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  • FAQ: Will Q5® High-Fidelity DNA Polymerase incorporate dUTPs?

    No. Q5 High-Fidelity DNA Polymerase will not incorporate dUTPs and is not compatible with USERTM cloning methods or bisulfite-treated DNA. For protocols employing bisulfite-treated DNA, we recommend EpiMark® Hot Start DNA Polymerase (NEB# M0490 ).