FAQ: If I switch from Proteinase K, Molecular Biology Grade to Thermolabile Proteinase K, should I use the same amount of enzyme?

For most applications, the same volume of Thermolabile Proteinase K can be used in place of Proteinase K, Molecular Biology Grade. This is a good starting point; however, the exact amount of enzyme required may be substrate dependent and may need to be tested empirically.