HomeFAQsDoes RNase R (NEB #M0100) have star activity?
FAQ: Does RNase R (NEB #M0100) have star activity?
Yes, adding a high concentration of RNase R to circular RNA samples can lead to circular RNA degradation. We recommend 1 unit of NEB RNase R per microgram of RNA (1:1 ratio) to prevent star activity.
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