FAQ: What is the difference between the four Neuraminidase enzymes sold by NEB: α2-3,6,8 Neuraminidase, α2-3,6,8,9 Neuraminidase A, α2-3 Neuraminidase and α2-3 Neuraminidase S?

α2-3,6,8 Neuraminidase (NEB# P0720) is cloned from Clostridium perfringens and cleaves α2-3, α2-6 and α2-8 linked sialic acid residues.

α2-3,6,8,9 Neuraminidase A (NEB# P0722) is cloned from Arthrobacter ureafaciens and cleaves α2-3, α2-6, α2-8 and α2-9 linked sialic acid residues. It can also cleave branched sialic acid residues that are linked to an internal residue.

α2-3 Neuraminidase (NEB# P0728) is cloned from Salmonella typhimurium LT2 and cleaves α2-3 linked sialic acid residues.

α2-3 Neuraminidase S (NEB# P0743) is cloned from Streptococcus pneumoniae and cleaves α2-3 linked sialic acid residues.