HomeFAQsIs PleI activity sensitive to dam, dcm or mammalian CpG methylation?
FAQ: Is PleI activity sensitive to dam, dcm or mammalian CpG methylation?
Yes. PleI may not be able to cut mammalian gDNA that contains some combinations of overlapping CpG methylation. For up-to-date information about methylation sensitivities, please visit Dam-Dcm and CpG Methylation or REBASE.