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  • E. coli K12 ER2508

    Limit of 1 per order. Although this product is free of charge, freight charges will apply. For US customers, available via phone ordering only (1-800-632-5227). For international customers, please contact your local NEB subsidiary or distributor.
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    Strain Products


    A suspension of E. coli strain ER2508 which has been grown in LB medium and brought to 50% glycerol.


    F- ara-14 leuB6 fhuA2 Δ(argF-lac)U169 lacY1 lon::miniTn10(TetR) glnV44 galK2 rpsL20(StrR) xyl-5 mtl-5 Δ(malB) zjc::Tn5(KanR) Δ(mcrC-mrr)HB101

    Properties and Usage

    Storage Temperature


    Antibiotic Resistance

    • kan
    • tetracycline
    • str

    Growth Media


    Growth Temperature

    37 °C


    1. This strain is a derivative of RR1 that has been made lon-. The lon mutation knocks out the major ATP-dependent protease in the E. coli cytoplasm, thus improving the stability of many foreign proteins when expressed in E. coli. The malE gene, which encodes Maltose-Binding Protein, is deleted as part of the malB deletion.
    2. This strain replaces PR745. It is fhuA2.


    1. Kowit, J.D. and Goldberg, A.L. (1977). J. Biol. Chem.. 252, 8350-8357.
    2. Grossman, A.D., Burgess, W.W. and Gross, C.A. (1983). Cell. 32, 151-159.

    Interactive Tools

    Safety Data Sheet

    The following is a list of Safety Data Sheet (SDS) that apply to this product to help you use it safely.