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We believe that basic research and the cultivation of scientific knowledge is critical for us to stay connected with our customers and to drive scientific breakthroughs. At NEB, over 30 labs participate in research projects, which are aided by post-doctoral fellows and students in Masters and Ph.D. programs. NEB researchers have authored or co-authored over 1,200 publications (as of 1/19) many of which are in peer-reviewed journals. Further, NEB products have been used successfully in numerous publications by scientists throughout the world.

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Year Title Journal Authors Application(s)
2001 Restriction enzyme BsoBI-DNA complex: a tunnel for recognition of degenerate DNA sequences and potential histidine catalysis. Structure van der Woerd, M.J., Pelletier, J.J., Xu, S.and Friedman, A.M.
2005 Crystal structure of the restriction-modification system control element C.BclI and mapping of its binding site. Structure Sawaya, M.R., Zhu, Z., Fana, M., Chan, S.H., Dabur, R., Xu, S.Y.and Balendiran, G.K.
2005 Implications for Switching Restriction Enzyme Specificities from the Structure of BstYI Bound to a BglII DNA Sequence Structure Townson, S.A., Samuelson, J.C., Xu, S.Y.and Aggarwal, A.K.
2010 Unusual target site disruption by the rare-cutting HNH restriction endonuclease PacI Structure Shen, B.W., Heiter, D.F., Chan, S.H., Wang, H., Xu, S.Y., Morgan, R.D., Wilson, G.G. and Stoddard, B.L.
2008 Structures of the rare-cutting restriction endonuclease NotI reveal a unique metal binding fold involved in DNA binding. Structure Lambert, A.R., Sussman, D., Shen, b., Maunus, R., Nix, J., Samuelson, J., Xu, S.Y.and Stoddard, B.L.
1995 Crystal structure of endo-beta-N-acetylglucosaminidase H at 1.9 A resolution: active-site geometry and substrate recognition. Structure Rao, V., Guan, C., and Van Roey, P.
2007 Selecting targeting of adenoviral vectors to neural precursor cells in the hippocampus of adult mice: new prospects for in situ gene therapy Stem Cells Schmidt, A. et al.
2016 High-efficiency generation of induced pluripotent mesenchymal stem cells from human dermal fibroblasts using recombinant proteins. Stem Cell Res Ther. Chen, F., Zhang, G., Yu, L., Feng, Y., Li, X., Zhang, Z., Wang, Y., Sun, D. and Pradhan, S.
2013 Prokaryotic super program advisory committee DOE Joint Genome Institute, Walnut Creek, CA, March 27, 2013 Stand Genomic Science Garrity, G.M. Banfield, J., Eisen, J., van der Lelie, N., McMahon, T., Rusch, D., Delong, E., Moran, M.A., Currie, C., Fuhrman, J., Hallam, S., Hugenholtz, P., Moran, N., Nelson, K., Roberts, R., Stepanauskas, R.
2010 Open source tool for prediction of genome wide protein-protein interaction network based on ortholog information. Source Code for Biology and Medicine Pedamallu, C.and Posfai, J.