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We believe that basic research and the cultivation of scientific knowledge is critical for us to stay connected with our customers and to drive scientific breakthroughs. At NEB, over 30 labs participate in research projects, which are aided by post-doctoral fellows and students in Masters and Ph.D. programs. NEB researchers have authored or co-authored over 1,200 publications (as of 1/19) many of which are in peer-reviewed journals. Further, NEB products have been used successfully in numerous publications by scientists throughout the world.

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Year Title Journal Authors Application(s)
2004 Site-specific conjugation of oligonucleotides to the C-terminus of recombinant protein by expressed protein ligation Bioorg. Med. Chem. Lett. Takeda, S.,et al.
2004 Synthesis of fluorescently labeled mono- and diprenylated Rab7 GTPase J. Am. Chem. Soc. Durek, T., et al.
2004 Crystal Structure of BstYI at 1.85 Angstrom Resolution: A Thermophilic Restriction Endonuclease with Overlapping Specificities to BamHI and BglII. J.Molec.Biol. Townson, S.A., Samuelson, J.C., Vanamee, E.S., Edwards, T.A., Escalante, C.R., Xu, S.-Y.and Aggarwal, A.K.
2004 Changing the Enzymatic Activity of T7 Endonuclease by Mutations at the Beta-Bridge Site: Alteration of Substrate Specificity Profile and Metal Ion Requirements by Mutation Distant from the Catalytic Domain. Biochemistry Guan, C., Kumar, S., Kucera, R.and Ewel, A.
2004 Labeling of fusion proteins of O6-alkylguanine-DNA alkyltransferase with small molecules in vitro and in vivo Methods Keppler A. et al.
2004 In vitro semisynthesis and applications of C-terminally modified Rab proteins Methods Mol Biol. Durek T., Goody R.S and Alexandrov K.
2004 A genome sequence survey of the filarial nematode Brugia malayi: repeats, gene discovery, and comparative genomics. Mol.Biochem.Parasitol. Whitton, C., Daub, J., Quail, M., Hall, N., Foster, J., Ware, J., Ganatra, M., Slatko, B., Barrell, B.and Blaxter, M.
2004 Labeling of fusion proteins with synthetic fluorophores in live cells PNAS Keppler A. et al.
2004 Structure of the Q237W mutant of HhaI DNA methyltransferase: An insight into protein-protein interactions. Biol.Chem. Dong, A., Zhou, L., Zhang, X., Stickel, S., Roberts, R.J.and Cheng, X.
2004 Identifying protein function - a call for community action. PLoS Biology Roberts, R.J.