FAQ: What do I do if I see a precipitate in the Ultra II FS Reaction Buffer?

It is not uncommon to see precipitation in the Ultra II FS Reaction Buffer. If this occurs, pipette the buffer several times to break up the precipitate, followed by a quick vortex to mix. You may still see a small amount of precipitation, but this will not affect performance.
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    Quick Tips - Preparing the NEBNext Ultra II FS DNA Reaction Buffer and Enzyme Mix

    Here are some important things to keep in mind when preparing the NEBNext® Ultra II FS DNA reaction buffer and enzyme mix for use.