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DNA Repair Proteins

NEB carries a selection of  DNA repair enzymes for use in multiple applications:

  • Repair of DNA sample degradation due to oxidative damage, UV radiation, ionizing radiation, phenol/chloroform extraction, mechanical shearing, formalin fixation (post extraction) or long term storage
  • Base excision repair
  • DNA mismatch repair
  • Nucleotide excision repair
  • Forensic analysis of environmental samples, analysis of ancient DNA, DNA damage control, and DNA-DNA and protein-DNA interactions
  • Preparation for downstream applications such as PCR, microarray analysis, or other DNA technologies
  • Single cell gel electrophoresis (Comet assay) to assess samples for DNA damage
  • Genotoxicity tests by alkaline elution or alkaline unwinding
  • Manipulation of DNA supercoiling using DNA Gyrase (NEB #M0306) and Topoisomerase I (NEB #M0301)
  • Elimination or repair of large DNA secondary structures using T7 Endonuclease I (NEB #M0302)

Protocols for DNA Repair Proteins

    Publications related to DNA Repair Proteins

  1. Karbaschi, Mahsa., Macip, Salvador., Mistry, Vilas., Abbas, Hussein H.K., Delinassios, George J., Evans, Mark D., Young, Antony R., Cooke, Marcus S. 2015. Rescue of cells from apoptosis increases DNA repair in UVB exposed cells: implications for the DNA damage response Toxicol. Res.. 4, PubMedID: , DOI: doiL 10.1039/c4tx00197d

Properties of DNA Repair Enzymes

DNA Repair Glycosidases on Various Damaged Bases dsDNA

Legal Information

This product is covered by one or more patents, trademarks and/or copyrights owned or controlled by New England Biolabs, Inc (NEB).

While NEB develops and validates its products for various applications, the use of this product may require the buyer to obtain additional third party intellectual property rights for certain applications.

For more information about commercial rights, please contact NEB's Global Business Development team at gbd@neb.com.

This product is intended for research purposes only. This product is not intended to be used for therapeutic or diagnostic purposes in humans or animals.