HomeFAQsCan I omit the low-speed binding centrifugation step to save time?
FAQ: Can I omit the low-speed binding centrifugation step to save time?
You may omit this step if you wish and you will still get good results. However, results will be inconsistent, and depending on the starting material, yields may be reduced by 5-30%. Binding at low speed is particularly important for optimal recovery when processing tissue samples containing high amounts of DNA and when carrying out the Genomic DNA Cleanup Protocol.