SET7 Methyltransferase methylates lysine 4 (Lys 4) of histone H3 (1). Methylation occurs at the ε amino group of lysine residues (2,3). Di- and tri- methylation of histone H3 Lys 4 is a hallmark of transcriptionally active chromatin (4,5).
- Supplied with 10x HMT Buffer and 32 mM S-adenosylmethionine (SAM)
Product SourceSET7 enzyme is expressed from human SET7 cDNA using an E. coli expression system using an MBP fusion tag.
The following reagents are supplied with this product:
Store at (°C) Concentration HMT Reaction Buffer -20 10 X S-adenosylmethionine (SAM) -20 32 mM
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