We believe that basic research and the cultivation of scientific knowledge is critical for us to stay connected with our customers and to drive scientific breakthroughs. At NEB, over 30 labs participate in research projects, which are aided by post-doctoral fellows and students in Masters and Ph.D. programs. NEB researchers have authored or co-authored over 1,000 publications (as of 1/17) many of which are in peer-reviewed journals. Further, NEB products have been used successfully in numerous publications by scientists throughout the world.

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    Basic Research

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Year Title Journal Authors Application(s)
2005 Crystal structure of the restriction-modification system control element C.BclI and mapping of its binding site. Structure Sawaya, M.R., Zhu, Z., Fana, M., Chan, S.H., Dabur, R., Xu, S.Y.and Balendiran, G.K.
1995 Crystal structure of endo-beta-N-acetylglucosaminidase H at 1.9 A resolution: active-site geometry and substrate recognition. Structure Rao, V., Guan, C., and Van Roey, P.
2010 Unusual target site disruption by the rare-cutting HNH restriction endonuclease PacI Structure Shen, B.W., Heiter, D.F., Chan, S.H., Wang, H., Xu, S.Y., Morgan, R.D., Wilson, G.G. and Stoddard, B.L.
1994 Structure of restriction endonuclease BamHI phased at 1.95 A resolution by MAD analysis. Structure Newman, M., Strzelecka, T., Dorner, L.F., Schildkraut, I., and Aggarwal, A.K.
2008 Structures of the rare-cutting restriction endonuclease NotI reveal a unique metal binding fold involved in DNA binding. Structure Lambert, A.R., Sussman, D., Shen, b., Maunus, R., Nix, J., Samuelson, J., Xu, S.Y.and Stoddard, B.L.
2016 Characterization of innate immunity genes in the parasitic nematode Brugia malayi Symbiosis Libro, S., Slatko, B.E. and Foster, J.M.
2010 The Wolbachia endosymbiont as an anti-filarial nematode target. Symbiosis Slatko, B.E., Taylor, M.J.& Foster, J.M.
2012 Targeted genome enrichment for efficient purification of endosymbiont DNA from host DNA Symbiosis Geniez, S., Foster, J.M., Kumar, S., Moumen, B., Leproust, E., Hardy, O., Guadalupe, M., Thomas, S.J., Boone, B., Hendrickson, C., Bouchon, D., Greve, P and Slatko, B.E.
2008 The symbiotic relationship between filarial parasitic nematodes and their wolbachia endosymbionts - a resource for a new generation of control measures. Symbiosis Ghedin, E., Daehnel, K., Foster, J., Slatko, B.and Lustigman S.
1998 Discovery and Uses of Novel Glycosidases Techniques in Glycobiology Wong-Madden, S.T., Landry, D., and Guthrie, E.P.