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We believe that basic research and the cultivation of scientific knowledge is critical for us to stay connected with our customers and to drive scientific breakthroughs. At NEB, over 30 labs participate in research projects, which are aided by post-doctoral fellows and students in Masters and Ph.D. programs. NEB researchers have authored or co-authored over 1,200 publications (as of 1/19) many of which are in peer-reviewed journals. Further, NEB products have been used successfully in numerous publications by scientists throughout the world.

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Year Title Journal Authors Application(s)
2003 Assembly of high-affinity insulin receptor agonists and antagonists from peptide building blocks Proc. Natl. Acad. Sci. USA Schaffer, L., et al.
2003 Coevolution of an aminoacyl-tRNA synthetase with its tRNA substrates Proc. Natl. Acad. Sci. USA Salazar, J.C., et al.
2003 Covalent labeling of fusion proteins with chemical probes in living cells Chimia Gendreizig S. et al.
2003 Crystal structure of a mini-intein reveals a conserved catalytic module involved in side chain cyclization of asparagine during protein splicing. J.Biol.Chem. Ding, Y., Xu, M.-Q., Ghosh, I., Chen, X., Ferrandon, S., Lesage, G., Rao, Z.
2003 Cytosine methylation by the SuaI restriction-modification system: implications for genetic fidelity in a hyperthermophilic archaeon. J.Bacteriol. Grogan, D.W.
2003 Directed evolution of O6-alkylguanine-DNA alkyltransferase for efficient labeling of fusion proteins with small molecules in vivo Chem. Biol.  Juillerat A. et al.
2003 DNA -repair protein hHR23a alters its protein structure upon binding proteasomal subunit S5a Proc. Natl. Acad. Sci. USA Walters, K.J., et al.
2003 Covalent and selective immobilization of fusion proteins JACS Kindermann M. et al.
2003 Generation of an affinity column for antibody purification by intein-mediated protein ligation. J.Immunol.Methods Sun, L., Ghosh, I.and Xu, M.Q.
2003 Generation of the R2 subunit of ribonucleotide reductase by intein chemistry: insertion of 3-nitrotyrosine at residue 356 as a probe of the radical initiation process Biochemistry Yee, C.S., et al.