The Samuelson lab is primarily focused on tailoring E. coli strains and expression systems to maximize the expression and purification of individual proteins of interest.
NiCo21(DE3) is a BL21(DE3) derivative designed for improved expression and purification of His-tagged proteins.
Robichon, C., Luo, J., Causey, T.B., Benner, J.S.and Samuelson, J.C. (2011) Appl. Environ. Microbiol. 195-209 PMID: 21602383.