HomeFAQsCan components from the older Monarch® Plasmid Miniprep Kit (NEB #T1010) be used interchangeably with those from the new version of the kit (Monarch Spin Plasmid Miniprep Kit, NEB #T1110)?
FAQ: Can components from the older Monarch® Plasmid Miniprep Kit (NEB #T1010) be used interchangeably with those from the new version of the kit (Monarch Spin Plasmid Miniprep Kit, NEB #T1110)?
Yes, while the new version of the Monarch Spin Plasmid Miniprep Kit is developed with improvements to both the physical column and buffer chemistry, the previous version's components are compatible with the updated kit. The purified plasmid DNA will remain high-quality, suitable for various downstream applications; however, there may be up to 20% variances in yield in some cases.
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