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  • Abraham, D., Eberhard, M.L., Lange, A.M., Yutanawiboonchai, W., Perler, F.B. and Lok, J.B. (1992) Identification of surrogate rodent hosts for larval Onchocerca lienalis and induction of protective immunity in a model system. J Parasitol. 78: 447-453.PubMed ID:1597787
  • Adam, E. and Perler, F.B. (2002). Development of a Positive Genetic Selection System for Inhibition of Protein Splicing Using Mycobacterial Inteins in Escherichia coli DNA Gyrase Subunit A. J. Mol. Micro. Biotechnol. 4:479-487.PubMed ID:12432958
  • Adams, M.W.W., Perler, F.B. and Kelly, R.M. (1995). Extremozymes: expanding the limits of biocatalysis. Biotechnology 13: 662-668.PubMed ID:9546220
  • Aliotta, J. M., Pelletier, J. J., Ware, J. L., Moran, L. S., Benner, J. S., and Kong, H. (1996). Thermostable Bst DNA polymerase I lacks a 3' fwdarw 5' proofreading exonuclease activity1. Genetic Analysis Biomolecular Engineering 12:185-195.PubMed ID:8740835
  • Anton, B. P., Heiter, D. F., Benner, J. S., Hess, E. J., Greenough, L., Moran, L. S., Slatko, B. E., and Brooks, J. E. (1997). Cloning and characterization of the BglII restriction-modification system reveals a possible evolutionary footprint. Gene 187:19-27.PubMed ID:9073062
  • Arasu, P., and Perler, F. B. (1987). Genomic Cloning of Recombinant Antigens Detected by Antiserum Against Infective Larvae of Brugia Malayi. Molecular Paradigms for Eradicating Helminthic Parasites, pp. 183-192.
  • Arasu, P., Nutman, T. B., Steel, C., Mulligan, M. M., Abraham, D., Tuan, R. S., and Perler, F. B. (1989). Human T-cell stimulation, molecular characterization and in situ mRNA localization of a Brugia malayi recombinant antigen. Mol. Biochem. Parasitol. 36:223-231.PubMed ID:2797061
  • Arasu , P., Philipp, M., and Perler, F. (1987). Brugia malayi: recombinant antigens expressed by genomic DNA clones. Exp. Parasitol. 64:281-291.PubMed ID:2824231
  • Awobuluyi, M., Mania, C. V., and Carlow, C. K. S. (1991). Cross-linking of a monoclonal antibody-antigen complex enables detection of parasite antigen in immunoblots and in an expression library. Mol. Biochem. Parasitol. 44:149-152.PubMed ID:1707139
  • Bacolla, A., Pradhan, S., Roberts, R.J. and Wells, R.D. (1999). Recombinant Human DNA (Cytosine-5) Methyltransferase. II. steady-state kinetics reveal allostericactivation by methylated DNA. J. Biol. Chem. 274:33011-33019.PubMed ID:10551869
  • Bacolla, A., Pradhan, S., Larson, J.E., Roberts, R.J. and Wells, R.D. (2001). Recombinant human DNA (cytosine-5) methyltransferase. III. Allosteric control, reaction order, and influence of plasmid topology and triplet repeat length on methylation of the fragile X CGGCCG sequence. J. Biol. Chem. 276:18605-18613.PubMed ID:11359795
  • Baldwin, G. S., Kelly, S. M., Price, N. C., Wilson, G. G., Connolly, B. A., Artymiuk, P. J., and Hornby, D. P. (1994). Ligand-induced conformational states of the cytosine-specific DNA methyltransferase M.HgaI-2. J. Mol. Biol. 235:545-553.PubMed ID:8289281
  • Balendiran, K., Bonventre, J., Knott, R., Jack, W., Benner, J., Schildkraut, I., and Anderson, J. E. (1994). Expression, purification, and crystallization of restriction endonuclease PvuII with DNA containing its recognition site. Proteins 19:77-79.PubMed ID:8066089
  • Bandi, C., Slatko, B. and O'Neill, S.L. (1999). Wolbachia genomes and the many faces of symbiosis. Parasitology Today 15(11):428-429.
  • Barany, F., Slatko, B., Danzitz, M., Cowburn, D., Schildkraut, I., and Wilson, G. G. (1992). The corrected nucleotide sequences of the TaqI restriction and modification enzymes reveal a thirteen-codon overlap. Gene 112:91-95.PubMed ID:1551592
  • Barnwell, J.W., Galinski, M.R., DeSimone, S.G., Perler, F. and Ingravallo, P. (1999). Plasmodium vivax, P. cynomolgi, and P. knowlesi: Identification of Homologue Proteins Associated with the Surface of Merozoites. Exp. Parasitol. 91:238-249. PubMed ID:10072326
  • Barsomian, J. M., Card, C. O., and Wilson, G. G. (1988). Cloning of the HhaI and HinPI restriction-modification systems. Gene 74:5-7.PubMed ID:3074013
  • Belfort, M., and Roberts, R. J. (1997). Homing endonucleases: keeping the house in order. Nucl. Acids Res. 25:3379-3388.PubMed ID:9254693
  • Besnier, C.E. and Kong, H. (2001). Converting MlyI endonuclease into a nicking enzyme by changing its oligomerization state. EMBO Reports 2(9):782-786.PubMed ID:11520857
  • Bestul, K.J., McCall, J. W., Supakorndej, N., Ma, D., Carlow, C. K. S. (1998). Evaluation of the ASSURE/FH Antibody Assay for the Detection of Feline Heartworm Infection. Proc. Amer. Heartworm Symp. (In press).
  • Biery, M.C., Stewart, F.J., Stellwagen, A.E., Raleigh, E.A. and Craig, N.L. (2000). A simple in vitro Tn7-based transposition system with low target site selectivity for genome and gene analysis. Nucl. Acids Res. 28(5):1067-1077.PubMed ID:10666445
  • Bitinaite, J., Wah, D. A., Aggarwal, A. K., Schildkraut, I. (1998). FokI Dimerization is Required for DNA Cleavage. Proc. Natl. Acad. Sci. USA 95(18):10570-10575.PubMed ID:9724744
  • Bitinaite, J. and Schildkraut, I. (2002). Self-generated DNA termini relax the specificity of SgrAI restriction endonuclease. Proc. Natl. Acad. Sci. USA 99(3):1164-1169.PubMed ID:11818524
  • Blaxter, M. L., Raghavan, N., Ghosh, I., Guiliano, D., Lu, W., Williams, S. A., Slatko, B. and Scott, A. L. (1996). Genes expressed in Brugia malayi infective third stage larvae. Molecular and Biochemical Parasitology 77:77-93.PubMed ID:8784774
  • Blaxter, M., Aslett, M., Guiliano, D., Daub, J. and The Filarial Genome Project (1999). Parasitic helminth genomics. Exp. Parasitology118:S39-S51.PubMed ID:10466136
  • Bonventre, J., Walsh, P. and Robinson, D., Molecular Biology Problem Solver: A Laboratory Guide, (A.S. Gerstein, Ed.), Chapter 9, J. Wiley Publishers, 2001.
  • Bradley, J. E., Trenholme, K. R., Gillespie, A. J., Guderian, R., Titanji, V., Hong, Y., and McReynolds, L. (1993). A sensitive serodiagnostic test for onchocerciasis using a cocktail of recombinant antigens. Am J Trop Med Hyg. 48:198-204.PubMed ID:8447523
  • Brooks, J. E. (1987). Properties and uses of restriction endonucleases. Methods Enzymol. 152:113-129.PubMed ID:2821353
  • Brooks, J. E., Benner, J. S., Heiter, D. F., Silber, K. R., Sznyter, L. A., Jager-Quinton, T., Moran, L. S., Slatko, B. E., Wilson, G. G., and Nwankwo, D. O. (1989). Cloning the BamHI restriction modification system. Nucl. Acids Res. 17:979-997.PubMed ID:2537955
  • Brooks, J. E., Nathan, P. D., Landry, D., Sznyter, L. A., Waite-Rees, P., Ives, C. L., Moran, L. S., Slatko, B. E., and Benner, J. S. (1991). Characterization of the cloned BamHI restriction modification system: its nucleotide sequence, properties of the methylase, and expression in heterologous hosts. Nucl. Acids Res. 19:841-850.PubMed ID:1901989
  • Cantor, E.J. and Chong, S. (2001). Intein-mediated rapid purification of cre recombinase. Protein Expr. Purif. 22(1):135-140.PubMed ID:11388811
  • Card, C. O., Williams, S. A., Moran, L. S., Poole, C. B., and Slatko, B. E. (1987). The Use of DNA Sequencing Reactions as Probes for Southern Blots, Dot Blots and Colony Hydridizations. BioTechniques 5:302-307.
  • Card, C. O., Wilson, G. G., Weule, K., Hasapes, J., Kiss, A., and Roberts, R. J. (1990). Cloning and characterization of the HpaII methylase gene. Nucl. Acids Res. 18:1377-1383.PubMed ID:2183189
  • Carlow, C. K. S., Edwards, M. K., James, E. R., and Philipp, M. (1987). Monoclonal antibodies to parasite antigens: a rapid immunization protocol requiring small numbers of parasites. J. Parasitol. 73:1054-1057.PubMed ID:3309239
  • Carlow, C. K. S., Franke, E. D., Lowrie, R. C. J., Partono, F., and Philipp, M. (1987). Monoclonal antibody to a unique surface epitope of the human filaria Brugia malayi identifies infective larvae in mosquito vectors. Proc. Natl. Acad. Sci. USA 84:6914-6918.PubMed ID:2443912
  • Carlow, C. K. S., Perrone, J., Spielman, A., and Philipp, M. A. (1987). A Developmentally regulated surface epitope expressed by the infective larva of Brugia malayi which is rapidly lost after infection. Alan R. Liss, Inc., Molecular Paradigms for Eradicating Helmenthic Parasites,, 301-310.
  • Carlow, C. K. S., and Philipp, M. (1987). Protective immunity to Brugia malayi larvae in BALB/c mice: potential of this model for the identification of protective antigens. Am. J . Trop. Med. Hyg. 37:597-604.PubMed ID:3688312
  • Carlow, C. K. S., Busto, P., Storey, N., and Philipp, M. (1990). Anti-idiotypic antibodies function as a surrogate surface epitope of Brugia malayi infective larvae. Acta Trop., 47:391-397.PubMed ID:1700584
  • Carlow, C. K. S., Suwita, A., Bahang, Z., Purnomo, Partono, F., and Philipp, M. (1990). Field testing of monoclonal probe specific for infective larvae of human Brugian parasites. Wiley-Liss, Inc. Parasites: Molecular Biology, Drug and Vaccine Design. 479-488.
  • Carroll, R.S., Zhang, J., Bello, L., Melnick, M.B., Maruyama, T. and Black, P.M. (1999). KDR Activation in Astrocytic Neoplasms. Cancer 86(7):1335-1341.
  • Caserta, M., Zacharias, W., Nwankwo, D., Wilson, G. G., and Wells, R. D. (1987). Cloning, sequencing, in vivo promoter mapping, and expression in Escherichia coli of the gene for the HhaI methyltransferase. J. Biol. Chem. 262:4770-4777.PubMed ID:3549710
  • Chandrasegaran, S., Lunnen, K. D., Smith, H. O., and Wilson, G. G. (1988). Cloning and sequencing the HinfI restriction and modification genes. Gene 70:387-392.PubMed ID:3063606
  • Chen Z. and Kong, H. (1988). Isolation and characterization of restriction endonuclease BstYI from Bacillus stearothermophilus. FEBS Lett. 234:169-171.PubMed ID:2839359
  • Chen Z., Kong, H. and Wang, L. (1989). Isolation and characterization of restriction endonuclease BstFI and BstSI from Bacillus stearothermophilus. J. Fudan Univ. Natural Sci. 28:363-366.
  • Chen, L., Benner, J. and Perler, F. (2000). Protein Splicing in the Absence of an Intein Penultimate Histidine. J. Biol. Chem. 275(27):20431-20435.PubMed ID:10770923
  • Chen, L., Pradhan, S. and Evans, T.C. Jr. (2001). Herbicide resistance from a divided EPSPS protein: the split Synechocystis DnaE intein as an in vivo affinity domain. Gene 263(1-2):39-48.PubMed ID:11223241
  • Chen, X., Xu, M.-Q., Ding, Y., Ferrandon, S. and Rao, Z. (2002). Purification and initial crystallization studies of a DnaB intein from Synechocystis sp. PCC 6803. Acta Crystallogr. D. Biol. Crystallogr. 58(Pt 7):1201-1203.PubMed ID:12077443
  • Chen, X., Xu, M.-Q., Ding, Y., Ferrandon, S. and Rao, Z. (2002A). Crystallographic study of a naturally occurring trans-splicing intein from Synechocystis sp. PCC 6803. Acta Crystallogr. D. Biol. Crystallogr. 58(Pt 7):1204-1206.PubMed ID:12077444
  • Cheng, X., Kumar, S., Posfai, J., Pflugrath, J. W., and Roberts, R. J. (1993). Crystal structure of the HhaI DNA methyltransferase complexed with S-adenosyl-L-methionine. Cell 74:299-307.PubMed ID:8343957
  • Cheng, X., Kumar, S., Klimasauskas, S., and Roberts, R. J. (1993). Crystal Structure of the HhaI DNA Methyltransferase. Cold Spring Harbor Laboratory Press, 331-338.PubMed ID:7956046
  • Cheng, X., Balendiran, K., Schildkraut, I., and Anderson, J. E. (1994). Structure of PvuII endonuclease with cognate DNA. EMBO J. 13:3927-3935.PubMed ID:8076590
  • Cheng, X., Balendiran, K., Schildkraut, I., and Anderson, J. E. (1995). Crystal structure of the PvuII restriction endonuclease. Gene 157:139-140.PubMed ID:7607478
  • Cheng, X. and Roberts, R.J. (2001). AdoMet-dependent methylation, DNA methyltransferases and base flipping. Nucl. Acids Res. 29:3784-3795.PubMed ID:11557810
  • Chin, H.G., Kim, G.D., Marin, I., Mersha, F., Evans, T.C. Jr., Chen, L., Xu, M.-Q. and Pradhan, S. (2003). Protein trans-splicing in transgenic plant chloroplast: Reconstruction of herbicide resistance from split genes. Proc. Natl. Acad. Sci. USA 100(8):4510-4515.PubMed ID:12671070
  • Chong, S., Shao, Y., Paulus, H., Benner, J., Perler, F. B., and Xu, M. Q. (1996). Protein splicing involving the Saccharomyces cerevisiae VMA intein. The steps in the splicing pathway, side reactions leading to protein cleavage, and establishment of an in vitro splicing system. J. Biol. Chem. 271:22159-22168.PubMed ID:8703028
  • Chong, S., and Xu, M. Q. (1997). Protein Splicing of the Saccharomyces cerevisiae VMA Intein without the Endonuclease Motifs*. J Biol. Chem. 272:15587-15590.PubMed ID:9188443
  • Chong, S., Mersha, F. B., Comb, D. G., Scott, M. E., Landry, D., Vence, L. M., Perler, F. B., Benner, J., Kucera, R. B., Hirvonen, C. A., Pelletier, J. J., Paulus, H., and Xu, M. Q. (1997). Single-column purification of free recombinant proteins using a self-cleavable affinity tag derived from a protein splicing element. Gene 192:271-281.PubMed ID:9224900
  • Chong, S., Williams, K.S., Wotkowicz, C. and Xu, M.Q. (1998). Modulation of protein splicing of the saccharomyces cerevisiae vacuolar membrane ATPase intein. J. Biol. Chem. 273:10567-77.PubMed ID:9553117
  • Chong, S., Montello, G.E., Zhang, A., Cantor, E.J., Liao, W., Xu, M.-Q. and Benner, J. (Nov. 1998). Utilizing the C-terminal cleavage activity of a protein splicing element to purify recombinant proteins in a single chromatographic step. Nucl. Acids Res. 26(22):5109-5115.PubMed ID:9801307
  • Chong, S. and Perler, F.B. (Mar 2003). Intein-mediated Protein Purification, IN Methods and Tools in Biosciences and Medicine (M. Blot, Ed.) pages 173-193.
  • Christ, C., and Nelson, M. (1984). DNA modification methylases: New uses in the manipulation of DNA. BioTechniques 2:218-221.
  • Colina, K. F., Perler, F. B., Matsumura, I., Meda, M., and Nutman, T. B. (1990). The identification of an Onchocerca-specific recombinant antigen containing a T cell epitope. J Immunol. 145:1551-1556.PubMed ID:1696601
  • Conway, G., Margoliath, A., Wong-Madden, S., Roberts, R. J., and Gilbert, W. (1997). Jak1 kinase is required for cell migrations and anterior specification in zebrafish embryos. Proc. Natl. Acad. Sci. USA 94:3082-3087.PubMed ID:9096349
  • Cook, S. N., Jack, W. E., Xiong, X., Danley, L. E., Ellman, J. A., Shultz, P. G., and Noren, C. J. (1995). Photochemically initiated protein splicing. Angew. Chem. Int. Ed. Engl. 34:1629-1630.
  • Creasey, A., D'Angio, L., Dunne, T.S., Kissinger, C., O'Keefe, T., Perry-O'Keefe, H., Moran, L.S., Roskey, M., Schildkraut, I. and Sears, L.E. (1991). Application of a novel chemiluminescence-based DNA detection method to single-vector and multiplex DNA sequencing. Biotechniques 11:102-109.PubMed ID:1954008
  • Crossgrove, K., Laudet, V. and Maina, C.V. (2002). Dirofilaria immitis encodes Di-nhr-7, a putative orthologue of the Drosophila ecdysone-regulated E78 gene. Molecular & Biochemical Parasitology 119:169-177.
  • Cui, T., Liao, P.H., Guan, C. and Guo, H.C. (1999). Purification and crystallization of precursors and autoprocessed enzymes of Flavobacterium glycosylasparaginase: an N-terminal nucleophile hydrolase. Acta Cryst. D Biol. Cryst. 55(11):1961-1964.PubMed ID:10531509
  • Dila, D., and Raleigh, E. A. (1988). Genetic dissection of the methylcytosine-specific restriction system mcrB of Escherichia coli K-12. Gene 74:23-24.PubMed ID:2854808
  • Dila, D., Sutherland, E., Moran, L., Slatko, B., and Raleigh, E. A. (1990). Genetic and sequence organization of the mcrBC locus of Escherichia coli K-12. J. Bacteriol. 172:4888-4900.PubMed ID:2203735
  • Ding, Y., Xu, M.-Q., Ghosh, I., Chen, X., Ferrandon, S., Lesage, G., Rao, Z. (2003). Crystal structure of a mini-intein reveals a conserved catalytic module involved in side chain cyclization of asparagine during protein splicing. J. Biol. Chem. 278(40):39133-39142.PubMed ID:12878593
  • Dissanayake, S., Perler, F. B., Xu, M., Southworth, M. W., Yee, C. K., Wang, S., Dreyer, G., Watawana, L., Kurniawan, L., Fuhrman, J. A., and Piessens, W. F. (1995). Differential recognition of microfilarial chitinase, a transmission-blocking vaccine candidate antigen, by sera from patients with Brigian and Bancroftian filariasis. Am. J. Trop. Med. Hyg. 53:289-294.PubMed ID:7573715
  • Dorner, L. F., and Schildkraut, I. (1994). Direct selection of binding proficient/catalytic deficient variants of BamHI endonuclease. Nucl. Acids. Res. 22:1068-1074.PubMed ID:7908739
  • Dorner, L. F., Bitinaite, J., Whitaker, R. D.and Schildkraut, I. (1999). Genetic Analysis of the Base-specific Contacts of BamHI Restriction Endonuclease. J. Mol. Biol. 285:1515-1523.PubMed ID:9917393
  • Eberl, D. F., Lorenz, L. J., Melnick, M. B., Sood, V., Lasko, P., and Perrimon, N. (1997). A New Enhancer of Position-Effect Variegation in Drosophila melanogaster Encodes a Putative RNA Helicase That Binds Chromosomes and Is Regulated by the Cell Cycle. Genetics Society of America 146:951-963.PubMed ID:9215899
  • Edgar, M. A., Pasinelli, P., DeWit, M., Anton, B., Dokas, L. A., Pastorino, L., DiLuca, M., Cattabeni, F., Gispen, W. H. and DeGraan, P. N. (1997). Phosphorylation Of The Casein Kinase II Domain Of B-50 (GAP-43) In Rat Cortical Growth Cones. J. Neurochem. (US) 69(5):2206-2215.PubMed ID:9349568
  • Edwards, M. K., Busto, P., James, E. R., Carlow, C. K. S., and Philipp, M. (1990). Antigenic and dynamic properties of the surface of Onchocerca microfilariae. Trop. Med. Parasitol. 41:174-180.PubMed ID:2200104
  • Ehrlich, M., Wilson, G. G., Kenneth, C. K., and Gehrke, C. W. (1987). N4-Methylcytosine as a minor base in bacterial DNA. J. Bacteriol. 169:939-943.PubMed ID:3029036
  • Ellis, P.J., Carlow, C.K.S., Ma, D. and Kuhn, P. (1998). Crystal Structure of the Complex of Brugia Malayi Cyclophilin and Cyclosporin A. Protein Sci. 7:1310-1316.
  • Ellis, P.J., Carlow, C.K.S., Ma, D. and Kuhn, P. (2000). Crystal Structure of the Complex of Brugia Malayi Cyclophilin and Cyclosporin A. Biochemistry 39(3):592-598.PubMed ID:10642184
  • Engler, L.E., Sapienza, P., Dorner, L.F., Kucera, R., Schildkraut, I. and Jen-Jacobson, L. (2001). The Energetics of the Interaction of BamHI Endonuclease with its Recognition Site GGATCC. J. Mol. Biol. 307:619-636.PubMed ID:11254386
  • Evans, P. D., Cook, S. N., Riggs, P. D., and Noren, C. J. (1995). LITMUS: Multipurpose cloning vectors with a novel system for bidirectional in vitro transcription. Biotechniques 19:130-135.PubMed ID:7669286
  • Evans, T.C., Benner, J. and Xu, M-Q (1998). Semisynthesis of cytotoxic proteins using a modified protein splicing element. Protein Sci. 7(11):2256-2264.PubMed ID:9827992
  • Evans, T.C., Benner, J. and Xu, M-Q (1999). The in Vitro Ligation of Bacterially Expressed Proteins Using an Intein from Methanobacterium thermoautotrophicum. J. Biol. Chem. 274(7):3923-3926.PubMed ID:9933578
  • Evans, T.C., Benner, J. and Xu, M-Q (1999A). The Cyclization and Polymerization of Bacterially Expressed Proteins Using Modified Self-splicing Inteins. J. Biol. Chem. 274(26):18359-18363.PubMed ID:10373440
  • Evans, T.C. and Xu, M-Q (1999B). Intein-Mediated Protein Ligation: Harnessing Nature's Escape Artists. Biopolymers 51:333-342.PubMed ID:10685044
  • Evans, T.C., Martin, D., Kolly, R., Panne, D., Sun, L., Ghosh, I., Chen, L., Benner, J., Liu, X-Q and Xu, M-Q (2000). Protein trans-Splicing and Cyclization by a Naturally Split Intein from the dnaE Gene of Synechocystis Species PCC6803. J. Biol. Chem. 275(13):9091-9094.PubMed ID:10734038
  • Evans, T.C., Jr. and Xu, M-Q (2002). Mechanistic and kinetic considerations of protein splicing. Chem. Rev. 102(12):4869-4884.PubMed ID:12475209
  • Ferrandon, S., Sterzenbach, T., Mersha, F.B. and Xu, M-Q (2003). A single surface tryptophan in the chitin-binding domain from Bacillus circulans chitinase A1 plays a pivotal role in binding chitin and can be modified to create an elutable affinity tag. Biochim. Biophys. Acta. 1621:31-40.PubMed ID:12667608
  • Ferrer, M., Godbout, K., Sullivan, B., Austen, D., Sanderson, C., Kelley, K., Osburne, M., Harrison, S. and van Schravendijk, M. R. (1997). Construction and characterization of a radio-iodinatable mutant of recombinant human CD4. J. Immunol. Methods 210:215-225. PubMed ID:9520304
  • The Filarial Genome Project (1999). Deep within the Filarial Genome: Progress of the Filarial Genome Project. Parasitology Today 15(6):219-224.
  • Fischer, P., Bonow, I., Buttner, D.W., Kamal, I.H. and Liebau, E. (2003). An aspartate aminotransferase of Wolbachia endobacteria from Onchocerca volvulus is recognized by IgG1 antibodies from residents of endemic areas. Parasitology Research 90:38-47.PubMed ID:12743802
  • Fomenkov, A., Xiao, J. P., Dila, D., Raleigh, E., and Xu, S. Y. (1994). The 'endo-blue method' for direct cloning of restriction endonuclease genes in E. coli. Nucl. Acids Res. 22:2399-2403.PubMed ID:8036170
  • Fomenkov, A., Xiao, J. P., and Xu, S. Y. (1995). Nucleotide sequence of a small plasmid isolated from Acetobacter pasteurianus. Gene 158:143-144.PubMed ID:7789800
  • Fomenkov, A., and Xu, S.Y. (1995B). Isolation of temperature-sensitive mutants of the BamHI restriction endonuclease. Gene 157:303-310.PubMed ID:7607513
  • Fomenkov, A., and Xu, S. Y. (1995C). Cloning of a gene from Thermus filiformis and characterization of the thermostable nuclease. Gene 163:109-113.PubMed ID:7557458
  • Foster, J.M., Christodoulou, Z., Cowan, G.M. and Newbold, C.I. (1999). Thermal Asymmetric Interlaced PCR Amplification of YAC Insert End Fragments for Chromosome Walking in Plasmodium falciparum and Other A/T-Rich Genomes. BioTechniques 27(2):240-248.PubMed ID:10457822
  • Foster, J.M., Kamal, I.H., Daub, J., Swan, M.C., Ingram, J.R., Ganatra, M., Ware, J., Guiliano, D., Aboobaker, A., Moran, L., Blaxter, M. and Slatko, B.E. (2001). Hybridization of High-Denisty Filter Arrays of a Brugia malayi BAC Library with Biotinylated Oligonucleotides and PCR Products. BioTechniques 30(6):1216-1222.PubMed ID:11414208
  • Foster, J.M. and Johnston, D.A. (2002). Helminth genomics: from gene discovery to genome sequencing. Trends Parasitol 18(6):241-242.
  • Fuhrman, J. A., Lane, W. S., Smith, R. F., Piessens, W. F., and Perler, F. B. (1992). Transmission-blocking antibodies recognize microfilarial chitinase in brugian lymphatic filariasis. Proc Natl Acad Sci USA 89:1548-1552.PubMed ID:1542646
  • Galburt, E.A., Pelletier, J., Wilson, G. and Stoddard, B.L. (2002). Structure of a tRNA Repair Enzyme and Molecular Biology Workhorse: T4 Polynucleotide Kinase. Structure 10(9):1249-1260.
  • Gardner, A.F. and Jack, W.E. (1999). Determinants of nucleotide sugar recognition in an archaeon DNA polymerase. Nuc. Acids Res. 27(12):2545-2553.PubMed ID:10352184
  • Gardner, A.F. and Jack, W.E. (2002). Acyclic and dideoxy teminator preferences denote divergent sugar recognition by archaeon and Taq DNA polymerases. Nuc. Acids Res. 30(2):605-613.PubMed ID:11788725
  • Garraud, O., Nkenfou, C., Bradley, J. E., Perler, F. B., and Nutman, T. B. (1995). Identification of recombinant filarial proteins capable of inducing polyclonal and antigen-specific IgE and IgG4 antibodies. J. Immunol. 155:1316-1325.PubMed ID:7543519
  • Garraud, O., Perler, F. B., Bradley, J. E., and Nutman, T. B. (1997). Induction of Parasite Antigen-Specific Antibody Responses in Unsensitized Human B Cells is Dependent on the Presence of Cytokines After T Cell Priming. J. Immunol. 159:4793-4798.PubMed ID:9366403
  • Gbakima, A. A., Nutman, T. B., Bradley, J. E., McReynolds, L. A., Winget, M. D., Hong, Y., and Scott, A. L. (1996). Immunoglobulin G Subclass Responses of Children during Infection with Onchocerca volvulus. Clinical and Diagnostic Laboratory Immunology 3:98-104.PubMed ID:8770512
  • Ghosh, I., Sun, L. and Xu, M.Q. (2001). Zinc Inhibition of Protein trans-Splicing and Identification of Regions Essential for Splicing and Association of a Split Intein. J. Biol. Chem. 276(26):24051-24058.PubMed ID:11331276
  • Gingeras, T. R., Greenough, L., Schildkraut, I., and Roberts, R. J. (1981). Two new restriction endonucleases from Proteus vulgaris. Nucl. Acids Res. 9:4525-4536.PubMed ID:6272209
  • Gingras, A-C., Gygi, S.P., Raught, B., Polakiewicz, R.D., Abraham, R.T., Hoekstra, M.F., Aebersold, R. and Sonenberg, N. (1999). Regulation of 4E-BP1 phosphorylation: a novel two-step mechanism. Genes & Devel. 13:1422-1437.PubMed ID:10364159
  • Giriat, I., Muir, T.W. and Perler, F.B. (2001). Protein splicing and its aplications. Genet. Eng. (NY) 23:171-199.PubMed ID:11570103
  • Grandea, A. G. I., Le, T. K. T., Asikin, N., Davis, T. B., Philipp, M., Cohen, C., and McReynolds, L. A. (1989). A l gt11 cDNA recombinant that encodes Dirofilaria immitis paramyosin. Mol. Biochem. Parasitol. 35:31-41.PubMed ID:2527335
  • Grogan, D.W. (2003). Cytosine methylation by the SuaI restriction-modification system: implications for genetic fidelity in a hyperthermophilic archaeon. J. Bacteriol. 185(15):4657-4661.PubMed ID:12867480
  • Guan, C., Wanner, B., and Inouye, H. (1983). Analysis of Regulation of phoB Expression Using a phoB-cat Fusion. J. Bacteriol. 156:710-717.PubMed ID:6313614
  • Guan, C. D., Li, P., Riggs, P. D., and Inouye, H. (1988). Vectors that facilitate the expression and purification of foreign peptides in Escherichia coli by fusion to maltose-binding protein. Gene 67:21-30.PubMed ID:2843437
  • Guan, C., Cui, T., Rao, V., Liao, W., Benner, J., Lin, C. L., and Comb, D. (1996). Activation of glycosylasparaginase. Formation of Active N-Terminal Threonine by Intramolecular Autoproteolysis. J. Biol. Chem. 271:1732-1737.PubMed ID:8576176
  • Guan, C., Liu, Y., Shao, Y., Cui, T., Liao, W., Ewel, A., Whitaker, R. and Paulus, H. (1998). Characterization and functional analysis of the cis-autoproteolysis active center of glycosylasparaginase. J. Biol. Chem. 273:9695-702.PubMed ID:9545304
  • Guiliano, D., Ganatra, M., Ware, J., Parrot, J., Daub, J., Moran, L., Brennecke, H., Foster, J.M., Supali, T., Blaxter, M., Scott, A.L., Williams, S.A. and Slatko, B.E. (1999). Chemiluminescent Detection of Sequential DNA Hybridizations to High-Density, Filter-Arrayed cDNA Libraries: A Subtraction Method for Novel Gene Discovery. BioTechniques 27(1):146-152PubMed ID:10407677
  • Guo, H.-C., Xu, Q., Buckley, D. and Guan, C. (1998). Crystal Structures of Flavobacterium Glycosylasparaginase. J. Biol. Chem., 273:20205-20212.PubMed ID:9685368
  • Guthrie, E. P., Quinton-Jager, T., Moran, L. S., Slatko, B. E., Kucera, R. B., Benner, J. S., Wilson, G. G., and Brooks, J. E. (1996). Cloning, expression and sequence analysis of the SphI restriction-modification system. Gene 180:107-112.PubMed ID:8973353
  • Hall, M.F., Noren, C., Perler, F. and Schildkraut, I. (Oct 2002). Creation of an Artificial Bifunctional Intein by Grafting a Homing Endonuclease into a Mini-intein. J. Mol. Biol. 323(2):173-179.PubMed ID:12381313
  • Herman, J., Nelkin, B., Mabry, M., Wilson, G., and Baylin, S. (1989). Introduction of prokaryotic HhaI DNA methyltransferase alters the phenotype of 3T3 cells. Proc. Am. Assoc. Cancer Res. 30:428.
  • Higgins, L.S., Besnier, C. and Kong H. (2001). The nicking endonuclease N.BstNBI is closely related to Type IIs restriction endonucleases MlyI and PleI. Nucl. Acids Res. 20:2492-2501.PubMed ID:11410656
  • Hingorani, K. and Bitinaite, J. (2003). Kinetic analysis of the coordinated interaction of SgrAI restriction endonuclease with different DNA targets. J. Biol. Chem. 278:40392-40399.PubMed ID:12851384
  • Hirsch, J. A., Wah, D. A., Dorner, L. F., Schildkraut, I., Aggarwal, A. K. (1997). Crystallization and Preliminary X-ray Analysis of Restriction Endonuclease FokI Bound to DNA. FEBS Lett. 403(2):136-138.PubMed ID:9042953
  • Hlavaty, J.J., Benner, J.S., Hornstra, L.J. and Schildkraut, I. (2000). Identification of the Metal-Binding Sites of Restriction Endonucleases by Fe2+-Mediated Oxidative Cleavage. Biochemistry 39(11):3097-3105.PubMed ID:10715131
  • Hodges, R. A., Perler, F. B., Noren, C. J., and Jack, W. E. (1992). Protein splicing removes intervening sequences in an archaea DNA polymerase. Nucl. Acids Res. 20:6153-6157.PubMed ID:1475179
  • Hong, X. Q., Mejia, J. S., Nkenfou, C., Perler, F. B., and Carlow, C. K. (1995). A Promising Recombinant Antigen for the Early Detection of Heartworm Infection. Proceeding of the Heartworm Symposium, 141-146.
  • Hong, X. Q., Mejia, J. S., Kumar, S., Perler, F. B., and Carlow, C. K. S. (1996). Cloning and Expression of DiT33 from Dirofilaria-Immitis - a Specific and Early Marker of Heartworm Infection. Parasitology 112:331-338.PubMed ID:8728997
  • Hong, X., Ma, D. and Carlow, C. K. S. (1998). Cloning, expression and characterization of a new filarial cyclophilin. Mol Biochem Parasitol. 91:353-8.PubMed ID:9566526
  • Hong, X., Ma, D., Page, A.P., Kumar, S. and Carlow, C. K. S. (1998). A highly conserved large molecular weight cyclophilin of filarial parasites. Exp Parasitol. 88:246-51.PubMed ID:9562430
  • Horton, J.R., Nastri, H.G., Riggs, P.D. and Cheng, X. (1998). Asp34 of PvuII Endonuclease is Directly Involved in DNA Minor Groove Recognition and Indirectly Involved in Catalysis. J. Mol. Biol. 284:1491-1504.PubMed ID:9878366
  • Horton, N.C, Dorner, L.F., Schildkraut, I. and Perona J.J. (1999). Crystallization and preliminary diffractin analysis of the HincII restriction endonuclease-DNA complex. Acta Cryst. Biol. Cryst. 55(11):1943-1945.PubMed ID:10531503
  • Hough, D. M., Awobuluyi, M. E., McReynolds, L. A., Carlow, C. K. S., and Maina, C. V. (1992). Using Molecular Biological Techniques to Identify and Study Gene Products Involved in Dirofilarial Immunoprophylaxis. American Heartworm Society, 139-142.
  • Howard, K. A., Card, C., Benner, J. S., Callahan, H. L., Maunus, R., Silber, K., Wilson, G., and Brooks, J. E. (1986). Cloning the DdeI restriction-modification system using a two-step method. Nucl. Acids Res. 14:7939-7951.PubMed ID:3022241
  • Hsieh, P.-C., Xiao, J.-P., O'Loane, D. and Xu, S.-Y. (2000). Cloning, Expression and Purification of a Thermostable Nonhomodimeric Restriction Enzyme, BslI. J. Bacteriol. 182(4):949-955.PubMed ID:10648519
  • Ives, C. L., Nathan, P. D., and Brooks, J. E. (1992). Regulation of the BamHI restriction-modification system by a small intergenic open reading frame, bamHIC, in both Escherichia coli and Bacillus subtilis. J. Bacteriol. 174:7194-7201.PubMed ID:1429443
  • Ives, C. L., Sohail, A., and Brooks, J. E. (1995). The regulatory C proteins from different restriction-modification systems can cross-complement. J. Bacteriol. 177:6313-6315.PubMed ID:7592403
  • Jack, W. E., Greenough, L., Dorner, L. F., Xu, S. Y., Strzelecka, T., Aggarwal, A. K., and Schildkraut, I. (1991). Overexpression, purification and crystallization of BamHI endonuclease. Nucl. Acids Res. 19:1825-1829.PubMed ID:2030964
  • James, E. R., McLean, D. C. J., and Perler, F. B. (1994). Molecular Cloning of an Onchocerca volvulus Extracellular Cu-Zn Superoxide Dismutase. Infect. Immun. 62:713-716.PubMed ID:8300230
  • Jin, J., Poole, C.B., Slatko, B.E. and McReynolds, L.A. (1999). Alternative splicing creates sex-specific transcripts and truncated forms of the furin protease in the parasite Dirofilaria immitis. Gene 237(1):161-175.PubMed ID:10524247
  • Johnston, D.A., Blaxter, M.L., Degrave, W.M., Foster, J., Ivens, A.C. and Melville, S.E. (1999). Genomics and the biology of parasites. BioEssays 21:131-147.
  • Joshua, G. W., Perler, F. B., and Wang, C. C. (1995). Orphon spliced-leader sequences form part of a repetitive element in Angiostrongylus cantonensis. Nucl. Acids Res. 23:1030-1035.PubMed ID:7731790
  • Kelleher, J. E., and Raleigh, E. A. (1991). A Novel Activity in Escherichia coli K-12 That Directs Restriction of DNA Modified at CG Dinucleotides. J. Bacteriol. 173:5220-5223.PubMed ID:1830580
  • Kelleher, J. E., and Raleigh, E. A. (1994). Response to UV Damage by Four Escherichia coli K-12 Restriction Systems. J. Bacteriol. 176:5888-5896.PubMed ID:7928948
  • Kelleher, J. E., and Raleigh, E. A. (1995). On the regulation and diversity of restriction in Esherichia coli. Gene 157:229-230.PubMed ID:7607495
  • Kelley, K.C., Huestis, K.J., Austen, D.A., Sanderson, C.T., Donoghue, M.A., Stickel, S. ., Kawasaki, E.S., and Osburne, M.S. (1995). Regulation of sCD4-183 gene expression from phage-T7-based vectors in Escherichia coli. Gene 156:33-36.PubMed ID:7737513
  • Kelley, K., Verma, I. and Pierce, G.F. (2002). Gene therapy: reality or myth for the global bleeding disorders community?. Haemophilia 8(3):261-267.PubMed ID:12010421
  • Kim, G.D., Ni, J., Kelesoglu, N., Roberts, R.J. and Pradhan, S. (2002). Co-operation and communication between the human maintenance and de novo DNA (cytosine-5) methyltransferases. EMBO J. 21(15):4183-4195.PubMed ID:12145218
  • Klimasauskas, S., Kumar, S., Roberts, R. J., and Cheng, X. (1994). Hhal Methyltransferase Flips its Target Base Out of the DNA Helix. Cell 76:357-369.PubMed ID:8293469
  • Klimasauskas, S. and Roberts, R. J. (1995). M.Hhal binds tightly to substrates containing mismatches at the target base. Nucl. Acids Res. 23:1388-1395.PubMed ID:7753630
  • Klimasauskas, S., and Roberts, R. J. (1995). Disruption of the target G-C base-pair by the HhaI methyltransferase. Gene 157:163-164.PubMed ID:7607483
  • Kong, H and Chen, Z. (1987). Isolation and Identification of restriction endonuclease BstFI. Nucl. Acids Res. 15(17):7205.PubMed ID:2821503
  • Kong, H., Morgan, R. D., and Chen, Z. (1990). A new type II restriction endonuclease, BsmAI, from Bacillus stearothermophilus. Nucl. Acids Res. 18:686.PubMed ID:2308865
  • Kong, H., Morgan, R. D., and Chen, Z. (1990). Identification of a new type II restriction endonuclease BsaAI. Nucl. Acids Res. 18:2832.PubMed ID:2339077
  • Kong, H., Morgan, R. D., Maunus, R. E., and Schildkraut, I. (1993). A unique restriction endonuclease, BcgI, from Bacillus coagulans. Nucl. Acids Res. 21:987-991.PubMed ID:8451198
  • Kong, H., Kucera, R. B., and Jack, W. E. (1993). Characterization of DNA Polymerase from the Hyperthermophile Archaea Thermococcus litoralis. J. Biol. Chem. 268:1965-1975.PubMed ID:8420970
  • Kong, H., Roemer, S. E., Waite-Rees, P. A., Benner, J. S., Wilson, G. G., and Nwankwo, D. O. (1994). Characterization of BcgI, a new kind of restriction-modification system. J. Biol. Chem. 269:683-690.PubMed ID:8276869
  • Kong, H., and Smith, C. L. (1997). Substrate DNA and cofactor regulate the activities of a multi-functional restriction-modification enzyme, Bcgl. Nucl. Acids Res. 25:3687-3692.PubMed ID:9278491
  • Kong, H., and Smith, C. L. (1998a). Does Bcg1, a Unique Restriction Endonuclease, Require Two Recognition Sites for Cleavage? J Biol. Chem 379:605-609.
  • Kong, H (1998b). Analyzing the Functional Organization of a Novel Restriction Modification System, the BcgI System. J. Mol. Biol. 279:823-832.PubMed ID:9642063
  • Kong, H., Lin, L.F., Porter, N., Stickel, S. Byrd, D., Posfai, J. and Roberts R.J. (2000). Functional analysis of putative restriction-modification system genes in the Helicobacter pylori J99 genome. Nucl. Acids Res. 28(17):3216-3223.PubMed ID:10954588
  • Kozlova, T., Pokholkova, G.V., Tzertzinis, G., Sutherland, J.D., Zhimulev, I.F. and Kafatos, F.C. (1998). Drosophila Hormone Receptor 38 Functions in Metamorphosis: A Role in Adult Cuticle Formation. Genetics 149:1465-1475.PubMed ID:9649534
  • Kuhn, P., Guan, C., Cui, T., Tarentino, A. L., Plummer, T. H. J., and Van Roey, P. (1995). Active site and oligosaccharide recognition residues of peptide-N4-(N-acetyl-beta-D-glucosaminyl)asparagine amidase F. J. Biol. Chem. 270:29493-29497.PubMed ID:7493989
  • Kulakauskas, S., Barsomian, J. M., Lubys, A., Roberts, R. J., and Wilson, G. G. (1994). Organization and sequence of the HpaII restriction-modification system and adjacent genes. Gene 142:9-15.PubMed ID:7514149
  • Kumar, S., Cheng, X., Klimasauskas, S., Sha, M., Posfai, J., Roberts, R. J., and Wilson, G. G. (1994). The DNA (cytosine-5) methyltransferases. Nucl. Acids Res. 22:1-10.PubMed ID:8127644
  • Kumar, S., Horton, J. R., Jones, G. D., Walker, R. T., Roberts, R. J., and Cheng, X. (1997). DNA containing 4'-thio-2' deoxycytidine inhibits methylation by HhaI methyltransferase. Nucl. Acids Res. 25:2773-2783.PubMed ID:9207024
  • Labahn, J., Granzin, J., Schluckebier, G., Robinson, D. P., Jack, W. E., Schildkraut, I., and Saenger, W. (1994). Three-dimensional structure of the adenine-specific DNA methyltransferase M.Taq I in complex with the cofactor S-adenosylmethionine. Proc. Natl. Acad. Sci. USA 91:10957-10961.PubMed ID:7971991
  • Landry, D., Looney, M. C., Feehery, G. R., Slatko, B. E., Jack, W. E., Schildkraut, I., and Wilson, G. G. (1989). M.FokI methylates adenine in both strands of its asymmetric recognition sequence. Gene 77:1-10.PubMed ID:2744483
  • Landry, D., Barsomian, J. M., Feehery, G. R., and Wilson, G. G. (1992). Characterization of Type II DNA-Methyltransferases. Methods Enzymol. 216:244-259.PubMed ID:1479902
  • Lee, K-F, Shaw, P-C, Picone, S.J., Wilson, G.G. and Lunnen, K.D. (1998). Sequence Comparison of the EcoHK31I and EaeI Restriction-Modification Systems Suggests an Intergenic Transfer of Genetic Material. Biol. Chem. 379:437-441.PubMed ID:9628335
  • Limberger, R. J., and McReynolds, L. A. (1990). Filarial paramyosin: cDNA sequences from Dirofilaria immitis and Onchocerca volvulus. Mol. Biochem. Parasitol. 38:271-280.PubMed ID:2325708
  • Lin, L.F., Posfai, J., Roberts, R.J. and Kong, H. (2001). Comparative genomics of the restriction-modification systems in Helicobacter pylori. Proc. Natl. Acad. Sci. USA 98:2740-2745.
  • Liu, Y., Guan, C. and Aronson, N. N., Jr. (1998). Site-directed Mutagenesis of Essential Residues Involved in the Mechanism of Bacterial Glycosylasparaginase. J. Biol. Chem. 273(16):9688-9694.PubMed ID:9545303
  • Looney, M. C., Moran, L. S., Jack, W. E., Feehery, G. R., Benner, J. S., Slatko, B. E., and Wilson, G. G. (1989). Nucleotide sequence of the FokI restriction-modification system: separate strand-specificity domains in the methyltransferase. Gene 80:193-208.PubMed ID:2684765
  • Low, K. G., Dorner, L. F., Fernando, D. B., Grossman, J., Jeang, K. T., and Comb, M. J. (1997). Human T-Cell Lukemia Virus Type 1 Tax Releases Cell Cycle Arrest Induced by p16INK4a. J. Virol. 71:1956-1962.PubMed ID:9032327
  • Lukacs, C.M., Kucera, R., Schildkraut, I. and Aggarwal, A.K. (2000).Understanding the immutability of restriction enzymes: crystal structure of BglII and its DNA substrate at 1.5 angstrom resolution. Nature Struct. Biol. 7(2):134-140.PubMed ID:10655616
  • Lunnen, K. D., Barsomian, J. M., Camp, R. R., Card, C. O., Chen, S. Z., Croft, R., Looney, M. C., Meda, M. M., Moran, L. S., Nwankwo, D. O., Slatko, B. E., Van Cott, E. M., and Wilson, G. G. (1988). Cloning Type II restriction and modification genes. Gene 74:25-32.PubMed ID:3074013
  • Lunnen, K. D., Morgan, R. D., Timan, C. J., Krzycki, J. A., Reeve, J. N., and Wilson, G. G. (1989). Characterization and cloning of MwoI (GCN7GC), a new type-II restriction-modification system from Methanobacterium wolfei. Gene 77:11-19.PubMed ID:2663652
  • Ma, D., Hong, X. Q., Raghavan, N., Scott, A. L., McCarthy, J. A., Nutman, T. B., Williams, S. A., and Carlow, C. K. S. (1996). A Cyclosporine A-Sensitive Small Molecular-Weight Cyclophilin Of Filarial Parasites. Molec. Biochem. Parasitol. 79:235-241.PubMed ID:8855561
  • Ma, D. and Carlow, C. K. S. (1998). Active site mutants of a cyclosporin A-insensitive cyclophilin from Brugia malayi: effect on catalysis and drug binding. Molec. Biochem. Parasitol., 92:361-365.
  • Ma, D. and Carlow, C.K.S. (1999). Molecular characterization of FKBP13 from filarial parasites. Molec. Biochem. Parasitol. 99:263-267.PubMed ID:10340490
  • Ma, D., Nelson, L.S., LeCoz, K., Poole, C. and Carlow, C.K.S. (2002). A novel cyclophilin from parasitic and free-living nematodes with a unique substrate-and drug-binding domain. J. Biol. Chem. 277(17):14925-14932.PubMed ID:11847225
  • Maina, C. V., Grandea, A. G. I., Le, T. K. T., Nur, A., Williams, S. A., and McReynolds, L. A. (1987). Dirofilaria immitis: Genomic Complexity and Characterication of a Structural Gene. Molecular Paradigms for Eradicating Helminthic Parasites; Alan R. Liss, Inc., 193-204.
  • Maina, C. V., Riggs, P. D., Grandea, A. G. I., Slatko, B. E., Moran, L. S., Tagliamonte, J. A., McReynolds, L. A., and Guan, C. D. (1988). An Escherichia coli vector to express and purify foreign proteins by fusion to and separation from maltose-binding protein. Gene 74:365-373.PubMed ID:3073105
  • Margot, J.B., Aguirre-Arteta, A.M., DiGiacco, B.V., Pradhan, S., Roberts, R.J., Cardoso, M.C. and Leonhardt, H. (2000). Structure and function of the mouse DNA methyltransferase Gene, DNMT1 shows a tripartite structure. J. Mol. Biol. 297:293-300.PubMed ID:10715201
  • Martin, D.D., Xu, M-Q and Evans, T.C. Jr. (2001). Characterization of a naturally occurring trans-splicing intein from Synechocystis sp. PCC6803. Biochemistry 40(5):1393-1402.PubMed ID:11170467
  • Mathys, S., Evans, T.C., Chute, I.C., Wu, H., Chong, S., Benner, J., Liu, X.Q. and Xu, M.Q. (1999). Characterization of a self-splicing mini-intein and its conversion into autocatalytic N- and C-terminal cleavage elements: facile production of protein building blocks for protein ligation. Gene 231:1-13.PubMed ID:10231563
  • McClelland, M., and Nelson, M. (1985). The effect of site specific methylation on restriction endonuclease digestion. Nucl. Acids Res. 13:r201-r207.PubMed ID:2987886
  • McClelland, M., Nelson, M., and Cantor, C. R. (1985). Purification of MboII methylase (GAAGmA) from Moraxella bovis: site specific cleavage of DNA at nine and ten base pair sequences. Nucl. Acids Res. 13:7171-7182.PubMed ID:2997742
  • McClelland, M., Jones, R., Patel, Y., and Nelson, M. (1987). Restriction endonucleases for pulsed field mapping of bacterial genomes. Nucl. Acids Res. 15:5985-6005.PubMed ID:2819819
  • McClelland, M., and Nelson, M. (1987). Enhancement of the apparent cleavage specificities of restriction endonucleases: applications to megabase mapping of chromosomes., Volume 5, J. G. Chirikjian, ed. (Holland: Elsevier North ).
  • McIlwrath, A.J. (2001). Qualitative detection of apoptotic cells assessed by DNA fragmentation. Methods Mol. Biol. 174:189-195.PubMed ID:11357643
  • McReynolds, L. A., DeSimone, S. M., and Williams, S. A. (1986). Cloning and comparison of repeated DNA sequences from the human filarial parasite Brugia malayi and the animal parasite Brugia pahangi. Proc. Natl. Acad. Sci. USA 83:797-801.PubMed ID:3003750
  • McReynolds, L. A., Poole, C. B., Williams, S. A., Partono F. Diagnosis of Filariasis with DNA Probes. Rapid Methods and Automation in Microbiology and Immunology pgs 402-409. A. Vaheri, R.C. Tilton and A. Balows eds. (Springer-Verlag).
  • McReynolds, L. A., Poole, C. B., and Williams, S. A. (1991). Filarial DNA probes in Jakarta. Parasitol. Today. 7:65 - 67.
  • McReynolds, L. A., Kennedy, M. W., and Selkirk, M. E. (1993). The Polyprotien Allergens of Nematodes. Parasitol. Today 9:403-406.
  • McReynolds, L. A., Poole, C., Hong, Y., Williams, S. A., Partono, F., and Bradley, J. (1993). Recent Advances in the Application of Molecular Biology in Filariasis. In Proceeding of the 34th SEAMEO TROPMED Regional Seminar: Southeast Asian Journal of Tropical Medicine and Public Health) pp. 55-63.PubMed ID:7973949
  • Mejia, J. S., and Carlow, C. K. S. (1994). An analysis of the humoral immune response of dogs following vaccination with irradiated infective larvae of Dirofilaria immitis. Parasite Immunol. 16:157-164.PubMed ID:8208588
  • Mejia, S.J., Knenfou, C., Southworth, M.W., Perler, F. B. and Carlow, C.K. (1994). Expression of an Onchocerca volvulus Ov33 homolog in Dirofilaria immitis: potential in immunodiagnosis of heartworm infection.. Parasite Immunol. 16:297-303PubMed ID:7970866
  • Mi, S., Alonso, D., and Roberts, R. J. (1995). Functional analysis of Gln-237 mutants of HhaI methyltransferase. Nucl. Acids Res. 23:620-627.PubMed ID:7899082
  • Milkman, R., Cryderman, D., McKane, M., McWeeny, K. and Raleigh E.A. (1998). Evolutionary evidence for recombination among bacteria in nature. E. coli. In Horizontal Gene Transfer (M.S. & Kado, C.), pages 226-240. Chapman and Hall, London
  • Milkman, R., Raleigh, E.A., McKane, M., Cryderman, D. and Pohlman, K. (1999). Molecular evolution of the Escherichia coli chromosome. V. Recombination patterns among strains of diverse origin. Genetics 153:539-554.PubMed ID:10511538
  • Mikol, V., Ma, D., Carlow, C. K. S. (1998) Crystal Structure of the Cyclophilin-like Domain from the Parasitic Nematode Brugia Malayi. Protein Sci. 7:1310-1316.PubMed ID:9655334
  • Moran, L. S., Maina, C. V., Poole, C. B., and Slatko, B. E. (1990). Nucleotide sequence of the phage l gt11 SacI-KpnI lacZ region. Gene 93:163-164.PubMed ID:2146187
  • Moreira, R. F., and Noren, C. J. (1995). Minimum duplex requirements for restriction enzyme cleavage near the termini of linear DNA fragments. Biotechniques 19:56-59.PubMed ID:7669297
  • Morgan, R. D., Dalton, M., and Stote, R. (1987). A unique type II restriction endonuclease from Acinetobacter lwoffi N. Nucl. Acids Res. 15:7201.PubMed ID:2821501
  • Morgan, R. D. (1988). MseI, a unique restriction endonuclease from Micrococcus species which recognizes 5'T^TAA 3'. Nucl. Acids Res. 16:3104.PubMed ID:2835752
  • Morgan, R. D., Camp, R. R., Wilson, G. G., and Xu, S. Y. (1996). Molecular cloning and expression of NlaIII restriction-modification system in E. coli. Gene 183:215-218.PubMed ID:8996109
  • Morgan, R., Xiao, J. P. and Xu, S. Y. (1998). Characterization of an Extremely Thermostable Restriction Enzyme, PspGI, from a Pyrococcus Strain and Cloning of the PspGI Restriction-Modification System in Escherichia coli. Appl. Environ. Microbiol. 64(10):3669-3673.PubMed ID:9758783
  • Morgan, R., Calvet, C., Demeter, M., Agra, R. and Kong, H. (2000). Characterization of the Specific DNA Nicking Activity of Restriction Endonuclease N.BstNBI. Biol. Chem. 381:1123-1125.PubMed ID:11154070
  • Narva, K. E., Van Etten, J. L., Slatko, B. E. and Benner, J. S. (1988). The Amino Acid Sequence of the Eukaryotic DNA [N6-adenine] Methyltransferase, M-CviBIII, Has Regions of Similarity With the Prokaryotic Isoschizomer M-TaqI and Other DNA [N6-adenine] Methyltransferases. Gene 74:253-259.PubMed ID:3248728
  • Nastri, H. G., Evans, P. D., Walker, I. H., and Riggs, P. D. (1997). Catalytic and DNA Binding Properties of PvuII Restriction Endonuclease Mutants. J. Biol. Chem. 272:25761-25767.PubMed ID:9325303
  • Nathan, P.D. and Brooks, J.E. (1988). Characterization of clones of the BamHI methyltransferase gene. Gene 74:35-36.PubMed ID:3248731
  • Nelson, M., Christ, C., and Schildkraut, I. (1984). Alteration of apparent restriction endonuclease recognition specificities by DNA methylases. Nucl. Acids Res. 12:5165-5173.PubMed ID:6087274
  • Nelson, M., and McClelland, M. (1987). The effect of site-specific methylation on restriction-modification enzymes. Nucl. Acids Res. 15:r219-r230.PubMed ID:3033612
  • Nelson, M., and Schildkraut, I. (1987). The use of DNA methylases to alter the apparent recognition specificities of restriction endonucleases. Methods Enzymol. 155:41-48.PubMed ID:2828873
  • Nelson, M., and McClelland, M. (1987). Purification and assay of Type II DNA methylases. Methods Enzymol. 155:32-41.PubMed ID:2828871
  • Newman, M., Strzelecka, T., Dorner, L. F., Schildkraut, I., and Aggarwal, A. K. (1994). Structure of restriction endonuclease BamHI and its relationship to EcoRI. Nature, 368:660-664.PubMed ID:8145855
  • Newman, M., Strzelecka, T., Dorner, L. F., Schildkraut, I., and Aggarwal, A. K. (1994). Structure of restriction endonuclease BamHI phased at 1.95 A resolution by MAD analysis. Structure 2:439-452.PubMed ID:8081758
  • Newman, M., Strzelecka, T., Dorner, L. F., Schildkraut, I., and Aggarwal, A. K. (1995). Structure of BamHI endonuclease bound to DNA: partial folding and unfolding on DNA binding. Science 269:656-663.PubMed ID:7624794
  • Newman, M., Lunnen, K., Wilson, G., Greci, J., Schildkraut, I., Phillips, S. E. (1998). Crystal Structure of Restriction Endonuclease BgII Bound to its Interrupted DNA Recognition Sequence. EMBO J. 17(18):5466-5476.PubMed ID:9736624
  • Ngu, J. L., Knenfou, C., Capuli, E., McMoli, T. E., Perler, F., Mbwagbor, J., Tumme, C., Nlatte, O. B., Donfack, J. and Asonganyi, T. (1998). Novel, sensitive and low-cost diagnostic tests for "river blindness" - detection of specific antigens in tears, urine and dermal fluid. Trop. Med. Inter. Health 3(5):339-348.PubMed ID:9623938
  • Nichols, N.M., Benner, J.S., Martin, D.D. and Evans, T.C. Jr. (2003). Zinc Ion Effects on Individual Ssp DnaE Intein Splicing Steps: Regulating Pathway Progression. Biochemistry 42:5301-5311.PubMed ID:12731871
  • Noren, C. J., and Moreira, R. F. (1996). Potent Inhibition Of T7 Rna-Polymerase With A Truncated T7 Promoter. Abstracts Of Papers Of The American Chemical Society 211, 156-Ched.
  • Noren, C.J., Wang, J. and Perler, F.B. (2000). Dissecting the Chemistry of Protein Splicing and its Applications. Angew. Chem. Int. Ed. 39:450-466.
  • Noren, K.A., Saltman, L.H. and Noren, C.J. (2000A). Construction and use of pIII-displayed peptide libraries" in Phage Display: A Laboratory Manual, pages 19.11-19.41 (Barbas, C.F., Burton, D.R., Scott, J.K. and Silverman, G.J. eds), CSHL Press.
  • Noren, K.A. and Noren, C.J. (2001). Construction of high-complexity combinatorial phage display peptide libraries. Methods 23(2):169-178.PubMed ID:11181036
  • Nwankwo, D., and Wilson, G. (1987). Cloning of two type II methylase genes that recognise asymmetric nucleotide sequences: FokI and HgaI. Mol. Gen. Genet. 209:570-574.PubMed ID:2828884
  • Nwankwo, D. O., and Wilson, G. G. (1988). Cloning and expression of the MspI restriction and modification genes. Gene 64:1-8.PubMed ID:2456254
  • Nwankwo, D. O., Moran, L. S., Slatko, B. E., Waite-Rees, P. A., Dorner, L. F., Benner, J. S., and Wilson, G. G. (1994). Cloning, analysis and expression of the HindIII R-M-encoding genes. Gene 150 75-80.PubMed ID:7959067
  • Nwankwo, D. O. (1995). Cloning of a pair of genes encoding isoschizomeric restriction endonucleases from Bacillus species: the BspEI and BspMII restriction and modification systems. Gene, 157:31-35.PubMed ID:7607514
  • Nwankwo, D. O., Lynch, J. J., Moran, L. S., Fomenkov, A., and Slatko, B. E. (1996). The XmnI Restriction-Modification System - Cloning, Expression, Sequence Organization And Similarity Between The R And M-Gene. Gene 173:121-127.PubMed ID:8964488
  • Nwankwo, D. O., Maunus, R. E., and Xu, S. Y. (1997). Cloning and expression of AatII restriction-modification system in Escherichia coli. Gene 185:105-109.PubMed ID:9034320
  • O'Gara, M., Klimasauskas, S., Roberts, R., and Cheng, X. D. (1996). Enzymatic C5-Cytosine Methylation Of DNA - Mechanistic Implications Of New Crystal-Structures For HhaI Methyltransferase-DNA-Adohcy Complexes. J. Mol. Biol. 261:634-645.PubMed ID:8800212
  • O'Gara, M., Roberts, R. J., and Cheng, X. (1996). A Structural Basis for the Preferential Binding of Hemimethylated DNA by HhaI DNA Methyltransferase. J. Mol. Biol. 263 597-606.PubMed ID:8918941
  • O'Gara, M., Horton, J.R., Roberts, R.J. and Cheng, X. (1998). Structures of HhaI methyltransferase complexed with substrates containing mismatches at the target base. Nature Struct. Biol. 5(10):872-877.PubMed ID:9783745
  • O'Gara, M., Zhang, X., Roberts, R.J. and Cheng, X. (1999). Structures of a Binary Complex of HhaI Methyltransferase with S-adenosyl-L-methionine Formed in the Presence of a Short Non-specific DNA Oligonucleotide. J. Mol. Biol. 287:201-209.PubMed ID:10080885
  • O'Loughlin, T.J., Xu, Q., Kucera, R.B., Dorner, L.F., Sweeney, S., Schildkraut, I. and Guo, H.-C. (2000). Crystallization and preliminary X-ray diffraction analysis of MspI restriction endonuclease in complex with its cognate DNA. Acta Cryst. D56:1652-1655.PubMed ID:11092936
  • Page, A. P., Kumar, S., and Carlow, C. K. S. (1995). Parasite Cyclophilins and Antiparasite Activity of Cyclosporin A. Parasitology Today 11:385-388.
  • Page, A. P., Landry, D., Wilson, G. G., and Carlow, C. K. S. (1995). Molecular Characterization of a Cyclosporin A-Insensitive Cyclophilin from the Parasitic Nematode Brugia malayi. Biochemistry 34:11545-11550.PubMed ID:7547885
  • Panne, D., Raleigh E. A., Bickle, T. A. (1998). McrBs, a modulator peptide for McrBC activity. EMBO J. 17:5477-5483.PubMed ID:9736625
  • Panne, D., Raleigh E. A. and Bickle, T. A. (1999). The McrBC Endonuclease Translocates DNA in a Reaction Dependent on GTP Hydrolysis. J. Mol. Biol. 290:49-60.PubMed ID:10388557
  • Patel, Y., Van Cott, E., Wilson, G. G., and McClelland, M. (1990). Cleavage at the twelve-base-pair sequence 5'-TCTAGATCTAGA-3' using M.XbaI (TCTAGm6A) methylation and DpnI (Gm6A/TC) cleavage. Nucl. Acids Res. 18:1603-1607.PubMed ID:2158082
  • Perler, F. B. and Efstratiadis, A. (1980). The Evolution of Genes: the Chicken Preproinsulin Gene. Cell 20:555-566.PubMed ID:7388949
  • Perler, F. B., and Karam, M. (1986). Cloning and characterization of two Onchocerca volvulus repeated DNA sequences. Mol. Biochem. Parasitol. 21:171-178.PubMed ID:3024001
  • Perler, F. B., Moon, A. M., Qiang, B.-Q., Meda, M., Dalton, M., Card, C., Schmidt-Ullrich, R., Wallach, D., Lynch, J., and Donelson, J. E. (1987). Cloning and characterization of an abundant Plasmodium knowlesi antigen which cross reacts with Gambian sera. Mol. Biochem. Parasitol. 25:185-193.PubMed ID:2444886
  • Perler, F. B., Comb, D. G., Jack, W. E., Moran, L. S., Qiang, B., Kucera, R. B., Benner, J., Slatko, B. E., Nwankwo, D. O., Hempstead, S. K., Carlow, C. K. S. and Jannasch, H. (1992) Intervening sequences in an Archaea DNA polymerase gene. Proc. Natl. Acad. Sci. USA 89:5577-5581.PubMed ID:1608969
  • Perler, F. B., Davis, E. O., Dean, G. E., Gimble, F. S., Jack, W. E., Neff, N., Noren, C. J., Thorner, J., and Belfort, M. (1994) Protein splicing elements: inteins and exteins - a definition of terms and recommended nomenclature. Nucl. Acids Res. 22:1125-1127.PubMed ID:8165123
  • Perler, F. B., Southworth, M. W., Wilbur, D. G., and Wallace, D. (1995). Typing marine vent thermophiles by DNA polymerase restriction fragement length polymorphisms. In: Archaea A Laboratory Manual, Robb, R.T. and Place, A.R., Eds. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY 3, 139-147.
  • Perler, F. B., Kumar, S., and Kong, H. (1996) Thermostable DNA Polymerases. In Enzymes and Proteins from Hyperthermophilic Microorganisms, Advs. Protein Chemistry, M.W.W. Adams, ed. (New York: Academic Press), pp. 377-435.
  • Perler, F. B., Olsen, G. J., and Adam, E. (1997) Compilation and analysis of intein sequences. Nuc. Acids Res. 25:1087-93.PubMed ID:9092614
  • Perler, F. B., Xu, M.-Q. and Paulus, H. (1997A) Protein splicing and autoproteolysis mechanisms. Curr. Opin. Chem. Biol. 1:292-299.
  • Perler, F. B. (1998) Protein Splicing of inteins and hedgehog autoproteolysis: structure, function and evolution. Cell 92:1-4. PubMed ID:9489693
  • Perler, F. B. (1998A). Breaking up is easy with esters [news; comment]. Nat Struct Biol. 5:249-252. PubMed ID:9546209
  • Perler, F. B. (1999). A natural example of protein trans-splicing. TIBS 24:209-211. PubMed ID:10366843
  • Perler, F. B. (1999A). InBase, the New England Biolabs Intein Database. Nuc. Acids Res. 27(1):346-347. PubMed ID:9847224
  • Perler, F.B., Xu, M. and Noren, C.J. (1999B). "Protein Splicing" In: The Encyclopedia of Molecular Biology, ed., Creighton, T.E., (John Wiley and Sons, New York) Vol 3, pages 2011-2016.
  • Perler, F.B. (2000). InBase, the Intein Database. Nuc. Acids Res. 28(1):344-345. PubMed ID:10592269
  • Perler, F.B. and Adam, E. (2000A). Protein splicing and its applications. Curr. Opin. Biotech. 11:377-383.
  • Perler, F.B. (2001). Hyperthermophilic Inteins. Methods Enzymol. 334:270-280.PubMed ID:11398469
  • Perler, F.B. (2002). InBase, the Intein Database. Nuc. Acids Res. 30(1):383-384. PubMed ID:11752343
  • Perler, F.B., Chen, L. and Southworth, M.W. (2002). The mechanism of protein splicing: variations on a theme. In Peptides: Proceedings of the Twnety-Seventh European Peptide Symposium (E. Benedetti and C. Pedone, eds.) Napoli, Italy, Edizioni Ziino, pages 254-255.
  • Petronzio, T., and Schildkraut, I. (1990). Altered specificity of restriction endonucleases HinfI. Nucl. Acids Res. 18:3666.PubMed ID:2362828
  • Philipp, M. (1984). Acetylcholinesterase secreted by intestinal nematodes: a reinterpretation of its putative role of "biochemical holdfast." Trans. Royal Soc Trop. Med. and Hyg. 78:138-139.
  • Philipp, M., and Davis, T. B. (1986). Biochemical and immunologic characterization of a major surface antigen of Dirofilaria immitis infective larvae. J. Immunol. 136 2621-2627.PubMed ID:2419445
  • Philipp, M., Davis , T. B., Storey, N., and Carlow, C. K. S. (1988). IMMUNITY IN FILARIASIS: Perspectives for Vaccine Development. Ann. Rev. Microbiol. 42:685-716.PubMed ID:3060005
  • Piessens, W. F., McReynolds, L. A. and Williams, S. A. (1987). Highly Repeated DNA Sequences as Species-specific Probes for Brugia. Parasitology Today 3(12):378-379.
  • Pingoud, V., Conzelmann, C., Kinzebach, S., Sudina, A., Metelev, V., Kubareva, E., Bujnicki, J.M., Lurz, R., Luder, G., Xu, S.Y. and Pingoud, A. (2003). PspGI, a type II restriction endonuclease from the extreme thermophile Pyrococcus sp.: structural and functional studies to investigate an evolutionary relationship with several mesophilic restriction enzymes. J. Mol. Biol. 329(5):913-929. PubMed ID:12798682
  • Polakiewicz, R.D., Schieferl, S.M., Dorner, L.F., Kansra, V. and Comb, M.J. (1998a). A Mitogen-activated Protein Kinase Pathway is Required for mu-Opioid Receptor Desensitization. J Biol Chem 273(20):12402-12406.PubMed ID:9575195
  • Polakiewicz, R.D., Schieferl, S.M., Gingras, A-C., Sonenberg, N. and Comb, M.J. (1998b). Mu-Opioid Receptor Activates Signaling Pathways Implicated In Cell Survival And Translational Control. J. Biol. Chem. 273:23534-23541.PubMed ID:9722592
  • Poland, B.W., Xu, M.Q. and Quiocho, F.L. (2000). Structural Insights into the Protein Splicing Mechanism of PI-SceI. J. Biol. Chem. 275:16408-16413.PubMed ID:10828056
  • Polisson, C., and Morgan, R. D. (1988). BsrI, a unique restriction endonuclease from Bacillus stearothermophilus which recognizes 5'ACTGG3'. Nucl. Acids Res. 16:5205.PubMed ID:2838810
  • Polisson, C., and Morgan, R. D. (1988). EarI, a restriction endonuclease from Enterobacter aerogenes which recognizes 5'CTCTTC3'. Nucl. Acids Res. 16:9872.PubMed ID:3263622
  • Polisson, C., and Morgan, R. D. (1988). AseI, a restriction endonuclease from Aquaspirillum serpens which recognizes 5'ATTAAT3'. Nucl. Acids Res. 16:10365.PubMed ID:3264065
  • Polisson, C., and Morgan, R. D. (1989). DrdI, a unique restriction endonuclease from Deinococcus radiodurans which recognizes 5'GACN6GTC3'. Nucl. Acids Res. 17:3316.PubMed ID:2542897
  • Polisson, C. (1989). MscI, a type II restriction endonuclease from Micrococcus species which recognizes 5' TGGCCA 3'. Nucl. Acids Res. 17:5858.PubMed ID:2788270
  • Polisson, C., and Morgan, R. D. (1990). AciI, a unique restriction endonuclease from Arthrobacter citreus which recognizes 5' CCGC3'. Nucl. Acids Res. 18:5911.PubMed ID:2170952
  • Polisson, C., and Robinson, D. (1992). ApoI, a unique restriction endonuclease from Arthrobacter protophormiae which recognizes 5' RAATTY-3'. Nucl. Acids Res. 20:2888.PubMed ID:1614876
  • Poole, C. B., Grandea, A. G., III, Maina, C. V., Jenkins, R. E., Selkirk, M. E., and McReynolds, L. A. (1992). Cloning of a cuticular antigen that contains multiple tandem repeats from the filarial parasite Dirofilaria immitis. Proc Natl Acad Sci U S A. 89:5986-5990.PubMed ID:1631084
  • Poole, C. B., Hornstra, L. J., Benner, J. S., Fink, J. R., and McReynolds, L. A. (1996). Carboxy-terminal sequence divergence and processing of the polyprotein antigen from Dirofilaria immitis1. Molec. Biochem. Parasitol. 82:51-65.PubMed ID:8943150
  • Poole, C. B., Jin, J. and McReynolds, L. A. (2003). Cloning and Biochemical Characterization of Blisterase, a Subtilisin-like Convertase from the Filarial Parasite, Onchocerca volvulus. J. Biol. Chem. 278(38):35183-36190.PubMed ID:12855702
  • Posfai, J., Szaraz, Z., and Roberts, R. J. (1994). VISA: Visual Sequence Analysis for the comparison of multiple amino acid sequences. CABIOS 10:537-544.PubMed ID:7828070
  • Pradhan, S., Talbot, D., Sha, M., Benner, J., Hornstra, L., Li, E., Jaenisch, R. and Roberts, R. J. (1997). Baculovirus-Mediated Expression and Characterization of the Full-Length Murine DNA Methyltransferase. Nuc. Acids Res. 22:4666-4673. PubMed ID:9358180
  • Pradhan, S., Cummings, M., Roberts, R. J. and Adams, R. L. P. (1998). Isolation, Characterization and Baculovirus-Mediated Expression of the cDNA Encoding Cytosine DNA Methyltransferase from Pisum Sativum. Nuc. Acids Res. 26:1214-1222. PubMed ID:9469828
  • Pradhan, S., Urwin, N.A., Jenkins, G.I. and Adams, R.L. (1999). Effect of CWG methylation on expression of plant genes. Biochem J. 341:473-476.PubMed ID:10417307
  • Pradhan, S., Bacolla, A., Wells, R.D. and Roberts, R.J. (1999). Recombinant Human DNA (Cytosine-5) Methyltransferase. I. expression, purification, and comparison of de novo and maintenance. J. Biol. Chem. 274:33002-33010.PubMed ID:10551868
  • Pradhan, S and Roberts, R.J. (2000). Hybrid mouse-prokaryotic DNA (Cytosine-5) methyltransferase retain the specificity of the parental C-terminal domain. EMBO J. 19:2103-2114.PubMed ID:10790376
  • Pradhan, S. and Kim, G.-D. (2002). The retinoblastoma gene product interacts with maintenance human DNA (Cytosine-5) methyltransferase and modulates its activity. EMBO J. 21(4):779-788.PubMed ID:11847125
  • Pradhan, S. and Esteve P.-O. (2003). Allosteric Activator Domain of Maintenance Human DNA (Cytosine-5) Methyltransferase and Its Role in Methylation Spreading. Biochemistry 42(18):5321-5332.PubMed ID:12731873
  • Pradhan, S. and Esteve P.-O. (2003). Mammalian DNA (cytosine-5) methyltransferases and their expression. Clin. Immunol. 109(1):6-16.PubMed ID:14585271
  • Punkosdy, G.A., Dennis, V.A., Lasater, B.L., Tzertzinis, G. foster, J.M. and Lammie, P.J. (2001). Detection of Serum IgG Antibodies Specific for Wolbachia Surface Protein in Rhesus Monkeys Infected with Brugia malayi. J Infectious Diseases 184:385-389.PubMed ID:11443570
  • Qian, X., Guan, C. and Guo, H.-C. (2003). A Dual Role for an Aspartic Acid in Glycosylasparaginase Autoproteolysis. Structure 11:997-1003.PubMed ID:12906830
  • Qiang, B. Q., and Schildkraut, I. (1984). A type II restriction endonuclease with an eight nucleotide specificity from Streptomyces fimbriatus. Nucleic Acids Res. 12:4507-4516.PubMed ID:6330673
  • Qiang, B. Q., and Schildkraut, I. (1986). Two unique restriction endonucleases from Neisseria lactamica. Nucl. Acids Res. 14:1991-1999.PubMed ID:3008082
  • Qiang, B.-Q., and Schildkraut, I. (1987). NotI and SfiI: restriction endonucleases with octanucleotide recognition sequences. Methods Enzymol. 155:15-21.PubMed ID:2828862
  • Raghavan, N., McReynolds, L. A., Maina, C. V., Feinstone, S. M., Jayaraman, K., Ottesen, E., and Nutman, T. B. (1991). Characterization of a recombinant clone of Wuchereria bancrofti with specificity for human lymphatic filarial parasites. Mol. Biochem. Parasitol. 47:63-71.PubMed ID:1857386
  • Raghavan, N., Maina, C. V., Fitzgerald, P. C., Tuan, R. S., Slatko, B. E., Ottesen, E. A., and Nutman, T. B. (1992). Characterization of a muscle-associated antigen from Wuchereria bancrofti. Exp. Parasitol. 75:379-389.PubMed ID:1283597
  • Rajski, S.R., Kumar, S., Roberts, R.J. and Barton, J.K. (1999). Protein-Modulated DNA Electron Transfer. J. Am. Chem. Soc. 121:5615-5616.
  • Raleigh, E. A., and Wilson, G. (1986). Escherichia coli K-12 restricts DNA containing 5-methylcytosine. Proc. Natl. Acad. Sci. USA 83:9070-9074.PubMed ID:3024165
  • Raleigh, E. A. (1987). Restriction and modification in vivo by Escherichia coli K12. Methods Enzymol. 152:130-141.PubMed ID:2821354
  • Raleigh, E. A., Murray, N. E., Revel, H., Blumenthal, R. M., Westaway, D., Reith, A. D., Rigby, P. W. J., Elhai, J., and Hanahan, D. (1988). McrA and McrB restriction phenotypes of some E. coli strains and implications for gene cloning. Nucl. Acids Res. 15:1563-1575.PubMed ID:2831502
  • Raleigh, E. A., Trimarchi, R., and Revel, H. (1989). Genetic and physical mapping of the mcrA (rglA) and mcrB (rglB) loci of Escherichia coli K-12. Genetics 122:279-296.PubMed ID:2548920
  • Raleigh, E. A., Benner, J., Bloom, F., Braymer, H. D., DeCruz, E., Dharmalingam, K., Heitman, J., Noyer-Weidner, M., Piekarowicz, A., Kretz, P. L., Short, J. M., and Woodcock, D. (1991). Nomenclature relating to restriction of modified DNA in Escherichia coli. J. Bacteriol. 173:2707-2709.PubMed ID:2013582
  • Raleigh, E. A. (1992). Organization and function of the mcrBC genes of Escherichia coli K-12. Mol. Microbiol 6:1079-1086.PubMed ID:1316984
  • Raleigh, E., Dila, D., Sutherland, E., Kelleher, J., Moran, L., Slatko, B., and Briggs, P. (1993). McrBC, a novel multisubunit GTP-dependent restriction endonuclease. J. Cell Biochem. Suppl. 17C, 152.
  • Raleigh, E. A. and Brooks, J. E (1998). Restriction Modification Systems: Where They Are and What They Do. Bacterial Genomes 78-92. F. J. de Bruijn, J. R. Lupski and G. M. Weinstock eds. (Chapman & Hall).
  • Rao, V., Guan, C., and Van Roey, P. (1995). Crystal structure of endo-beta-N-acetylglucosaminidase H at 1.9 A resolution: active-site geometry and substrate recognition. Structure 3:449-457.PubMed ID:7663942
  • Rao, V., Cui, T., Guan, C., and Van Roey, P. (1999). Mutations of endo-B-N-acetylglucosaminidase H active site residues Asp130 and Glu132: Activities and conformations. Protein Sci. 3:449-457.
  • Rees, P. A., Nwankwo, D. O., Wilson, G. G., and Benner, J. S. (1988). Cloning, purification and characterization of the HincII and HindII methyltransferases from Haemophilus influenzae. Gene 74:37.PubMed ID:3074015
  • Reinecke, S. N., and Morgan, R. D. (1991). BfaI, a new MaeI isoschizomer from Bacteroides fragilis, recognizes the sequence 5' C^TAG 3'. Nucl. Acids Res. 19:1152.PubMed ID:2020550
  • Renbaum, P., Abrahamove, D., Fainsod, A., Wilson, G. G., Rottem, S., and Razin, A. (1990). Cloning, characterization, and expression in Escherichia coli of the gene coding for the CpG DNA methylase from Spiroplasma sp. strain MQ1(M.SssI). Nucl. Acids Res. 18:1145-1152.PubMed ID:2181400
  • Riggs, P. Detection and Isolation of Recombinant Protein Based on Binding Affinity Reporter, Meth. Molec. Biol. 63:85-101. (R. Tuan Humana Press, Inc.)
  • Riggs, P. (2000). Expression and purification of recombinant proteins by fusion to maltose-binding protein. Mol. Biotechnol. 15(1):51-63.PubMed ID:10911622
  • Roberts, R.J. and Macelis, D. (1993). REBASE-restriction enzymes and methylases. Nucl. Acids Res. 21:3125-3137.PubMed ID:8392714
  • Roberts, R.J. and Halford, S.E. (1993). Type II Restriction Endonucleases, Nucleases, 2nd Edition, 35 - 88. S. M. Linn, R. S. Lloyd and R. J. Roberts, eds. (Cold Spring Harbor: Cold Spring Harbor Laboratory Press).
  • Roberts, R.J. and Macelis, D. (1993). The Restriction Enzymes., Nucleases, 2nd Edition, 439-444. S. M. Linn, R. S. Lloyd and R. J. Roberts, eds. (Cold Spring Harbor: Cold Spring Harbor Laboratory Press).
  • Roberts, R.J. (1994). An amazing distortion in DNA induced by a methyltransferase (Nobel lecture). Angew. Chem. Int. Ed. Engl. 33:1222-1228.
  • Roberts, R.J. (1994). An amazing distortion in DNA induced by a methyltransferase (Nobel lecture). Bioscience Reports 14(3):103-117.
  • Roberts, R.J. and Macelis, D. (1994). REBASE - restriction enzymes and methylases. Nucl. Acids. Res. 22:3628-3639.PubMed ID:7937073
  • Roberts, R.J. (1995). On base flipping. Cell 82:9-12.PubMed ID:7606789
  • Roberts, R.J. and Macelis, D. (1996). REBASE--restriction enzymes and methylases. Nucl. Acids Res. 24:223-235.PubMed ID:8594587
  • Roberts, R.J. (1996). Teaching About Science, Accountability in Research, Volume 5, 45-50 (Overseas Publishers Association).
  • Roberts, R.J. and Macelis, D. (1997). REBASE-restriction enzymes and methylases. Nucl. Acids Res. 25:248-262.PubMed ID:9016548
  • Roberts, R.J. and Macelis, D. (1998). REBASE-restriction enzymes and methylases. Nucl. Acids Res. 26:338-350.PubMed ID:9399870
  • Roberts, R.J. and Cheng, X. (1998). Base Flipping. Annual Review Biochem. 67:181-198.
  • Roberts, R.J. and Macelis, D. (1999). REBASE-restriction enzymes and methylases. Nucl. Acids Res. 27(1):312-313.PubMed ID:9847213
  • Roberts, R.J. (2000). The early days of bioinformatics publishing. Bioinformatics 16(1):2-4.PubMed ID:10812470
  • Roberts, R.J. and Macelis, D. (2000A). REBASE-restriction enzymes and methylases. Nucl. Acids Res. 28(1):306-307.PubMed ID:10592256
  • Roberts, R.J., and Macelis, D. (2001). REBASE-restriction enzymes and methylases. Nucl. Acids Res. 29(1):268-269.<PubMed ID:11125108
  • Roberts, R.J., Varmus, H.D., Ashburner, M., Brown, P.O., Eisen, M.B., Khosla, C., Kirschner, M., Nusse, R., Scott, M. and Wold, B. (2001A). Information access. Building a "GenBank" of the published literature. Science 291(5512):2318-2319.PubMed ID:11269300
  • Roberts, R.J. (2001B). PubMed Central: The GenBank of the Published Literature. Proc. Natl. Acad. Sci. 98:381-382.PubMed ID:11209037
  • Roberts, R.J., Belfort, M. et al. (2003). A nomenclature for restriction enzymes, DNA methyltransferases, homing endonucleases and their genes. Nucl. Acids Res. 31(7):1805-1812. PubMed ID:12654995
  • Roberts, R.J., Vincze, T., Posfai, J. and Macelis, D. (2003A). REBASE Restriction enzymes and methyltransferases. Nucl. Acids Res. 31:418-420. PubMed ID:12520038 A NAME="rodicio1994">
  • Rodicio, M. R., Quinton-Jager, T., Moran, L. S., Slatko, B. E., and Wilson, G. G. (1994). Organization and sequence of the SalI restriction-modification system. Gene 151:167-172.
  • Ruan, H., Lunnen, K. D., Scott, M. E., Moran, L. S., Slatko, B. E., Pelletier, J. J., Hess, E. J., Benner, J., Wilson, G. G., and Xu, S. Y. (1996). Cloning and sequence comparison of AvaI and BsoBI restriction-modification systems. Mol. Gen. Genet. 252:695-699.PubMed ID:8917312
  • Ruan, H., Lunnen, K. D., Pelletier, J. J., and Xu, S. Y. (1997). Overexpression of BsoBI restriction endonuclease in E. coli, purification of the recombinant BsoBI, and identification of catalytic residues of BsoBI by random mutagenesis. Gene 188:35-39.PubMed ID:9099856
  • Samuelson, J.C. and Xu, S. Y. (2002). Directed Evolution of Restriction Endonuclease BstYI to Achieve Increased Substrate Specificity. J. Mol. Biol. 319:673-683.PubMed ID:12054862
  • Sandman, K., Perler, F. B., and Reeve, J. N. (1994). Histone-encoding genes from Pyrococcus: evidence for members of the HMf family of archaeal histones in a non-methanogenic Archaeon*. Gene 150:207-208.PubMed ID:7959058
  • Sandman, K.E., Benner, J.S. and Noren, C.J. (2000). Phage Display of Selenopeptides. J. Amer. Chem. Soc. Feb 9, 2000.
  • Sandman, K.E. and Noren, C.J. (2000A). The efficiency of Escherichia coli selenocysteine insertion is influenced by the immediate downstream nucleotide. Nucl. Acids Res. 28(3):755-761.PubMed ID:10637327
  • Sandman, K.E., Tardiff, D.F., Neely, L.A. and Noren, C.J. (2003). Revised Escherichia coli selenocysteine insertion requirements determined by in vivo screening of combinatorial libraries of SECIS variants. Nucl. Acids Res. 31:2234-2241.PubMed ID:12682374
  • Schildkraut, I., Banner, C. D. B., Rhodes, C. S., and Parekh, S. (1984). The cleavage site for the restriction endonuclease EcoRV is 5'-GAT^ATC-3'. Gene 27:327-329.PubMed ID:6329909
  • Schildkraut, I. (1984). Screening for and characterizing restriction endonucleases., Genetic Engineering 6:117-139, J. K. Setlow and A. Hollaender, eds. (New York: Plenum).
  • Schildkraut, I., Lynch, J., and Morgan, R. (1987). The cleavage site for the restriction endonucleases BanI and HgiCI is 5' ...G^GPyPuCC ...3'. Nucl. Acids Res. 15:5492.PubMed ID:3037499
  • Schildkraut, I. (1993). Compilation of Commercially Available Nucleases, Nucleases, 2nd Ed. pgs 469-483 (Cold Spring Harbor: Cold Spring Harbor Laboratory Press).
  • Schluckebier, G., Labahn, J., Granzin, J., Schildkraut, I., and Saenger, W. (1995). A model for DNA binding and enzyme action derived from crystallographic studies of the TaqI N6-adenine-methyltransferase. Gene 157:131-134.PubMed ID:7607476
  • Sears, L. E., Moran, L. S., Kissinger, C., Creasey, T., Perry-O'Keefe, H., Roskey, M., Sutherland, E., and Slatko, B. E. (1992). CircumVent» Thermal Cycle Sequencing and Alternative Manual and Automated DNA Sequencing Protocols Using the Highly Thermostable VentR» (exo-) DNA Polymerase. BioTechniques 13:626-633.PubMed ID:1476733
  • Sears, L. E., Zhou, B., Aliotta, J. M., Morgan, R. D., and Kong, H. M. (1996). Bael, another unusual Bcgl-like restriction-endonuclease. Nucl. Acids Res. 24:3590-3592.PubMed ID:8836187
  • Serva, S., Weinhold, E., Roberts R.J. and Klimasauskas S. (1998). Chemical display of thymine residues flipped out by DNA methyltransferases. Nucl. Acids Res. 26:3473-3479.PubMed ID:9671807
  • Shao, Y., Xu, M.Q. and Paulus, H. (1995). Protein splicing: Chracterization of the aminosuccinimide residue at the carboxyl terminus of the excised intervening sequence. Biochemistry 34:10844-10850.PubMed ID:7662664
  • Shao, Y., Xu, M. Q., and Paulus, H. (1996). Protein Splicing: Evidence for an N-O Acyl Rearrangement as the Initial Step in the Splicing Process. Biochemistry 35:3810-3815.PubMed ID:8620003
  • Sharma, S., Zhang, A., Wang, H., Harcum, S.W. and Chong S. (2003). Study of protein splicing and intein-mediated peptide bond cleavage under high-cell-density conditions. Biotechnol. Prog. 19(3):1085-1090.PubMed ID:12790686
  • Silber, K.R., Polisson, C., Rees, P.A., and Benner, J.S. (1988). Cloning, purification and characterization of the M.NdeI methyltransferase from Neisseria denitrificans. Gene 74:43-44.PubMed ID:3074017
  • Slatko, B. E., Benner, J. S., Jager-Quinton, T., Moran, L. S., Simcox, T. G., VanCott, E. M., and Wilson, G. G. (1987). Cloning, sequencing and expression of the TaqI restriction-modification system. Nucl. Acids Res. 15:9781-9796.PubMed ID:2827113
  • Slatko, B. E., Croft, R., Moran, L. S., and Wilson, G. G. (1988). Cloning and analysis of the HaeIII and HaeII methyltransferase genes. Gene 74:45-50.PubMed ID:3248732
  • Slatko, B. (1994). Thermal cycle Dideoxy DNA Sequencing. Methods Molec. Biol. 58:413-423.
  • Slatko, B., Heinrich, P., Nixon, B. T., Eckert, R. L., Albright, L., and Ausubel, F. (1994). DNA sequencing. In: Current protocols in molecular biology. (Ausubel, F.M., Brent, R., Kingston, R.E., Moore, D.D., Seidman, J.G., Smith, J.A. and Struhl, K., Eds.) John Wiley & Sons, New York. Chapter 7, 7.0.1-7.6.13.
  • Slatko, B. E. (1994). Thermal cycle dideoxy DNA sequencing, Methods Molec. Biol. 31:35-45.PubMed ID:7921032
  • Slatko, B. E. (1996). Thermal cycle dideoxy DNA sequencing, Mol. Biotechnol. 6:311-322.PubMed ID:9067976
  • Slatko, B.E., O'Neill, S.L., Scott, A.L., Werren, J.L., Blaxter, M.L. and the Wolbachia genome Consortium (1999). The Wolbachia Genome Consortium. Microbiol. and Comparative Genomics 4(3):161-165.
  • Sluder, A.E., Mathews, S.W., Hough, D., Yin, V.P. and Maina, C.V. (1999). The Nuclear Receptor Superfamily Has Undergone Extensive Proliferation and Diversification in Nematodes. Genome Res. 9:103-130.PubMed ID:10022975
  • Sluder, A.E. and Maina, C.V. (2001). Nuclear receptors in nematodes: themes and variations. Trends in Genetics 17(4):206-213.
  • Sohail, A., Ives, C. L., and Brooks, J. E. (1995). Purification and characterization of C.BamHI, a regulator of the BamHI restriction-modification system. Gene 157:227-228.PubMed ID:7607495
  • Southworth, M. W., Kong, H., Kucera, R. B., Ware, J., Jannasch, H. W., and Perler, F. B. (1996). Cloning of thermostable DNA polymerases from hyperthermophilic marine Archaea with emphasis on Thermococcus sp. 9 degrees N-7 and mutations affecting 3'-5' exonuclease activity. Proc Natl Acad Sci 93:5281-5285.PubMed ID:8643567
  • Southworth, M. W., Fuhrman, J. A., Robbins, P. W., Beauregard, K., and Perler, F. B. (1996). Gene cloning and production of active recombinant Brugia Malayi microfilarial chintinase. Gene 177:55-58.PubMed ID:8921845
  • Southworth, M. W., Adam, E., Panne, D., Byer, R., Kautz, R. and Perler, F. B. (1998). Control of protein splicing by intein fragment reassembly. EMBO J 17:918-926.PubMed ID:9463370
  • Southworth, M. W., Amaya, K., Evans, T. C., Xu, M-Q and Perler, F. B. (1999). Purification of Proteins Fused to Either the Amino or Carboxy Terminus of the Mycobacterium xenopi Gyrase A Intein. BioTechniques 27(1):110-120.PubMed ID:10407673
  • Southworth, M. W., Benner, J. and Perler, F. B. (2000). An alternative protein splicing mechanism for inteins lacking an N-terminal nucleophile. EMBO J 19(18):5019-5026.PubMed ID:10990465
  • Southworth, M. W., Amaya, K., Evans, T. C., Xu, M. Q. and Perler, F. B. (2001). Purification of proteins fused to either the amino or carboxy terminus of the Mycobacterium xenopi gyrase A intein. In Cloning and Expression vectors for Gene Function Analysis (Q. Lu and M. Weiner, Eds.) Eaton Publishing, pp.55-59.
  • Southworth, M.W. and Perler, F.B. (Nov 2002). Protein Splicing of the Deinococcus radiodurans Strain R1 Snf2 Intein. J. Bacteriol. 184(22):6387-6388. PubMed ID:12399510
  • Southworth, M.W. and Perler, F.B. (Nov 2002A). Inteins in microbial genomes: distribution, mechanism and function. ScientificWorldJournal 2(Supp 2): 25-26.PubMed ID:14532441
  • Steel, C., Limberger, R. J., McReynolds, L. A., Ottesen, E. A., and Nutman, T. B. (1990). B CELL RESPONSES TO PARAMYOSIN. Isotypic Analysis and Epitope Mapping of Filarial Paramyosin in Patients with Onchocerciasis. J. Immunol. 145:3917-3923.PubMed ID:1701001
  • Stewart, F. J. and Raleigh, E. A. (1998). Dependence of McrBC Cleavage on Distance Between Recognition Elements. Biol. Chem. 379,611-616. PubMed ID:9628366
  • Stewart, F.J., Panne, D., Bickle, T.A. and Raleigh, E.A. (2000). Methyl-specific DNA Binding by McrBC, a Modification-dependent Restriction Enzyme. J. Mol. Biol. 298:611-622.PubMed ID:10788324
  • Storey, N. and Philipp, M. (1992). Brugia malayi: patterns of expression of surface-associated antigens. Exp Parasitol 74:57-68.PubMed ID:1730272
  • Strzelecka, T., Newman, M., Dorner, L. F., Knott, R., Schildkraut, I., and Aggarwal, A. K. (1994). Crystallization and Preliminary X-ray Analysis of Restriction Endonuclease BamHI-DNA Complex. J. Mol. Biol. 239:430-432.PubMed ID:8201623
  • Sun, L.V., Foster, J.M., Tzertzinis, G., Ono, M., Bandi, C., Slatko, B.E. and O'Neill, S.L. (2001). Determination of Wolbachia Genome Size by Pulsed-Field Gel Electrophoresis. J. Bacteriol. 183(7):2219-2225.PubMed ID:11244060
  • Sun, L., Ghosh, I., Paulus, H. and Xu, M.Q. (2001). Protein trans-Splicing To Produce Herbicide-Resistant Acetolactate Synthase. Appl. Env. Microbiol. 67(3):1025-1029.PubMed ID:11229887
  • Sun, L., Ghosh, I. and Xu, M.Q. (2003). Generation of an affinity column for antibody purification by intein-mediated protein ligation. J. Immunol. Methods 282(1-2):45-52.PubMed ID:14604539
  • Soundararajan, M., Chang, Z., Morgan, R.D., Heslop, P. and Connolly, B.A. (2002). DNA Binding and Recognition by the IIs Restriction Endonuclease MboII. J. Biol. Chem. 277(2):887-895.PubMed ID:11606594
  • Sutherland, E., Coe, L., and Raleigh, E. A. (1992). McrBC: a multisubunit GTP-dependent restriction endonuclease. J. Mol. Biol. 225:327-348.PubMed ID:1317461
  • Sznyter, L. A., Slatko, B., Moran, L., O'Donnell, K. H., and Brooks, J. E. (1987). Nucleotide sequence of the DdeI restriction-modification system and characterization of the methylase protein. Nucl. Acids Res. 15:8249-8266.PubMed ID:2823226
  • Sznyter, L. A., and Brooks, J. E. (1988). The characterization and cloning of the EagI restriction-modification system. Gene 74:53.PubMed ID:3266860
  • Szybalski, W., Blumenthal, R. M., Brooks, J. E., Hattman, S., and Raleigh, E. A. (1988). Nomenclature for bacterial genes coding for class-II restriction endonucleases and modification methyltransferases. Gene 74:279-280.PubMed ID:3266859
  • Tan, Y., Low, K. G., Boccia, C., Grossman, J., and Comb, M. J. (1994). Fibroblast growth factor and cyclic AMP (cAMP) synergistically active gene expression at a cAMP response element. Mol. Cell. Biol. 14:7546-7556.PubMed ID:7935470
  • Tan, Y., Rouse, J., Zhang, A., Cariati, S., Cohen, P., and Comb, M. J. (1996). FGF and stress regulate CREB and ATF-1 via a pathway involving p38 MAP kinase and MAPKAP kinase-2. EMBO J 15:4629-4642.PubMed ID:8887554
  • Taron, C. H., Benner, J. S., Hornstra, L. J., and Guthrie, E. P. (1995). A novel beta-galactosidase gene isolated from the bacterium Xanthomonas manihotis exhibits strong homology to several eukaryotic beta-galactosidases. Glycobiology 5:603-610.PubMed ID:8563148
  • Taron, C. H., Van Cott, E. M., Wilson, G. G., Moran, L. S., Slatko, B. E., Hornstra, L. J., Benner, J. S., Kucera, R. B., and Guthrie, E. P. (1995). Cloning and expression of the NaeI restriction endonuclease-encoding gene and sequence analysis of the NaeI restriction-modification system. Gene 155:19-25.PubMed ID:7698663
  • Telenti, A., Southworth, M., Alcaide, F., Aauglat, S., Jacobs Jr., W. R., and Perler, F. B. (1997). The Mycobacterium xenopi GyrA Protein Splicing Element: Characterization of a Minimal Intein. J. Bacteriol. 179:6378-6382.PubMed ID:9335286
  • Theriault, G., Roy, P. H., Howard, K. A., Benner, J. S., Brooks, J. S., Waters, A. F., and Gingeras, T. R. (1985). Nucleotide sequence of the PaeR7 restriction/modification system and partial characterization of its protein products. Nucl. Acids Res. 13:8441-8461.PubMed ID:3001639
  • Toure, F. S., Bain, O., Nerrienet, E., Millet, P., Wahl, G., Toure, Y., Doumbo, O., Nicolas, L., Georges, A. L., McReynolds, L. A., and Egwang, T. G. (1997). Detection of Loa loa-specific DNA in Blood from Occult-Infected Individuals. Exp. Parasitol. 86:163-170.PubMed ID:9225766
  • Tuan, R. S., Shepley, K. J., M.M., M., Abraham, D., and Perler, F. B. (1991). Histochemical localization of gene expression in Onchocerca volvulus: in situ DNA histohybridization and immuno-cytochemistry. Mol. Biochem. Parasitol. 49:191-203.PubMed ID:1775163
  • Tuckey, C.D. and Noren, C.J. (2002). Selection for mutants improving expression of an anti-MAP kinase monoclonal antibody by filamentous phage display. J. Immunol. Methods 270:247-257.PubMed ID:12379329
  • Tweedie, S., Paxton. W, A., Ingram, L., Maizels, R. M., McReynolds, L. A., and Selkirk, M. E. (1993). Brugia pahangi and Brugia malayi: A Surface-Associated Glycoprotein (gp15/400) is Composed of Multiple Tandemly Repeated Units and Processed from a 400-kDa Precursor1. Exp. Parasitol. 76:156-164.PubMed ID:8454024
  • Vaisvila, R., Rasmussen, L.J., Lobner-Olsen, A., von Freisleben, U. and Marinus, M.G. (2000). The LipB protein is a negative regulator of dam gene expression in Escherichia coli. Biochim. Biophys. Acta. 1494(1-2):43-53.PubMed ID:11072067
  • Vaisvila, R., Morgan, R.D., Posfai, J. and Raleigh, E.A. (2001). Discovery and distribution of super-integrons among pseudomonads. Mol. Microbiol. 42(3):587-601.PubMed ID:11722728
  • Vanamee, E.S., Hsieh, P.C., Zhu, Z., Yates, D., Garman, E., Xu, S.Y. and Aggarwal, A.K. (2003). Glucocorticoid Receptor-like Zn(Cys)4 Motifs in Bsl I Restriction Endonuclease. J. Mol. Biol. 334:595-603.
  • Van Cott, E. M., and Wilson, G. G. (1988). Cloning the FnuDI, NaeI, NcoI and XbaI restriction-modification systems. Gene 74:55-59.PubMed ID:3074019
  • van der Woerd, M.J., Pelletier, J.J., Xu, S. and Friedman, A.M. (2001). Restriction enzyme BsoBI-DNA complex: a tunnel for recognition of degenerate DNA sequences and potential histidine catalysis. Structure 9(2):133-144.PubMed ID:11250198
  • Van Roey, P., Silva, G. H., Rao, V., Plummer, J., T.H., Tarention, A. L., and Guan, C. (1994). Crystallization and Preliminary Crystallographic Analysis of Two Endo-b-N-acetylglucosaminidases, Endo H and Endo F1. J. Mol. Biol. 237:157-159.PubMed ID:8133514
  • Vargas-Serrato, E., Barnwell, J.W., Ingravallo, P., Perler, F.B. and Galinski, M.R. (2002). Merozoite surface protein-9 of Plasmodium vivax and related simian malaria parasites is orthologous to p101/ABRA of P. falciparum. Mol. Biochem. Parasitol. 120(1):41-52.PubMed ID:11849704
  • Venter, J.C., Roberts, R.J. et al. (2001). The sequence of the human genome. Science 291:1304-1351.PubMed ID:11181995
  • Viadiu, H., Kucera, R., Schildkraut, I. and Aggarwal, A.K. (2000). Crystallization of Restriction Endonuclease BamHI with Nonspecific DNA. J. Struct. Biol. 130:81-85.PubMed ID:10806094
  • Vincze, T., Posfai, J. and Roberts, R.J. (2003). NEBcutter: A program to cleave DNA with restriction enzymes. Nucl. Acids Res. 31:3688-3691. PubMed ID:12824395
  • Vitor, J. M. B., Polisson, C., Cabrita, J., and Silva, R. V. C. (1993). Restriction enzymes from Campylobacter coli strains. Acta gastroenterol. belg. 56, 41.
  • Vitor, J. M., and Morgan, R. D. (1995). Two novel restriction endonucleases from Campylobacter jejuni. Gene 157:109-110.PubMed ID:7607469
  • Wah, D. A., Hirsch, J. A., Dorner, L. F., Schildkraut, I., Aggarwal, A. K. (1997). Structure of the Multimodular Endonuclease FokI Bound to DNA. Nature 388(6637):97-100.PubMed ID:9214510
  • Wah, D. A., Bitinaite, J., Schildkraut, I., Aggarwal, A. K. (1998). Structure of FokI has Implications for DNA Cleavage. Proc. Natl. Acad. Sci. USA 95(18):10564-10569.PubMed ID:9724743
  • Waite-Rees, P. A., Keating, C. J., Moran, L. S., Slatko, B. E., Hornstra, L. J., and Benner, J. S. (1991). Chacterization of Expression of the Escherichia coli Mrr Restriction System. J. Bacteriol. 173:5207-5219.PubMed ID:1650347
  • Wang, H. and Chong, S. (2003). Visualization of coupled protein folding and binding in bacteria and purification of the heterodimeric complex.Proc. Natl. Acad. Sci. USA 100(2):478-483.PubMed ID:12515863
  • Ware, J.L., Moran, L., Lin, C.-L. and Slatko, B. (2000). Implementation of Automation in a Small-Scale DNA Sequencing Core Facility. J. Biomolecular Techniques 11:151-154.
  • Ware, J., Moran, L., Foster, J., Posfai, J., Vincze, T., Guiliano, D., Blaxter, M., Eisen, J. and Slatko, B. (2002). Sequencing and analysis of a 63 kb bacterial artificial chromosome insert from the Wolbachia endosymbiont of the human filarial parasite Brugia malayi. Int. J. Parasitol. 32(2):159-166.PubMed ID:11812492
  • Watson, R. J., Schildkraut, I., Qiang, B. Q., Martin, S. M., and Visentin, L. P. (1982). NdeI: a restriction endonuclease from Neisseria denitrificans which cleaves DNA at 5'-CATATG-3' sequences. FEBS Lett. 150:114-116.PubMed ID:6297965
  • Wayne, J., and Xu, S. Y. (1997). Identification of a thermophilic plasmid origin and its cloning within a new Thermus-E. coli shuttle vector. Gene 195:321-328.PubMed ID:9305778
  • Wayne, J., Holden, M., and Xu, S. Y. (1997). The Tsp45I restriction-modification system is plasmid-borne within its thermophilic host. Gene 202:83-88.PubMed ID:9427549
  • Wei, A., Yuan, A., Fawcett, G., Butler, A., Davis, T., Xu, S.Y. and Salkoff, L. (Oct 2002). Efficient isolation of targeted Caenorhabditis elegans deletion strains using highly thermostable restriction endonucleases and PCR. Nucleic Acids Res. 30(20):e110.PubMed ID:12384612
  • Weng, Q.-P., Kozlowski, M., Belham, C., Zhang, A., Comb, M. J., Avruch, J. (1998). Regulation of the p70 S6 Kinase by Phosphorylation in Vivo. J. Bio. Chem. 273(26):16621-16629.PubMed ID:9632736
  • Whitaker, R. D., Dorner, L. F. and Schildkraut, I. (1999). A Mutant of BamHI Restriction Endonuclease which Requires N6-Methyladenine for Cleavage. J. Mol. Biol. 285:1525-1536.PubMed ID:9917394
  • Wilkie, S. D. and Landry, D. (1998). Determination of Certain Agarose-Immobilized Ligands by Use of Perchloric Acid. Biochromatography 3:205-214.
  • Williams, S. A., Slatko, B. E., Moran, L. S., and DeSimone, S. M. (1986). Sequencing in the Fast Lane: A Rapid Protocol for [a-35S] dATP Dideoxy DNA Sequencing. BioTechniques 4:138-147.
  • Williams, S. A., DeSimone, S. M., and McReynolds, L. A. (1988). Species-specific oligonucleotide probes for the identification of human filarial parasites. Mol. Biochem. Parasitol. 28:163-169.PubMed ID:3367934
  • Williams, S. A., Poole, C.B., Landry, D., Glover, J., and McReynolds, L. A. (1993). Brugia malayi and Brugia pahangi: synthetic biotin labeling of oligonucleotide probes for use in species-specific detection assays. Exp, Parasitol. 77:235-245.PubMed ID:8375491
  • Williams, S. A. (1993). Workshop of DNA Probes and PCR for Detection of Filarial Parasies in Vectors (New England Biolabs, Beverly, MA) pp. 1-27.
  • Williams, S.A., Lizotte-Waniewski, M.R., Foster, J., Guiliano, D., Daub, J., Scott, A.L., Slatko, B. and Blaxter, M.L. (2000). The filarial genome project: analysis of the nuclear, mitochondrial and endosymbiont genomes of Brugia malayi. Int. J. Parasitol. 30:411-419.PubMed ID:10731564
  • Williamson, D. H., Wilson, R. J., Bates, P. A., McCready, S., Perler, F., and Qiang, B. Q. (1985). Nuclear and Mitochondrial DNA of the Primate Malarial Parasite Plasmodium Knowlesi. Mol Biochem Parasitol. 14:199-209.PubMed ID:2985981
  • Wilson, G. G. (1988). Type II restriction-modification systems. Trends Genet. 4:314-318.PubMed ID:3070854
  • Wilson, G. G. (1988). Cloned restriction-modification systems - a review. Gene 74:281-289.PubMed ID:3074014
  • Wilson, G. G. (1991). Organization of restriction-modification systems. Nucl. Acids Res. 19:2539-2566.PubMed ID:2041731
  • Wilson, G. G., and Murray, N. E. (1991). Restriction and Modification Systems. Ann. Rev. Genet. 25:585-627.PubMed ID:1812816
  • Wilson, G. G. (1992). Amino acid sequence arrangements of DNA-methyltransferases. Methods Enzymol. 216:259-279.PubMed ID:1479903
  • Wong-Madden, S. T., and Landry, D. (1995). Purification and characterization of novel glycosidases from the bacterial genus Xanthomonas. Glycobiology 5:19-28.PubMed ID:7772864
  • Wong-Madden, S. T., Landry, D., and Guthrie E. P. (1997). Discovery and Uses of Novel Glycosidases. Techniques in Glycobiology pages 401-407.
  • Wright, D.J., Jack, W.E. and Modrich P. (1999). The kinetic mechanism of EcoRI endonuclease. J. Biol. Chem. 274:31896-31902.PubMed ID:10542216
  • Wu, H., Xu, M-Q and Liu, X-Q (1998). Protein trans-splicing and functional mini-inteins of a cyanobacterial dnaB intein. Biochim. et Biophys. Acta 35732:1-11.PubMed ID:9748659
  • Xia, Y., Morgan, R., Schildkraut, I., and Van Etten, J. L. (1988). A site-specific single strand endonuclease activity induced by NYs-1 virus infection of a Chlorella-like green alga. Nucl. Acids Res. 16:9477-9487.PubMed ID:3186439
  • Xu, S. Y., and Schildkraut, I. (1991). Isolation of BamHI variants with reduced cleavage activities. J. Biol. Chem. 266:4425-4429.PubMed ID:1999426
  • Xu, S. Y., and Schildkraut, I. (1991). Cofactor requirements of BamHI mutant endonuclease E77K and its suppressor mutants. J. Bacteriol. 173:5030-5035.PubMed ID:1907265
  • Xu, M. Q., Southworth, M. W., Mersha, F. B., Hornstra, L. J., and Perler, F. B. (1993). In vitro protein splicing of purified precursor and the identification of a branched intermediate. Cell 75:1371-1377.PubMed ID:8269515
  • Xu, S., and Schildkraut, I. (1993). Protecting Recognition Sequences on DNA by a Cleavage-Deficient Restriction Endonuclease. BioTechniques 15:310-315.PubMed ID:8396948
  • Xu, S. Y., and Fomenkov, A. (1994). Construction of pSC101 derivatives with Camr and Tetr for selection or LacZ' for blue/white screening. Biotechniques 17:57.PubMed ID:7946313
  • Xu, M. Q., Comb, D. G., Paulus, H., Noren, C. J., Shao, Y., and Perler, F. B. (1994). Protein splicing: an analysis of the branched intermediate and its resolution by succinimide formation. EMBO J. 13:5517-5522.PubMed ID:7988548
  • Xu, M. Q., and Perler, F. B. (1996). The mechanism of protein splicing and its modulation by mutation. EMBO J. 15:5146-5153.PubMed ID:8895558
  • Xu, S. Y., Xiao, J. P., Posfai, J., Maunus, R., and Benner, J. (1997). Cloning of the BssHII restriction-modification system in Escherichia coli: BssHII methyltransferase contains circularly permuted cytosine-5 methyltransferase motifs. Nucl. Acids Res. 25:3991-3994.PubMed ID:9321648
  • Xu, S. Y., Xiao, Ettwiller L., holden, M., Aliotta, J., Poh, C. L., Dalton, M., Robinson, D. P., Petronzio, T. R., Moran, L., Ganatra, M., Ware, J., Slatko, B. and Benner, J. (Nov. 1998). Cloning and expression of the ApaLI, NspI, NspHI, SacI, ScaI and SapI restriction-modification systems in Escherichia coli. Mol. Gen. Genet. 260:226-231.PubMed ID:9862476
  • Xu, M. Q., Buckley, D., Guan, C. and Guo, H-C (1999). Structural Insights into the Mechanism of Intramolecular Proteolysis. Cell 98:651-661.PubMed ID:10490104
  • Xu, Q., Stickel, S., Roberts, R.J., Blaser, M.J. and Morgan, R.D. (2000). Purification of the Novel Endonuclease, Hpy188I, and Cloning of Its Restriction-Modification Genes Reveal Evidence of Its Horizontal Transfer to the Helicobacter pylori Genome. J. Biol. Chem. 275(22):17086-17093.PubMed ID:10748211
  • Xu, Q., Morgan, R.D., Roberts, R.J. and Blaser, M.J. (2000A). Identification of type II restriction and modification systems in Helicobacter pylori reveals their substantial diversity among strains. Proc. Natl. Acad. Sci. USA 97:9671-9676.PubMed ID:10944229
  • Xu, M. Q., Paulus, H. and Chong, S. (2000). Fusions to Self-Splicing Inteins for Protein Purification. Methods in Enzymology 326:376-418.PubMed ID:11036654
  • Xu, M. Q. and T.C. Evans, Jr. (2001). Intein-Mediated Ligation and Cyclization of Expressed Proteins. Methods 24:257-277.PubMed ID:11403575
  • Xu, M. Q., Chong, S. and T.C. Evans, Jr. (2001). Protein splicing. Encyclopedia of Genetics.
  • Xu, M.Q., Ghosh, I., Kochinyan, S. and Sun, L. Intein-mediated Peptide Arrays for Epitope Mapping and Kinase-Phosphatase Assays. Methods in Molecular Biology, vol., Microarrays: Methods and Protocols Edited by J.B. Rampal. Humana Press Inc., Totowa, NY. In press.
  • Xu, Y., Lunnen, K. and Kong, H. (2001). Engineering a Nicking Endonuclease N.AlwI by Domain Swapping. Proc. Natl. Acad. Sci. USA 98:12990-12995.PubMed ID:11687651
  • Xu, Q., Morgan, R.D., Roberts, R.J., Xu, S.Y., van Doorn, L.J., Donahue, J.P., Miller, G.G. and Blaser, M.J. (2002). Functional analysis of iceA1, a CATG-recognizing restriction endonuclease gene in Helicobacter pylori. Nucl. Acids Res. 30(17):3839-3847.PubMed ID:12202769
  • Xu, M.-Q. and Evans, T.C., Jr. (2003). Purification of recombinant proteins from E. coli by engineered inteins. Methods Mol. Biol. 205:43-68.PubMed ID:12491879
  • Yuan, J.M., Li, Z.Y., Wang, Y.M. and Xu., M.-Q. (2000). One step purification of recombinant human Neurotrophic factor-3 with the splicing function of intein. Chin. J. Biochem. Mol. Biol. 16:335-339
  • Zardo, G., Reale, A., Passananti, C., Pradhan, S., Bountempo, S., DeMatteis, G., Adams, R.L.P. and Caiafa, P. (2002). Inhibition of poly(ADP-ribosyl)ation induces DNA hypermethylation: a possible molecular mechanism. FASEB J. 16(10):1319-1321.PubMed ID:12154007
  • Zehr, J. P., and McReynolds, L. A. (1989). Use of Degenerate Oligonucleotides for Amplification of the nifH Gene from the Marine Cyanobacterium Trichodesmium thiebautii. Appl. Environ. Microbiol., 55:2522-2526.PubMed ID:2513774
  • Zhang, A., Gonzales, S.M., Cantor, E.J. and Chong, S. (2001). Construction of a mini-intein fusion system to allow both direct monitoring of soluble protein expression and rapid purification of target proteins. Gene 275:241-252. PubMed ID:11587851
  • Zhang, B., Tao, T., Wilson, G. G., and Blumenthal, R. M. (1993). The M.AluI DNA-(cytosine C5)-methyltransferse has an unusually large, partially dispensable, variable region. Nucl. Acids Res. 21:905-911. PubMed ID:8451189
  • Zheng, Y., Szustakowski, J.D., Fortnow, L., Roberts, R.J. and Kasif, S. (2002). Computational Identification of Operons in Microbial Genomes. Genome Research 12:1221-1230.PubMed ID:12176930
  • Zheng, Y., Roberts, R.J. and Kasif, S. (2002A). Genomic functional annotation using co-evolution profiles of gene clusters. Genome Biology 3(11):RESEARCH0060.PubMed ID:12429059
  • Zhou, D.-M., Yi, X.-Y., Zeng, X.-F., Wang, M., Cai, C., Wang, Q.-L., Zhang, S.-K., McReynolds, L. (2002). Cloning, Expression and Immunization of the new antigen gene Sj-Ts4 of Schistosoma japonicum. Acta Biochimica et Biophysica Sinica 34(2):143-148.
  • Zhu, Z., Zhou, J., Friedman, A.M. and Xu, S.-Y. (2003). Isolation of BsoBI restriction endonuclease variants with altered substrate specificity. J. Mol. Biol. 330(2):359-372. PubMed ID:12823974
  • Zwick, M.B., Bonnycastle, L.L.C., Noren, K.A., Venturini, S., Leong, E., Barbas, C.F., Noren, C.J. and Scott, J.K. (1998). The Maltoxe-Binding Protein as a Scaffold for Monovalent Display of Peptides Derived from Phage Libraries. Anal. Biochem. 264:87-97. PubMed ID:9784192