FAQ: I used to purchase Nt.CviPII from NEB. The price and formulation appear to be different. Why?

Nt.CviPII was discontinued in November 2015 due to production issues. A recent publication (Ponnaluri V.K.C. et al. (2017) Genome Biol. 18: 122) describes NicE-Seq, a novel method for open chromatin profiling that utilizes Nt.CviPII. In order to manufacture Nt.CviPII at the level of quality that we expect for our restriction enzymes, the enzyme unit concentration as well as package price and size had to be adjusted.

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Nt.CviPII