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We believe that basic research and the cultivation of scientific knowledge is critical for us to stay connected with our customers and to drive scientific breakthroughs. At NEB, over 30 labs participate in research projects, which are aided by post-doctoral fellows and students in Masters and Ph.D. programs. NEB researchers have authored or co-authored over 1,200 publications (as of 1/19) many of which are in peer-reviewed journals. Further, NEB products have been used successfully in numerous publications by scientists throughout the world.

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Year Title Journal Authors Application(s)
2000 Structural Insights into the Protein Splicing Mechanism of PI-SceI. J.Biol.Chem. Poland, B.W., Xu, M.Q.and Quiocho, F.L.
2000 Protein trans-Splicing and Cyclization by a Naturally Split Intein from the dnaE Gene of Synechocystis Species PCC6803. J.Biol.Chem. Evans, T.C., Martin, D., Kolly, R., Panne, D., Sun, L., Ghosh, I., Chen, L., Benner, J., Liu, X-Q and Xu, M-Q
2000 InBase, the Intein Database. Nuc.Acids Res. Perler, F.B.
2000 A simple in vitro Tn7-based transposition system with low target site selectivity for genome and gene analysis. Nucl.Acids Res. Biery, M.C., Stewart, F.J., Stellwagen, A.E., Raleigh, E.A.and Craig, N.L.
2000 Expression and purification of recombinant proteins by fusion to maltose-binding protein. Mol.Biotechnol. Riggs, P.
2000 Methyl-specific DNA Binding by McrBC, a Modification-dependent Restriction Enzyme. J.Mol.Biol. Stewart, F.J., Panne, D., Bickle, T.A.and Raleigh, E.A.
2000 Protein Splicing in the Absence of an Intein Penultimate Histidine. J.Biol.Chem. Chen, L., Benner, J.and Perler, F.
2000 REBASE-restriction enzymes and methylases. Nucl.Acids Res. Roberts, R.J.and Macelis, D.
2000 Functional analysis of putative restriction-modification system genes in the Helicobacter pylori J99 genome. Nucl.Acids Res. Kong, H., Lin, L.F., Porter, N., Stickel, S.Byrd, D., Posfai, J.and Roberts R.J.
2000 Crystallization and preliminary X-ray diffraction analysis of MspI restriction endonuclease in complex with its cognate DNA. Acta Crystallogr.D.Biol.Crystallogr. O'Loughlin, T.J., Xu, Q., Kucera, R.B., Dorner, L.F., Sweeney, S., Schildkraut, I.and Guo, H.-C.