FAQ: Can protein A magnetic beads (NEB# S1425S) be used to create Fc and Fab fragment pools after cleavage with IdeZ Protease?

Yes, Protein A magnetic beads (NEB# S1425S) can be used to create Fc and Fab fragment pools after cleavage with IdeZ Protease. The Fc fragment will bind to the beads and the Fab fragment will remain in the supernatant.