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Publications

We believe that basic research and the cultivation of scientific knowledge is critical for us to stay connected with our customers and to drive scientific breakthroughs. At NEB, over 30 labs participate in research projects, which are aided by post-doctoral fellows and students in Masters and Ph.D. programs. NEB researchers have authored or co-authored over 1,200 publications (as of 1/19) many of which are in peer-reviewed journals. Further, NEB products have been used successfully in numerous publications by scientists throughout the world.

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Year Title Journal Authors Application(s)
1994 Structure of restriction endonuclease BamHI phased at 1.95 A resolution by MAD analysis. Structure Newman, M., Strzelecka, T., Dorner, L.F., Schildkraut, I., and Aggarwal, A.K.
1997 Structure of the Multimodular Endonuclease FokI Bound to DNA. Nature Wah, D.A., Hirsch, J.A., Dorner, L.F., Schildkraut, I., Aggarwal, A.K.
2004 Structure of the Q237W mutant of HhaI DNA methyltransferase: An insight into protein-protein interactions. Biol Chem Dong, A., Zhou, L., Zhang, X., Stickel, S., Roberts, R.J.and Cheng, X.
2014 Structure of the Trehalose-6-phosphate Phosphatase from Brugia malayi Reveals Key Design Principles for Anthelmintic Drugs PLoS Pathog Farelli JD, Galvin BD, Li Z, Liu C, Aono M, Garland M, Hallett OE, Causey TB, Ali-Reynolds A, Saltzberg DJ, Carlow CK, Dunaway-Mariano D, Allen KN
2003 Structure of the large FK506-binding protein FKBP51, an Hsp90-binding protein and a component of steroid receptor complexes Proc Natl Acad Sci U S A Sinars, C.R., et al.
2014 Structure of the trehalose-6-phosphate phosphatase from Brugia malayi reveals a rational approach to the discovery of anthelmintic drugs PLoS�Pathog Farelli, J.D., Galvin, B.D., Li, Z., Liu, C., Aono, M., Garland, M., Hallett, O.E., Causey, T.B., Ali-Reynolds, A., Carlow, C.K.S., Dunaway-Mariano, D. and Allen, K.N.
2019 Structure, subunit organization and behavior of the asymmetric Type IIT restriction endonuclease BbvCI Nucleic Acids Res Shen, B.W., Doyle, L., Bradley, P., Heiter, D.F., Lunnen, K.D., Wilson, G.G., Stoddard, B.L.
2012 Structure-function analysis of Methanobacterium thermoautotrophicum RNA ligase - engineering a thermostable ATP independent enzyme BMC Mol Biol Zhelkovsky, A.M. and McReynolds, L.A.
1998 Structures of HhaI methyltransferase complexed with substrates containing mismatches at the target base. Nat Struct Biol O'Gara, M., Horton, J.R., Roberts, R.J.and Cheng, X.
1999 Structures of a Binary Complex of HhaI Methyltransferase with S-adenosyl-L-methionine Formed in the Presence of a Short Non-specific DNA Oligonucleotide. J Mol Biol O'Gara, M., Zhang, X., Roberts, R.J.and Cheng, X.