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We believe that basic research and the cultivation of scientific knowledge is critical for us to stay connected with our customers and to drive scientific breakthroughs. At NEB, over 30 labs participate in research projects, which are aided by post-doctoral fellows and students in Masters and Ph.D. programs. NEB researchers have authored or co-authored over 1,200 publications (as of 1/19) many of which are in peer-reviewed journals. Further, NEB products have been used successfully in numerous publications by scientists throughout the world.

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Year Title Journal Authors Application(s)
1987 Cloning, sequencing, in vivo promoter mapping, and expression in Escherichia coli of the gene for the HhaI methyltransferase. J.Biol.Chem. Caserta, M., Zacharias, W., Nwankwo, D., Wilson, G.G., and Wells, R.D.
2015 Accurate DNA Assembly and Genome Engineering with Optimied Uracil Excision Cloning ACS Synthetic Biology Cavaleiro, A.M., Kim, S.H., Seppälä, S., Nielsen, M.T., Nørholm, M.H.H.
2007 Catalytic domain of restriction endonuclease BmrI as a cleavage module for engineering endonucleases with novel substrate specificities. Nucl.Acids.Res. Chan, S-H, Boa, Y., Ciszak, E., Laget, S.and Xu, S-Y.
2010 Cofactor requirement of HpyAV restriction endonuclease. PLoS ONE Chan, S.H., Opitz, L., Higgins, L., O'loane, D.and Xu, S.Y.
2011 Natural and engineered nicking endonucleases--from cleavage mechanism to engineering of strand-specificity. Nucl.Acids.Res. Chan, S.H., Stoddard, B.L.and Xu, S.Y.
2004 Cloning of CviPII nicking and modification system from chlorella virus NYs-1 and application of Nt.CviPII in random DNA amplification. Nucl.Acids Res. Chan, S.H., Zhu, Z., Van Etten, J.L.and Xu, S.Y.
2006 Cloning of Nt.CviQII nicking endonuclease and its cognate methyltransferase: M.CviQII methylates AG sequences. Protein Expr.Purif. Chan, S.H., Zhu, Z., Van Etten, J.L.and Xu, S.Y.
2014 Myogenic differential methylation: diverse associations with chromatin structure Biology (Basel) Chandra S, Baribault C, Lacey M, Ehrlich M Epigenetics
2015 Tissue-specific epigenetics in gene neighborhoods: myogenic transcription factor genes Hum Mol Genet Chandra, S., Terragni, J., Zhang, G., Pradhan, S., Haushka, S., Johnston, D., Baribault, C., Lacey, M. and Ehrlich, M.
1988 Cloning and sequencing the HinfI restriction and modification genes. Gene Chandrasegaran, S., Lunnen, K.D., Smith, H.O., and Wilson, G.G.