 Chromophore-assisted laser inactivation of α- and γ-tubulin SNAP-tag fusion proteins inside living cells ACS Chem. Biol. Keppler A. et al.
2008 Ribosomal Synthesis of Peptidase-Resistant Peptides Closed by a Nonreducible Inter-Side-Chain Bond ACS Chem. Biol.  Sako, Y., Goto, Y., Murakami, H., and Suga, H.
2010 Photoactivatable and photoconvertible fluorescent probes for protein labeling ACS Chem. Biol. Asap Maurel D. et al.
2007 Genetically encoded short peptide tags for orthogonal protein labeling by Sfp and AcpS phosphopantetheinyl transferases ACS Chemical Biology Zhou Z. et al.
2016 Simple Isothermal Strategy for Multiplexed, Rapid, Sensitive, and Accurate miRNA Detection ACS Sens Wee E J H, Trau M,
2002 Cloning, Expression and Immunization of the new antigen gene Sj-Ts4 of Schistosoma japonicum. Acta Biochimica et Biophysica Sinica Zhou, D.-M., Yi, X.-Y., Zeng, X.-F., Wang, M., Cai, C., Wang, Q.-L., Zhang, S.-K., McReynolds, L.
2003 Crystallization of restriction endonuclease SfiI in complex with DNA Acta Crystallogr. D Biol. Crystallogr. Viadiu, H., Vanamee, E.S., Jacobson, E.M., Schildkraut, I. and Aggarawl, A.K.
2002 Purification and initial crystallization studies of a DnaB intein from Synechocystis sp.PCC 6803. Acta Crystallogr.D.Biol.Crystallogr. Chen, X., Xu, M.-Q., Ding, Y., Ferrandon, S.and Rao, Z.
2002 Crystallographic study of a naturally occurring trans-splicing intein from Synechocystis sp.PCC 6803. Acta Crystallogr.D.Biol.Crystallogr. Chen, X., Xu, M.-Q., Ding, Y., Ferrandon, S.and Rao, Z.
2000 Crystallization and preliminary X-ray diffraction analysis of MspI restriction endonuclease in complex with its cognate DNA. Acta Crystallogr.D.Biol.Crystallogr. O'Loughlin, T.J., Xu, Q., Kucera, R.B., Dorner, L.F., Sweeney, S., Schildkraut, I.and Guo, H.-C.
1999 Purification and crystallization of precursors and autoprocessed enzymes of Flavobacterium glycosylasparaginase: an N-terminal nucleophile hydrolase. Acta Crystallogr.D.Biol.Crystallogr. Cui, T., Liao, P.H., Guan, C.and Guo, H.C.
1999 Crystallization and preliminary diffractin analysis of the HincII restriction endonuclease-DNA complex. Acta Crystallogr.D.Biol.Crystallogr. Horton, N.C, Dorner, L.F., Schildkraut, I.and Perona J.J.
2011 New Clues in the Allosteric Activation of DNA Cleavage by SgrAI; Structures of SgrAI Bound to Cleaved Primary Site DNA and Uncleaved Secondary Site DNA. Acta Crystallogr.F.Structural biology and crystallization communications Little, E.J., Dunten, P.W., Bitinaite, J.and Horton, N.C.
2011 Crystallization and preliminary crystallographic analysis of the Type IIL restriction enzyme MmeI in complex with DNA. Acta Crystallogr.F.Structural biology and crystallization communications Callahan, S.J., Morgan, R.D., Jain, R., Townson, S.A., Wilson, G.,G.Roberts, R.J.and Aggarwal, A.K.
1993 Restriction enzymes from Campylobacter coli strains. Acta gastroenterol.belg. Vitor, J.M.B., Polisson, C., Cabrita, J., and Silva, R.V.C.
1990 Anti-idiotypic antibodies function as a surrogate surface epitope of Brugia malayi infective larvae. Acta Trop. Carlow, C.K.S., Busto, P., Storey, N., and Philipp, M.
2013 Ten eleven translocation enzymes and 5-hydroxymethylation in mammalian development and cancer Adv Exp Med Biol Kinney, S.R. and Pradhan, S.
2009 Protein Splicing: A Versatile Tool for Drug Discovery. Adv.Drug Deliv.Rev. Cheriyan, M.and Perler, F.B.
2005 Automated isolation techniques for microalgae, pgs.101-116 in "Algal culturing techniques" Algal culturing techniques Sieracki, M., Poulton, N., Crosbie, N.
1993 A sensitive serodiagnostic test for onchocerciasis using a cocktail of recombinant antigens. Am J Trop Med Hyg. Bradley, J.E., Trenholme, K.R., Gillespie, A.J., Guderian, R., Titanji, V., Hong, Y., and McReynolds, L.
2010 Biodiversity assessment: State-of-the-art techniques in phylogenomics and species identification Am. J. Bot. Steele, P.R and Pires, J.C.
2010 Massively parallel sequencing of exons on the X chromosome identifies RBM10 as the gene that causes a syndromic form of cleft palate Am. J. Hum. Genet. Johnston, J.J., Teer, J.K., Cherukuri, P.F. et al
2007 Cellular trafficking of phospholamban and formation of functional sarcoplasmic reticulum during myocyte differentiation Am. J. Physiol. Cell Physiol.  Stenoien D. L. et al.
2006 Deglycosylation of the beta1-subunit of the BK channel changes its biophysical properties Am. J. Physiol.Cell. Physiol.  Hagen, B.M., Sanders, K.M.
2007 Tasting Phenylthiocarbamide (PTC): A New Lab With an Old Flavor. Am.Biol.Teacher Merritt, R., Bierwort, L., Slatko, B., Weiner, M., Weiner, E., Ingram, J.and Sciarra, K.
2008 Tasting Phenylthiocarbamide (PTC): A New Lab With an Old Flavor. Am.Biol.Teacher Merritt, R., Bierwort, L., Slatko, B., Weiner, M., Weiner, E., Ingram, J.and Sciarra, K.
1995 Differential recognition of microfilarial chitinase, a transmission-blocking vaccine candidate antigen, by sera from patients with Brigian and Bancroftian filariasis. Am.J.Trop.Med.Hyg. Dissanayake, S., Perler, F.B., Xu, M., Southworth, M.W., Yee, C.K., Wang, S., Dreyer, G., Watawana, L., Kurniawan, L., Fuhrman, J.A., and Piessens, W.F.
1987 Protective immunity to Brugia malayi larvae in BALB/c mice: potential of this model for the identification of protective antigens. Am.J.Trop.Med.Hyg. Carlow, C.K.S., and Philipp, M.
2014 Insights into bacterial CO2 metabolism revealed by the characterization of four carbonic anhydrases in Ralstonia eutropha H16 AMB Express Gai CS, Lu J, Brigham CJ, Bernardi AC, Sinskey AJ Gibson Assembly®
1992 Using Molecular Biological Techniques to Identify and Study Gene Products Involved in Dirofilarial Immunoprophylaxis. American Heartworm Society Hough, D.M., Awobuluyi, M.E., McReynolds, L.A., Carlow, C.K.S., and Maina, C.V.
1994 Restriction and modification. In: Molecular Biology of Bacteriophage T4 American Society for Microbiology, Washington, D.C. Carlson, K., Raleigh, E.A. and Hattman, S.
2010 Phage display probes for imaging early response to bevacizumab treatment Amino Acids Cao, Q. et al. Phage Display
2014 Identification and characterization of mutant clones with enhanced propagation rates from phage-displayed peptide libraries Anal Biochem Nguyen KT, Adamkiewicz MA, Hebert LE, Zygiel EM, Boyle HR, Martone CM, Meléndez-Ríos CB, Noren KA, Noren CJ, Hall MF
2014 Identification and characterization of mutant clones with enhanced propagation rates from phage-displayed peptide libraries Anal Biochem Nguyen KT, Adamkiewicz MA, Hebert LE, Zygiel EM, Boyle HR, Martone CM, Meléndez-Ríos CB, Noren KA, Noren CJ, Hall MF Phage Display
2007 A sensitive fluorescence intensity assay for deubiquitinating proteases using ubiquitin-rhodamine110-glycine as substrate Anal Biochem. Hassiepen, U., et. al.
2002 Recombinant Gaussia luciferase. Overexpression, purification and analytical application of a bioluminescent reporter for DNA hybridization Anal Chem Verhaegen, M., Christopoulos, T.K.
2015 Rapid Preparation of Released N-Glycans for HILIC Analysis Using a Labeling Reagent that Facilitates Sensitive Fluorescence and ESI-MS Detection Anal Chem Lauber, M.A., Yu, Y.Q., Brousmiche,D.W., Hua, Z., Koza, S.M., Magnelli, P., Guthrie, E., Taron, C.H. and Fountain, K.J.
2002 Recombinant Gaussia luciferase. Overexpression, purification, and analytical application of a bioluminescent reporter for DNA hybridization Anal Chem. Verhaegen, M. and Christopoulos, T.K.
2016 Simple and Highly Sensitive Molecular Diagnosis of Zika Virus by Lateral Flow Assays. Anal Chem. Lee D, Shin Y, Chung S, Hwang KS, Yoon DS, Lee JH
2003 Merging fluorescence resonance energy transfer and expressed protein ligation to analyze protein-protein interactions Anal. Biochem.  Scheibner, K.A., Zhang, Z. and Cole, P.A.
2004 SPR-based interaction studies with small molecular weight ligands using hAGT fusion proteins Anal. Biochem. Huber W. et al.
2011 Kinetic study of de novo chromophore maturation of fluorescent proteins Anal. Biochem. Iizuka, R., Yamagishi-Shirasaki, M. and Funatsu, T.
2006 Fluorescence-mediated analysis of mitochondrial preprotein import in vitro Anal. Biochem.  Krayl M. et al.
2010 Multichannel perfusion culture bioluminescence reporter system for longterm detection in living cells Anal. Biochem. Watanabe, T., Enomoto, T., Takahashi, M., Honma, S., Honma, K. and Ohmiya, Y.
2010 Localizable and Highly Sensitive Calcium Indicator Based on a BODIPY Fluorophore Anal. Chem. Kamiya M. and Johnsson K.
2010 Functional Immobilization and Patterning of Proteins by an Enzymatic Transfer Reaction Anal. Chem. Waichman S. et al.
2008 Spectral resolved gene technology for multiplexed bioluminescence and high content screening Anal. Chem. Michelini, E., Cevenini, L., Mezzanote, L., Ablamsky, D., Southworth, T., Branchini, B. and Roda, A.
1998 The Maltoxe-Binding Protein as a Scaffold for Monovalent Display of Peptides Derived from Phage Libraries. Anal.Biochem. Zwick, M.B., Bonnycastle, L.L.C., Noren, K.A., Venturini, S., Leong, E., Barbas, C.F., Noren, C.J.and Scott, J.K.
2008 Single-process expression and purification of multiple recombinant protein through cocultivation and affinity purification. Anal.Biochem. Porte, M.and Chong, S.
2008 Targeting DNA (5)mCpG sites with chimeric endonucleases. Anal.Biochem. Formenkov, A., Too, P.H., Chan, S.H., Vaisvila, R., Cantin, B.A., Mazzola, L., Tam, V.and Xu, S.Y.
2008 A target-unrelated peptide in an M13 phage display library traced to an advantageous mutation in the gene II ribosome-binding site. Anal.Biochem. Brammer, L.A., Bolduc, B., Kass, J.L., Felice, K.M., Noren, C.J.and Hall, M.F.
2016 Genetically anchored fluorescent probes for subcellular specific imaging of hydrogen sulfide. Analyst Chen, J., Zhao, M., Jiang, X., Sizovs, A., Wang, M.C., Provost, C.R., Huang, J. and Wang, J.
2017 A refined DNA methylation detection method using MspJI coupled quantitative PCR Analytical Biochemistry Petell, C.J., Loiseau, G., Gandy, R., Pradhan, S., Gowher, H.
2007 Inducing and sensing protein-protein interactions in living cells by selective cross-linking Angew Chem. Int. Ed Lemercier, G. et al.
2009 Bioorthogonal Chemistry: Fishing for Selectivity in a Sea of Functionality Angew. Chem. Int. Ed. Sletten E. and Bertozzi C.
2000 Dissecting the Chemistry of Protein Splicing and its Applications Angew.Chem.Int.Ed. Noren, C.J., Wang, J.and Perler, F.B.
1995 Photochemically initiated protein splicing. Angew.Chem.Int.Ed.Engl. Cook, S.N., Jack, W.E., Xiong, X., Danley, L.E., Ellman, J.A., Shultz, P.G., and Noren, C.J.
1994 An amazing distortion in DNA induced by a methyltransferase (Nobel lecture) Angew.Chem.Int.Ed.Engl. Roberts, R.J.
1991 Restriction and Modification Systems. Ann.Rev.Genet. Wilson, G.G., and Murray, N.E.
1988 IMMUNITY IN FILARIASIS: Perspectives for Vaccine Development. Ann.Rev.Microbiol. Philipp, M., Davis , T.B., Storey, N., and Carlow, C.K.S.
1998 Base Flipping. Annual Review Biochem. Roberts, R.J.and Cheng, X.
2014 Spontaneous in vitro senescence of glioma cells confirmed by an antibody against IDH1R132H Anticancer Res Stoczynska-Fidelus E, Och W, Rieske P, Bienkowski M, Banaszczyk M, Winiecka-Klimek M, Zieba J, Janik K, Rosiak K, Treda C, Stawski R, Radomiak-Zaluska A, Piaskowski S
2013 Decreased vancomycin susceptibility in Staphylococcus aureus caused by IS256 tempering of WalKR expression Antimicrob Agents Chemother McEvoy CR, Tsuji B, Gao W, Seemann T, Porter JL, Doig K, Ngo D, Howden BP, Stinear TP
2015 Converting a Sulfenic Acid Reductase into a Disulfide Bond Isomerase Antioxid Redox Signal Chatelle C, Kraemer S, Ren G, Chmura H, Marechal N, Boyd D, Roggemans C, Ke N, Riggs P, Bardwell J, Berkmen M
2015 Converting a Sulfenic Acid Reductase into a Disulfide Bond Isomerase Antioxid Redox Signal. Chatelle C, Kraemer S, Ren G, Chmura H, Marechal N, Boyd D, Roggemans C, Ke N, Riggs P, Bardwell J, Berkmen M.