FAQ: Can the Monarch HMW DNA Extraction Kits be used to process nematodes?

Yes. We have successfully isolated HMW DNA from C. elegans with the Monarch HMW DNA Extraction Kit for Tissue (NEB #T3060) using the standard protocol for tissue samples (worms from 2 plates were processed). We recommend using a rotor-stator homogenizer for sample homogenization for best yields.