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We believe that basic research and the cultivation of scientific knowledge is critical for us to stay connected with our customers and to drive scientific breakthroughs. At NEB, over 30 labs participate in research projects, which are aided by post-doctoral fellows and students in Masters and Ph.D. programs. NEB researchers have authored or co-authored over 1,200 publications (as of 1/19) many of which are in peer-reviewed journals. Further, NEB products have been used successfully in numerous publications by scientists throughout the world.

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Year Title Journal Authors Application(s)
1998 FokI Dimerization is Required for DNA Cleavage. Proc.Natl.Acad.Sci.USA Bitinaite, J., Wah, D.A., Aggarwal, A.K., Schildkraut, I.
1998 Structure of FokI has Implications for DNA Cleavage. Proc.Natl.Acad.Sci.USA Wah, D.A., Bitinaite, J., Schildkraut, I., Aggarwal, A.K.
2002 Self-generated DNA termini relax the specificity of SgrAI restriction endonuclease. Proc.Natl.Acad.Sci.USA Bitinaite, J.and Schildkraut, I.
1994 Three-dimensional structure of the adenine-specific DNA methyltransferase M.Taq I in complex with the cofactor S-adenosylmethionine. Proc.Natl.Acad.Sci.USA Labahn, J., Granzin, J., Schluckebier, G., Robinson, D.P., Jack, W.E., Schildkraut, I., and Saenger, W.
2001 Comparative genomics of the restriction-modification systems in Helicobacter pylori. Proc.Natl.Acad.Sci.USA Lin, L.F., Posfai, J., Roberts, R.J.and Kong, H.
2001 Engineering a Nicking Endonuclease N.AlwI by Domain Swapping Proc.Natl.Acad.Sci.USA Xu, Y., Lunnen, K.and Kong, H.
1986 Cloning and comparison of repeated DNA sequences from the human filarial parasite Brugia malayi and the animal parasite Brugia pahangi. Proc.Natl.Acad.Sci.USA McReynolds, L.A., DeSimone, S.M., and Williams, S.A.
2009 The apearance of pyrrolysine in tRNAHis guanylyltransferase by neutral evolution. Proc.Natl.Acad.Sci.USA Heinemann, I.U., O'donoghue, P., Madinger, C., Benner, J., Randau, L., Noren, C.J.and Soll, D.
2000 Identification of type II restriction and modification systems in Helicobacter pylori reveals their substantial diversity among strains. Proc.Natl.Acad.Sci.USA Xu, Q., Morgan, R.D., Roberts, R.J.and Blaser, M.J.
1986 Escherichia coli K-12 restricts DNA containing 5-methylcytosine. Proc.Natl.Acad.Sci.USA Raleigh, E.A., and Wilson, G.