FAQ: What is the difference between the NEBNext^® Enzymatic Methyl-seq v2 Kit (NEB #E8015) and the original NEBNext Enzymatic Methyl-seq Kit (NEB #E7120)?

The NEBNext Enzymatic Methyl-seq v2 Kit has a broader input range (100 pg - 200 ng) and a faster, more streamlined workflow that reduces consumables use. 

Overall data quality is improved, with higher yields and lower duplication rates resulting in increased CpG coverage levels across a wider input range.