SET8 Methyltransferase

  • This product was discontinued on January 02, 2018
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SET8 (PR-Set7) Methyltransferase mono-methylates lysine 20 of histone H4 (H4- K20) at the ε amino group of lysine residues (1). SET8-mediated histone H4 methylation is implicated in genome replication and stability (2).

Ordering Information

  • Discontinued
  • Product Information
    SET8 (PR-Set7) Methyltransferase also plays an important role in the nodal pathways of embryo development (3).

    Product Source

    SET8 enzyme is expressed as an MBP fusion with human SET8 cDNA using an E. coli expression system.

    Reagents Supplied

    The following reagents are supplied with this product:

    Store at (°C) Concentration
    HMT Reaction Buffer 10 X
    S-adenosylmethionine (SAM) -20 32 mM
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