miRNA & siRNA

RNA Reagents

New England Biolabs provides many products useful for working with miRNA and siRNA.

RNA Ligases catalyze the ligation of nucleic acids through the formation of a 3'→5' phosphodiester bond. Substrates of these ligases include single-and double-stranded RNA and DNA, as well as dinucleoside pyrophosphates.

RNA ligases are routinely used for cloning and characterization of small RNAs. NEB supplies kits (NEB #E7330, NEB #E6120, NEB #E6160) containing adaptors, primers, enzymes and buffers that are ideal to convert small RNA into cDNA libraries for next-generation sequencing.

New England Biolabs supports RNA research by providing the tools necessary for synthesis, processing, transfection, detection, isolation, analysis, amplification and cloning of RNA molecules.

Featured Products

Reagents for RNA Sample Preparation

NEB offers a wide variety of reagents to facilitate front-end processing of RNA for downstream applications including next-generation sequencing, library construction and microarrays.

RNA Polymerase Selection Chart

NEB offers RNA polymerases that can be used for in vitro synthesis of RNA for a wide variety of downstream applications. Additional polymerases are offered for the generation of untemplated homoribopolymeric tails for reverse transcription or labeling.

RNA Ligase Selection Chart

NEB offers a variety of ligases for RNA research with unique specificities.

cDNA Synthesis Selection Chart

NEB offers several reagents for cDNA synthesis for use in applications including qPCR and qRT-PCR. For your convenience, reagents are available as kits or standalone products, depending on your needs.