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We believe that basic research and the cultivation of scientific knowledge is critical for us to stay connected with our customers and to drive scientific breakthroughs. At NEB, over 30 labs participate in research projects, which are aided by post-doctoral fellows and students in Masters and Ph.D. programs. NEB researchers have authored or co-authored over 1,200 publications (as of 1/19) many of which are in peer-reviewed journals. Further, NEB products have been used successfully in numerous publications by scientists throughout the world.

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Year Title Journal Authors Application(s)
2019 Non-destructive enzymatic deamination enables single molecule long read sequencing for the determination of 5-methylcytosine and 5-hydroxymethylcytosine at single base resolution. bioRxiv Sun Z, et al.
2019 EM-seq: Detection of DNA methylation at single base resolution from picograms of DNA. bioRxiv Vaisvila R, et al.
2019 Complete genome sequence of Escherichia coli BE104, an MC4100 drivative lacking the methionine reductive pathway Microbiol Resour Announc Anton, B.P., Morgan, R.D., Ezraty, B., Manta, B., Barras, F., Berkmen, M. Cloning & Synthetic Biology,DNA Assembly and Cloning,DNA Ligation,Golden Gate Assembly,Non-Cloning Ligation
2019 A ligand based system for receptor specific delivery of proteins Sci Rep Maffei, M., Morelli, C., Graham, E., Patriarca, S., Donzelli, L., Doleschall, B., de Castro, Reis, F., Nocchi, L., Chadick, C.H., Reymond, L., Correa, I.R., Jr., Johnsson, K., Hackett, J.A., Heppenstall, P.A Cellular Analysis,Cell Imaging,In vivo Imaging,CLIP Surface,SNAP Surface
2019 Human MettL3 MettL14 complex is a sequence specific DNA adenine methyltransferase active on single strand and unpaired DNA in vitro Cell Discov Woodcock, C.B.l, Yu, D., Hajian, T., Li, J., Huang, Y., Dai, N., Corrêa, I.R., Jr., Wu, T., Vedadi, M., Zhang, X., Cheng, X Epigenetics,DNA Methylation Analysis,Methylated DNA Analysis
2019 Platinum Sponsor Talk New options for methylome analysis and RNA depletion Journal of biomolecular techniques Stewart, F
2019 7 Deazaguanine modifications protect phage DNA from host restriction systems Nat Commun Hutinet, G., Kot, W., Cui, L., Hillebrand, R., Balamkundu, S., Gnanakalai, S., Neelakandan, R., Carstens, A.B., Fa Lui, C., Tremblay, D., Jacobs-Sera, D., Sassanfar, M., Lee, Y.J., Weigele, P., Moineau, S., Hatfull, G.F., Dedon, P.C., Hansen, L.H., de Crecy-Lagard, V
2020 Differential susceptibility of Onchocerca volvulus microfilaria to ivermectin in two areas of contrasting history of mass drug administration in Cameroon: relevance of microscopy and molecular techniques for the monitoring of skin microfilarial repopulation within six months of direct observed treatment BMC Infect Dis Abong, R.A., Amambo, G.N., Ndongmo, P.W.C., Njouendou, A.J., Manuel, R., Beng, A.A., Esum, M.E., Deribe, K., Fru-Cho, J., Fombad, F.F., Nji, T.M., Enyong, P.I., Poole, C.B., Pfarr, K., Hoerauf, A., Carlow, C.K.S., Wanji, S.
2020 Structural asymmetry governs the assembly and GTPase activity of McrBC restriction complexes Nat Commun Niu, Y., Suzuki, H., Hosford, C.J., Walz, T., Chappie, J.S.
2020 Visualization and sequencing of accessible chromatin reveals cell cycle and post-HDAC inhibitor treatment dynamics Journal of Molecular Biology Esteve, P.-O., Vishnu, U.S., Chin, H.G., Pradhan, S.