- This product was discontinued on January 02, 2018
SET8 (PR-Set7) Methyltransferase mono-methylates lysine 20 of histone H4 (H4- K20) at the ε amino group of lysine residues (1). SET8-mediated histone H4 methylation is implicated in genome replication and stability (2).
- Supplied with 10x HMT Buffer and 32 mM S-adenosylmethionine (SAM)
SET8 (PR-Set7) Methyltransferase also plays an important role in the nodal pathways of embryo development (3).
Product SourceSET8 enzyme is expressed as an MBP fusion with human SET8 cDNA using an E. coli expression system.
The following reagents are supplied with this product:
Store at (°C) Concentration HMT Reaction Buffer 10 X S-adenosylmethionine (SAM) -20 32 mM
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