Small RNAs play a major role in the post-transcriptional regulation of gene expression. Though RNAi was initially discovered in nematodes and plants, RNA-mediated regulation is widely found in eukaryotic organisms, and similar small RNA guided regulatory pathways appear to be operative in prokaryotes. Eukaryotic small RNAs play critical roles in regulating gene expression in development, cancer biology, anti-viral defense and chromatin modification. Researchers have capitalized on regulatory pathways mediated by small RNAs to enable analyses of gene function not previously possible.
New England Biolabs continues its strong tradition of providing high quality reagents to support RNA research. Our expanding range of products includes tools for the synthesis, processing, transfection, isolation, analysis, amplification, copying and cloning of RNA molecules. In addition, we are committed to continually developing novel enzymatic tools and reagents, and putting them into the hands of scientists at the cutting edge of RNA research.