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We believe that basic research and the cultivation of scientific knowledge is critical for us to stay connected with our customers and to drive scientific breakthroughs. At NEB, over 30 labs participate in research projects, which are aided by post-doctoral fellows and students in Masters and Ph.D. programs. NEB researchers have authored or co-authored over 1,200 publications (as of 1/19) many of which are in peer-reviewed journals. Further, NEB products have been used successfully in numerous publications by scientists throughout the world.

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Year Title Journal Authors Application(s)
2017 High-throughput biochemical profiling reveals sequence determinants of dCas9 off-target binding and unbinding PNAS Evan A. Boyle, Johan O.L. Andreasson, Lauren M. Chircus, Samuel H. Sternberg, Michelle J. Wu, Chantal K. Guegler, Jennifer A. Doudna, and William J. Greenleaf
2016 A novel enrichment strategy reveals unprecedented number of novel transcription start sites at single base resolution in a model prokaryote and the gut microbiome. BMC Genomics Ettwiller, L., Buswell, J., Yigit, E. and Schildkraut, I
2011 A methylation and phosphorylation switch between an adjacent lysine and serine determines human DNMT1 stability. Nat Struct Mol Biol. Estève, P.O., Chang, Y., Samaranayake, M., Upadhyay, A.K., Horton, J.R., Feehery, G.R., Cheng, X.and Pradhan, S.
2014 Methyllysine reader plant homeodomain (PHD) finger protein 20-like 1 (PHF20L1) antagonizes DNA (cytosine-5) methyltransferase 1 (DNMT1) proteasomal degradation J Biol Chem Estève PO, Terragni J, Deepti K, Chin HG, Dai N, Espejo A, Corrêa IR Jr, Bedford MT, Pradhan S
2014 Methyllysine reader plant homeodomain (PHD) finger protein 20-like 1 (PHF20L1) antagonizes DNA (cytosine-5) methyltransferase 1 (DNMT1) proteasomal degradation J Biol Chem Estève PO
2016 Binding of 14-3-3 reader proteins to phosphorylated DNMT1 facilitates aberrant DNA methylation and gene expression Nucleic Acids Res Estève PO
2015 Binding of 14-3-3 reader proteins to phosphorylated DNMT1 facilitates Nucleic Acids Res Estève P., Zhang G., Ponnaluri V., Kanneganti Epigenetics
2009 Sequence-independent and reversible photocontrol of transcription/expression systems using a photosensitive nucleic acid binder Proc. Natl. Acad. Sci.  Estevez-Torres, A., Crozatier, C., Diguet, A., Hara, T., Saito, H., Yoshikawa, K., and Baigl, D.
2016 Binding of 14-3-3 reader proteins to phosphorylated DNMT1 facilitates aberrant DNA methylation and gene expression. Nucleic Acids Res. Esteve, P.O., Zhang, G., Ponnaluri, V.K., Deepti, K., Chin, H.G., Dai, N., Saqum, C., Black, K., Correa, I.R. Jr., Bedford, M.T., Cheng, X. and Pradhan, S.
2005 Functional analysis of the N- and C-terminus of mammalian G9a histone H3 methyltransferase. Nucl.Acids Res. Esteve, P.O., Patnaik, D., Chin, H.G., Benner, J., Teitell, M.A.and Pradhan, S.