FAQ: Has the conversion to the new buffer system altered any of the properties of the Restriction Enzyme itself?

The nature of the restriction enzymes is the same.  However, for a handful of enzymes, BSA enhances activity.  As a result, to keep the enzyme titer within specification for these products, the protein concentration may have been adjusted slightly. In addition, testing has revealed that BSA in the reaction buffer can stabilize the enzymes and make them more resistant to heat inactivation. 

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