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  • DNA Modification

    New England Biolabs offers a wide range of reagents that facilitate DNA modification or repair for downstream cloning, amplification, labeling or sequencing applications. We also offer modifying enzymes that can be used to study the effect of DNA methylation on genetic expression.

    DNA Modification

    DNA Nicking

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    OrderTma Endonuclease III

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    OrderTth Endonuclease IV

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    OrderAPE 1

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    OrderCutSmart™ Buffer

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    OrderDiluent A

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    OrderDiluent B

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    OrderEndonuclease IV

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    OrderEndonuclease V

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    OrderEndonuclease VIII

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    OrderFpg

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    OrderhOGG1

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    OrderLambda DNA (N6-methyladenine-free)

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    OrderNb.BbvCI

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    OrderNb.BsmI

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    OrderNb.BtsI

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    OrderNEBuffer 1

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    OrderNEBuffer 1.1

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    OrderNEBuffer 2

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    OrderNEBuffer 2.1

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    OrderNEBuffer 3

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    OrderNEBuffer 3.1

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    OrderNEBuffer 4

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    OrderNEBuffer EcoRI

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    OrderNEBuffer Set 1.1, 2.1, 3.1 and CutSmart

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    OrderNt.AlwI

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    OrderNt.BbvCI

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    OrderNt.BsmAI

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    OrderNt.BspQI

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    OrderNt.BstNBI

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    OrderNt.CviPII

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    OrderSspI

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    OrderT4 PDG (T4 Endonuclease V)

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    OrderT7 Endonuclease I

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    OrderUSER™ Enzyme

    DNA End Treating

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    OrderAlkaline Phosphatase, Calf Intestinal (CIP)

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    OrderAmylose Magnetic Beads

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    OrderAntarctic Phosphatase

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    OrderAntarctic Phosphatase Reaction Buffer

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    Biotinylated Alkaline Phosphatase

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    OrderDeoxynucleotide (dNTP) Solution Mix

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    OrderDeoxynucleotide (dNTP) Solution Set

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    OrderDNA Polymerase I, Large (Klenow) Fragment

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    OrderExonuclease I Reaction Buffer

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    OrderExonuclease T

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    OrderFspI

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    OrderHpaI

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    OrderLambda DNA

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    OrderLambda DNA (N6-methyladenine-free)

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    OrderM13mp18 RF I DNA

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    OrderMung Bean Nuclease

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    OrderNEBNext® End Repair Module

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    OrderPhusion® High-Fidelity DNA Polymerase

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    OrderPhusion® High-Fidelity PCR Master Mix with GC Buffer

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    OrderPhusion® High-Fidelity PCR Master Mix with HF Buffer

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    Orderp-Nitrophenyl Phosphate (PNPP)

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    OrderPsiI

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    OrderQuick Blunting™ and Quick Ligation™ Kits

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    OrderQuick Blunting™ Kit

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    OrderRecJf

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    OrderShrimp Alkaline Phosphatase (rSAP)

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    OrderT4 DNA Ligase Reaction Buffer

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    OrderT4 DNA Polymerase

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    OrderT4 Polynucleotide Kinase

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    OrderT4 Polynucleotide Kinase (3' phosphatase minus)

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    OrderT4 Polynucleotide Kinase Reaction Buffer

    DNA Repair

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    Orderβ-Nicotinamide adenine dinucleotide (NAD+)

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    OrderAfu Uracil-DNA Glycosylase (UDG)

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    OrderSulfolobus DNA Polymerase IV

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    OrderTma Endonuclease III

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    OrderTth Endonuclease IV

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    Order5-methyl-dCTP

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    OrderAntarctic Thermolabile UDG

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    OrderAPE 1

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    OrderDeoxynucleotide (dNTP) Solution Mix

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    OrderDeoxynucleotide (dNTP) Solution Set

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    OrderEndonuclease III (Nth)

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    OrderEndonuclease IV

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    OrderEndonuclease V

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    OrderEndonuclease VIII

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    OrderFpg

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    OrderhAAG

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    OrderhOGG1

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    OrderhSMUG1

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    OrderPreCR® Repair Mix

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    OrderRecA

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    OrderRecAf

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    OrderT4 PDG (T4 Endonuclease V)

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    OrderT7 Endonuclease I

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    OrderUDG Reaction Buffer

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    OrderUracil Glycosylase Inhibitor (UGI)

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    OrderUracil-DNA Glycosylase (UDG)

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    OrderUSER™ Enzyme

    DNA & Protein Methylation

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    Orderdam Methyltransferase

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    OrderTaqI Methyltransferase

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    OrderAluI Methyltransferase

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    OrderBamHI Methyltransferase

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    OrderCpG Methyltransferase (M.SssI)

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    OrderEcoRI Methyltransferase

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    OrderEpiMark® Nucleosome Assembly Kit

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    OrderG9a Methyltransferase

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    OrderGpC Methyltransferase (M.CviPI)

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    OrderHaelll Methyltransferase

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    OrderHhal Methyltransferase

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    OrderHistone H10 Human, Recombinant

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    OrderHistone H2A Human, Recombinant

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    OrderHistone H2A/H2B Dimer Human, Recombinant

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    OrderHistone H2B Human, Recombinant

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    OrderHistone H3.1 Human, Recombinant

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    OrderHistone H3.1/H4 Tetramer Human, Recombinant

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    OrderHistone H3.2 Human, Recombinant

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    OrderHistone H3.3 Human, Recombinant

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    OrderHistone H4 Human, Recombinant

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    OrderHpaII Methyltransferase

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    OrderMspI Methyltransferase

    DNA Ligation

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    OrderThermostable 5´ AppDNA/RNA Ligase

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    OrderE. coli DNA Ligase

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    OrderTaq DNA Ligase

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    OrderTaq DNA Ligase Reaction Buffer

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    Order9°N™ DNA Ligase

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    OrderBlunt/TA Ligase Master Mix

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    OrderInstant Sticky-end Ligase Master Mix

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    OrderNEB 5-alpha Electrocompetent E. coli

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    OrderNEBNext® Multiplex Oligos for Illumina® (Index Primers Set 1)

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    OrderNEBNext® Multiplex Oligos for Illumina® (Methylated Adaptor, Index Primers Set 1)

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    OrderNEBNext® Quick Ligation Module

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    OrderNEBNext® Ultra™ Ligation Module

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    OrderpSV40-GLuc Control Plasmid

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    OrderQuick Blunting™ and Quick Ligation™ Kits

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    OrderQuick Blunting™ Kit

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    OrderT3 DNA Ligase

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    OrderT4 DNA Ligase

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    OrderT4 DNA Ligase Reaction Buffer

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    OrderT7 DNA Ligase

    DNA Nicking

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    OrderTma Endonuclease III

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    OrderTth Endonuclease IV

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    OrderAPE 1

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    OrderCutSmart™ Buffer

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    OrderDiluent A

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    OrderDiluent B

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    OrderEndonuclease IV

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    OrderEndonuclease V

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    OrderEndonuclease VIII

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    OrderFpg

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    OrderhOGG1

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    OrderLambda DNA (N6-methyladenine-free)

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    OrderNb.BbvCI

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    OrderNb.BsmI

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    OrderNb.BtsI

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    OrderNEBuffer 1

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    OrderNEBuffer 1.1

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    OrderNEBuffer 2

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    OrderNEBuffer 2.1

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    OrderNEBuffer 3

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    OrderNEBuffer 3.1

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    OrderNEBuffer 4

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    OrderNEBuffer EcoRI

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    OrderNEBuffer Set 1.1, 2.1, 3.1 and CutSmart

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    OrderNt.AlwI

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    OrderNt.BbvCI

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    OrderNt.BsmAI

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    OrderNt.BspQI

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    OrderNt.BstNBI

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    OrderNt.CviPII

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    OrderSspI

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    OrderT4 PDG (T4 Endonuclease V)

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    OrderT7 Endonuclease I

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    OrderUSER™ Enzyme

    DNA End Treating

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    OrderDeoxynucleotide (dNTP) Solution Mix

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    OrderDeoxynucleotide (dNTP) Solution Set

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    OrderExonuclease I Reaction Buffer

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    OrderExonuclease T

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    OrderNEBNext® End Repair Module

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    OrderRecJf

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    OrderT4 Polynucleotide Kinase

    DNA Blunting

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    OrderAlkaline Phosphatase, Calf Intestinal (CIP)

    Close

    OrderAmylose Magnetic Beads

    Close

    OrderDNA Polymerase I, Large (Klenow) Fragment

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    OrderFspI

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    OrderHpaI

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    OrderLambda DNA

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    OrderLambda DNA (N6-methyladenine-free)

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    OrderM13mp18 RF I DNA

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    OrderMung Bean Nuclease

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    OrderPhusion® High-Fidelity DNA Polymerase

    Close

    OrderPhusion® High-Fidelity PCR Master Mix with GC Buffer

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    OrderPhusion® High-Fidelity PCR Master Mix with HF Buffer

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    OrderPsiI

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    OrderQuick Blunting™ and Quick Ligation™ Kits

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    OrderQuick Blunting™ Kit

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    OrderT4 DNA Polymerase

    DNA Phosphorylation

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    OrderQuick Blunting™ and Quick Ligation™ Kits

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    OrderQuick Blunting™ Kit

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    OrderT4 DNA Ligase Reaction Buffer

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    OrderT4 Polynucleotide Kinase (3' phosphatase minus)

    DNA Dephosphorylation

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    OrderAlkaline Phosphatase, Calf Intestinal (CIP)

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    OrderAntarctic Phosphatase

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    OrderAntarctic Phosphatase Reaction Buffer

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    Biotinylated Alkaline Phosphatase

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    OrderLambda DNA

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    OrderLambda DNA (N6-methyladenine-free)

    Close

    OrderM13mp18 RF I DNA

    Close

    Orderp-Nitrophenyl Phosphate (PNPP)

    Close

    OrderShrimp Alkaline Phosphatase (rSAP)

    Close

    OrderT4 Polynucleotide Kinase Reaction Buffer

    DNA Repair

    Close

    Orderβ-Nicotinamide adenine dinucleotide (NAD+)

    Close

    OrderAfu Uracil-DNA Glycosylase (UDG)

    Close

    OrderSulfolobus DNA Polymerase IV

    Close

    OrderTma Endonuclease III

    Close

    OrderTth Endonuclease IV

    Close

    Order5-methyl-dCTP

    Close

    OrderAntarctic Thermolabile UDG

    Close

    OrderAPE 1

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    OrderDeoxynucleotide (dNTP) Solution Mix

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    OrderDeoxynucleotide (dNTP) Solution Set

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    OrderEndonuclease III (Nth)

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    OrderEndonuclease IV

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    OrderEndonuclease V

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    OrderEndonuclease VIII

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    OrderFpg

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    OrderhAAG

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    OrderhOGG1

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    OrderhSMUG1

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    OrderPreCR® Repair Mix

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    OrderRecA

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    OrderRecAf

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    OrderT4 PDG (T4 Endonuclease V)

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    OrderT7 Endonuclease I

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    OrderUDG Reaction Buffer

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    OrderUracil Glycosylase Inhibitor (UGI)

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    OrderUracil-DNA Glycosylase (UDG)

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    OrderUSER™ Enzyme

    DNA & Protein Methylation

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    Orderdam Methyltransferase

    Close

    OrderTaqI Methyltransferase

    Close

    OrderAluI Methyltransferase

    Close

    OrderBamHI Methyltransferase

    Close

    OrderCpG Methyltransferase (M.SssI)

    Close

    OrderEcoRI Methyltransferase

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    OrderEpiMark® Nucleosome Assembly Kit

    Close

    OrderG9a Methyltransferase

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    OrderGpC Methyltransferase (M.CviPI)

    Close

    OrderHaelll Methyltransferase

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    OrderHhal Methyltransferase

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    OrderHistone H10 Human, Recombinant

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    OrderHistone H2A Human, Recombinant

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    OrderHistone H2A/H2B Dimer Human, Recombinant

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    OrderHistone H2B Human, Recombinant

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    OrderHistone H3.1 Human, Recombinant

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    OrderHistone H3.1/H4 Tetramer Human, Recombinant

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    OrderHistone H3.2 Human, Recombinant

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    OrderHistone H3.3 Human, Recombinant

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    OrderHistone H4 Human, Recombinant

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    OrderHpaII Methyltransferase

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    OrderMspI Methyltransferase

    DNA Ligation

    Close

    OrderThermostable 5´ AppDNA/RNA Ligase

    Close

    OrderE. coli DNA Ligase

    Close

    OrderTaq DNA Ligase

    Close

    OrderTaq DNA Ligase Reaction Buffer

    Close

    Order9°N™ DNA Ligase

    Close

    OrderBlunt/TA Ligase Master Mix

    Close

    OrderInstant Sticky-end Ligase Master Mix

    Close

    OrderNEB 5-alpha Electrocompetent E. coli

    Close

    OrderNEBNext® Multiplex Oligos for Illumina® (Index Primers Set 1)

    Close

    OrderNEBNext® Multiplex Oligos for Illumina® (Methylated Adaptor, Index Primers Set 1)

    Close

    OrderNEBNext® Quick Ligation Module

    Close

    OrderNEBNext® Ultra™ Ligation Module

    Close

    OrderpSV40-GLuc Control Plasmid

    Close

    OrderQuick Blunting™ and Quick Ligation™ Kits

    Close

    OrderQuick Blunting™ Kit

    Close

    OrderT3 DNA Ligase

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    OrderT4 DNA Ligase

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    OrderT4 DNA Ligase Reaction Buffer

    Close

    OrderT7 DNA Ligase

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