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Home > Products > Protein Tools > Protein Kinases/Substrates/Inhibitors > CK2 Peptide Substrate CK2 Peptide Substrate Catalog # Size Concentration Price Qty   P6012L 2.5 mg 10 mg/ml $220.00 P6012S 0.5 mg 10 mg/ml $55.00 Prices are in US dollars and valid only for US orders. Download: MSDS PDF Description: This synthetic peptide is designed based on the preference of Casein Kinase II (CK2) for serine as the phosphoacceptor residue surrounded by acidic residues. It displays a high selectivity for CK2, being totally unaffected by CK1. The basic arginine residues required for the phosphocellulose assay are located on the N-terminal side at positions where they are not detrimental for the specificity. CK2 phosphorylates this peptide with Km of 15 µM (1-3).  Amino Acid Sequence:  RRRADDSDDDDD (Arg-Arg-Arg-Ala-Asp-Asp-Ser-Asp-Asp-Asp-Asp-Asp)  Purity: CK2 Peptide Substrate is > 95% pure as determined by HPLC and mass spectrometry.  Suggested Working Concentration: Dilution of the supplied solution (10 mg/ml = 6.9 mM) to a final concentration of 100 µM is recommended. Enzyme Properties Protein Kinase Substrate Recognition Molecular Weight: Theoretical: 1,450 daltons Reaction & Storage Conditions Concentration: 10 mg/ml Storage Conditions: 1 X Sterile purified water Storage Temperature: -20°C References Marin, O. et al. (1994) Biochem. Biophys. Res. Commun., 198, 898-905. Yang, Y. and Roach, P. J. (1993) In D. G. Hardie (Ed.). rotein Phosphorylation: A Practical Approach, 122-129. New York: IRL Press. Sarno, S. et al. (1996) J. Biol. Chem., 271, 10595-10601.